1.Asthma Control in Hospital Tengku Ampuan Afzan, Kuantan, Malaysia: A Cross-sectional Study
The International Medical Journal Malaysia 2015;14(2):41-44
Various initiatives and medications have been introduced to achieve better control of bronchial
asthma. However total control according to Global Initiative for Asthma (GINA) remains elusive even at tertiary
referral hospitals. Our study is to determine the level of asthma control (according to GINA 2009), Asthma
Control Test (ACT) scores and the types of medications used among patients with bronchial asthma in a large
tertiary hospital. Methods: A cross-sectional study of all patients with bronchial asthma who attended the Chest
Clinic at Hospital Tengku Ampuan Afzan (HTAA) from 2009 to 2011. Patient demographics, self-administered ACT
scores, GINA-defined level of asthma control and medications were documented. Results: 208 patients were
recruited. There were 23.2%, 46.3% and 30.5% of patients with controlled, partly controlled and uncontrolled
asthma respectively. The median ACT scores was 19 [inter quartile range (IQR) 6]. The most frequently used
preventer therapy was inhaled long-acting β-agonist/corticosteroids (LABA/ICS) fixed-dose combination (61.7%),
and 9.6% were not on preventer therapy. 75% of patients with controlled asthma were on LABA/ICS compared
to 58.5% of the partly controlled and uncontrolled groups (p=0.039). Conclusion: The majority of the asthmatic
patients attending the Chest Clinic at HTAA did not have GINA-defined controlled asthma. Patients with higher
ACT scores had better control of asthma. There were more patients with controlled asthma who were on LABA/
ICS combination.
2.Role of rigid bronchoscopy in massive haemoptysis
Ng TH ; How SH ; Kuan YC ; R Ahmad MS ; Fauzi AR
Journal of University of Malaya Medical Centre 2010;13(2):107-110
Massive haemoptysis can occur in lung abscess. Massive haemoptysis itself may be life threatening
due to asphyxiation or respiratory failure secondary to acute large airway obstruction by blood
clots. Prompt removal of the obstructing blood clots save life. We describe a case of lung
abscess causing massive haemoptysis resulting in acute airway obstruction which required rigid
bronchoscopy to remove the huge blood clot. (JUMMEC2010; 13(2): 107-110)
Bronchoscopy
3.Airway Y-stent Insertion in Tracheobronchomalacia: A New Experience
Kuan YC ; How SH ; Ng TH ; Mohd Ashri A ; Mohammed Fauzi AR
The International Medical Journal Malaysia 2012;11(1):51-54
This case report describes a rigid bronchoscopy-assisted placement of a silicone airway Y-stent in a patient
who developed tracheobronchomalacia following repeated dilatations for post-tuberculous airway stenosis.
This is the first report of an airway Y-stent insertion in Malaysia.
4.A mimicry of melioidosis by Klebsiella ozaenae infection
TH Ng ; SH How ; YC Kuan ; Adzura ; AA Aziz ; AR Fauzi
The Malaysian Journal of Pathology 2009;31(2):147-150
Klebsiella ozaenae is a Gram negative bacillus. It has been described as a colonizer of oral and
nasopharyngeal mucosa and is a cause of atrophic rhinitis. Klebsiella ozaenae has seldom been
isolated from serious infections. However, several reports have stated that Klebsiella ozaenae may
cause invasive infections and even mortality. We report a 55-year-old man with Klebsiella ozaenae
infection causing abscesses involving the right eye and left kidney and possibly also in the brain,
lungs and prostate. The isolates were sensitive to ceftazidime, ciprofl oxacin, chloramphenicol,
gentamicin and sulfamethoxazole-trimethoprim but resistant to ampicillin. He responded well to
4 weeks of IV ceftazidime and IV amoxycillin-clavulanic acid. To our knowledge, such a multiorgan
infection has not been reported previously for this organism.