This paper discussed the differences in teaching arrangement,material construction,teaching pattern, and teaching methods been used in medical microbiology teaching between China and the United State.

Abdomen ; physiopathology ; Child ; Child, Preschool ; Compartment Syndromes ; diagnosis ; mortality ; therapy ; Female ; Humans ; Infant ; Male ; Retrospective Studies

Objective: To investigate the clinical effects of early enteral nutrition in severe brain injury patients requiring mechanical ventilation. Methods: 56 patients requiring mechanical ventilation were randomly divided into two groups:A(n=28),EEN group peptisorb,1 000 ml a day;B(n=28),control group,PN.The changes of serum total protein,blood albumin,immune globulin,lymphocyte count,nitrogen balance,oxgenation index(PaO2/FiO2),ventilation parameter and blood routine were measured.APACHE Ⅱ,incidence of ventilator-associated pneumoniasurvival rate for 28 days and days in hospital were observed.Results: Incidence of ventilator-associated pneumonia,28 d-survival rate and mean hospitalization day were significantly different(P

Adult ; Child, Preschool ; Heart Ventricles ; pathology ; Humans ; Male ; Myocardium ; pathology ; Pre-Excitation Syndromes ; etiology ; pathology

Objective To investigate the diagnostic value of serum liver function indexes for gallbladder stones combined with asymptomatic secondary common bile duct stones.Methods The retrospective cohort study was conducted.The clinical data of 460 patients with gallbladder stones who were admitted to the Affiliated Hospital of Zunyi Medical College from June 2012 to June 2016 were collected.Of 460 patients,106 combined with asymptomatic secondary common bile duct stones and 354 with gallbladder stones were allocated into the common bile duct stone group and gallbladder stone group,respectively.The serum liver function test was applied to the 2 groups,including alanine transaminase (ALT),aspartate transaminase (AST),total bilirubin (TBil),direct bilirubin (DBil),glutamyltransferase (GGT) and alkaline phosphatase (ALP).The receiver operating characteristic (ROC) curve was built using significant statistical indicators,and correspondent cut-off value,sensitivity and specificity were calculated according to ROC curve.Observation indicators:(1) comparison of serum liver function indicators (ALT,AST,TBil,DBil,GGT,ALP) between the 2 groups;(2) analysis result of ROC curve.Measurement data with normal distribution was represented as x±s.The comparison between groups was evaluated with the independent-sample t test.The comparison of count data were analyzed using the chi-square test.The ROC curve analysis was done for significant statistical indicators.Results (1) Comparison of serum liver function indicators between the 2 groups,the levels of ALT,AST,TBil and DBil were (32±8)U/L,(35±8)U/L,(12.8±2.5)μmol/L,(2.6±0.4)μmol/L in the common bile duct stone group and (30±7)U/L,(32±7)U/L,(12.2± 2.4)μmol/L,(2.5 ±0.4)μmol/L in the gallbladder stone group,respectively,with no statistically significant difference (t=0.891,0.786,0.924,1.026,P＞0.05).The levels of GGT and ALP were (162±43) U/L and (145±37) U/L in the common bile duct stone group and (36± 10)U/L and (128±23) U/L in the gallbladder stone group,respectively,with significantly statistical differences (t =20.859,2.483,P＜0.05).(2) Result of ROC curve showed that areas under the curve of GGT and ALP were respectively 0.963 [95％ confidence interval (CI):0.938-0.988] and 0.621 (95％CI:0.561-0.684).The correspondent cut-off value of diagnostic accuracy,sensitivity and specificity of GGT and ALP were 92.5 U/L and 139.5 U/L,91.6％ and 50.7％,95.7％ and 76.5％,respectively.Conclusion The abnormally elevated levels of serum GGT have major diagnostic value for patients with gallbladder stones combined with asymptomatic secondary common bile duct stones,with an advantage of convenient and fast operation,and it is worth to be applied and popularized.

