1.The Protective Efficacy of Dietary Supplements on Metabolic Syndrome
Ken YASUKAWA ; Kouichi OGAWA ; Yurika TSUDA ; Hideki MATSUBARA
Japanese Journal of Complementary and Alternative Medicine 2012;9(1):57-63
Objective: To show the preventive effect of dietary supplements on metabolic syndrome.
Methods: Twenty dietary supplements were examined for inhibition of α-glucosidase, absorption of sugar in mice, lipids accumulation and adiponectin production in rat visceral adipocytes.
Results: In twenty dietary supplements, Bombyx mori and mulberry leaves inhibited rat intestinal α-glucosidase more than acarbose, and inhibited absorption of sugar in mice. In visceral adipocytes, Ganoderma lucidum, mate and Japanese yew inhibited accumulation of lipid and Artemisia Capillaris Flowers and Ground-ivy increased production of adiponectin in rat visceral adipocytes.
Conclusion: Mulberry leaves, Bombyx mori, Glechoma hederacea, Artemisia Capillaris Flowers are natural products which offer promise in the prevention of diabetes and metabolic syndrome. Incorporating dietary supplements into a treatment plan with medicines with similar effects requires further study.
2.A Case of Chest Pain as an Initial Symptom of Coronary-Pulmonary Arterial Fistula.
Kazunori Ishikawa ; Shunichi Hoshino ; Hirofumi Midorikawa ; Tomohiro Ogawa ; Kouichi Sato
Japanese Journal of Cardiovascular Surgery 2002;31(3):187-190
A 51-year-old woman suffered from a sudden onset of anterior chest pain and was referred to our hospital on the suspicion of an anginal attack. The exercise ECG showed findings of an anterior lesion and ischemia. Coronary angiography also revealed left anterior descending branch fistula and circumflex branch fistula connecting to the main pulmonary artery trunk. Direct closure was performed for both intra-pulmonary openings under cardiopulmonary bypass. The postoperative course was uneventful and the patient did not show any precordial pain. Coronary angiography showed no coronary organic narrowing, but contrast medium remained in the fistulae although there was no left to right shunt. Ligation of the fistulae had to be performed simultaneously to confirm complete obstruction of the coronary-pulmonary arterial fistulae. The antiplatlet agent is administered to the patient to prevent occurring myocardial infarction caused by thrombus which might be formed in fistulae.
3.Acute Stanford Type B Aortic Dissection after Endoluminal Grafting for the Treatment of Descending Thoracic Aortic Aneurysms
Hirofumi Midorikawa ; Tomohiro Ogawa ; Kouichi Satou ; Masayuki Koyama ; Shunichi Hoshino
Japanese Journal of Cardiovascular Surgery 2004;33(1):26-29
A 65-year-old patient underwent successful transluminally placed endoluminal prosthetic grafts (TPEGs) of a descending thoracic aortic aneurysm (dTAA). Two hours after TPEGs, the patient suddenly complained of chest, back pain and right leg pain. Angiography and computed tomography showed acute type B aortic dissection. Re-TPEGs was immediately performed, and the entry was successfully closed. This case suggests that TPEGs for the treatment of acute aortic dissection may be useful for selected patients.
4.A Case with Short Bowel Syndrome Successfully Treated with Shigyakuto-kagen
Keiko OGAWA ; Takao NAMIKI ; Nobuyasu SEKIYA ; Yuji KASAHARA ; Mitsuru CHINO ; Mistuhito NAKAZAKI ; Kouichi NAGAMINE ; Katsutoshi TERASAWA ; Tetsuo AKIBA
Kampo Medicine 2008;59(4):641-645
We present a patient with short bowel syndrome (SBS), successfully treated with the Kampo medicine, shigyakuto-kagen. The patient was a 74 year old female complaining of severe diarrhea, abdominal distention, and abdominal pain. She was diagnosed as having tuberculous peritonitis when she 23 years of age. A partial resection of the small bowel and colon was performed for ileus, secondary to her tuberculous peritonitis, eventually causing her short bowel syndrome (SBS). Severe abdominal distention and pain had persisted even after the resection surgery. She consulted our clinic at 60 years of age in order to receive Kampo therapy. Bukuryoshigyakuto was prescribed, and her condition markedly improved. Zanthoxylum piperitum was added to bukuryoshigyakuto, and the regimen had the reactivity of daikenchuto. She regained her pre-operation body weight. It is significant that this case was followed for 14 years with therapy based on Kampo diagnosis, without remarkable complications, although patients with SBS often tend to have poor prognosis.
Short Bowel Syndrome
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Medicine, Kampo
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Treated with
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Therapeutic procedure
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Peritonitis
5.Intralesional steroid infusion using a spray tube to prevent stenosis after endoscopic submucosal dissection of esophageal cancer
Atsushi GOTO ; Takeshi OKAMOTO ; Ryo OGAWA ; Kouichi HAMABE ; Shinichi HASHIMOTO ; Jun NISHIKAWA ; Taro TAKAMI
Clinical Endoscopy 2022;55(4):520-524
Background/Aims:
Intralesional steroid injections have been administered as prophylaxis for stenosis after esophageal endoscopic submucosal dissection. However, this method carries a risk of potential complications such as perforation because a fine needle is used to directly puncture the postoperative ulcer. We devised a new method of steroid intralesional infusion using a spray tube and evaluated its efficacy and safety.
Methods:
Intralesional steroid infusion using a spray tube was performed on 27 patients who underwent endoscopic submucosal dissection for superficial esophageal cancer with three-quarters or more of the lumen circumference resected. The presence or absence of stenosis, complications, and the number of endoscopic balloon dilations (EBDs) performed were evaluated after treatment.
Results:
Although stenosis was not observed in 22 of the 27 patients, five patients had stenosis and dysphagia requiring EBD. The stenosis in these five patients was relieved after four EBDs. No complications related to intralesional steroid infusion using the spray tube were observed.
Conclusions
Intralesional steroid infusion using a spray tube is a simple and safe technique that is adequately effective in preventing stenosis Clinical trial number (UMIN000037567).