Acute Disease ; Adolescent ; Female ; Heart Neoplasms ; complications ; Humans ; Hypertrophy, Left Ventricular ; etiology ; Myocardial Infarction ; etiology ; Myxoma ; complications

Capillary Electrochromatography ; Chromatography, Gas ; methods ; Hexanones ; urine ; Humans ; Occupational Exposure

Objective To explore the differences of occupation burnout of the soldiers in southern and northern Xinjiang and explore its related influencing factors.Methods Using stratified randomization sampling method,500 soldiers from south and north of xinjiang military were selected and investigated by Military Job Burnout Scale and Military Social Support Rating Scale.Results ① The military of northern soldiers'accomplishment,somatization,interpersonal relationship,social support score (5.57±3.29,5.53± 3.35,3.38±2.75,9.62± 10.15) was significantly higher than the soldiers who live in south of xinjiang (5.26±3.25,5.13±3.45,2.94±2.39,6.25±5.24) (t=2.091,-2.539,-4.011,7.227,P＜0.05).②Every dimensions of occupation bumout has significant correlation with social support,age,length of military service,marriage,level,working hours,income and job satisfaction (r=0.124,0.220,0.275,0.198,0.192,0.206,0.188,-0.383,P＜0.05).The total score of Military Job Bumout Scale has positive correlation with social support and level (r=0.122、0.410,P＜0.01).③Social support,working hours,job satisfaction and length of military service has forecast effect on the northern military occupation bumout.Social support and level can predict the southern military occupation burnout.Conclusion It is no obviously differences on the general occupational between the north and South Xinjiang Military.Social support is closely related to the job burnout of South and the North military.

Objective To investigate the relationship between gastrin expression and the development of coloreetal neoplasm and cell proliferation.Methods 15 samples of normal coloreetal mucosal tissue,21 samples of coloreetal adenomas and 70 samples of colorectal cancer were selected for evaluation of the expression of gastrin and Ki67 with immunohistochemieal method.Results In normal colorectal mucosal tissues.colorectal adenomas and coloreetal cancer,the positive rates of gastrin expression were 0.28.6%and 25.7%,respectively-which were signff-ieantly hisher in coloreetal cancer and adenomas groups than in the normal colorectal mucosal tissues(P<0.05).But there was no significance between colorectal cancer and adenomas(P>0.05).The positive expression rate of Ki67 with the obove samples were 40.0%,76.2%and 82.8%-respectively,with statistical results identical with results of gastrin(P<0.05).There was significant correlation between gastrin and Ki67[P<0.05).Conclusion Gastrin and Ki67 are highly expressed in eolorectal neoplasm.Gastrin miight play an important role in the carcinogen-esis and development of colorectal neoplasm,and might promote tumor cell proliferation.

Objective To investigate the expression of gastrin, cyclooxygenase-2(COX-2) and Ki-67 in dif-ferent gastric mucosal lesions and to assess the role of gastrin and COX-2 in the sequence of gastric carcinogenesis and its relationship. Methods 96 samples with different gastric mucosal lesions were obtained by gastroscope. The expression of gastrin,COX-2 and Ki-67 was examined with immunohistochemical staining technique(EnVision). Re-sults Positive rates of gastrin expression in chronic superficial gastritis (CSG), chronic atrophic gastritis (CAG), intestinal metaplasia(IM),dysplasia(Dy) and gastric cancer(GC) were 58.8 % ,30. 0% ,57.9 % ,68.2% and 77.8% ,respectively, and there were significant differences between GC and CAG(P<0.05). Positive rates of COX-2 expression in CSG,CAG,IM,Dy and GC were 41.2 % ,45.0% ,68.4 % ,72.7% and 88.9% respectively, and there were significant differences between GC and CAG(P<0.05). Ki-67 proliferation index (PI) from CSG, CAG, IM, Dy to GC also had an increasing tendency. From CAG to GC,the expression of gastrin and COX-2 was positively correlated with PI (P<0.05). The expression between gastrin and COX-2 was correlated significantly in gastric pre-cancerous lesions (P<0.01). PI was increased significantly in group with co-expression of gastrin and COX-2. Con-clusion Gastrin expression is decreased in CAG. From CAG to GC, gastrin expression is increased gradually. COX-2 expression has an increasing tendency in the sequence of gastric cancerization. From CSG to GC, PI is gradually in-creased. Gastrin and COX-2 co-promote proliferation of gastric epithelial cells,and gastrin may take part in up-regu-lation of COX-2 expression in gastric precancerous.