1.A Proposal on the Curriculum of Behavioral Science
Marie Amitani ; Yoshiki Ishikawa ; Akio Inui ; Shigeru Inoue ; Akihito Shimazu ; Shigeki Suwa ; Akira Tsuda ; Akizumi Tsutsumi ; Koji Tsuboi ; Mutsuhiro Nakao ; Takeo Nakayama ; Masahiro Hashizume ; Kazuhiro Yoshiuchi
Medical Education 2015;46(1):37-40
Introduction: No formal curriculum has been formulated for teaching behavioral science to undergraduate medical students in Japan.
Method: We conducted a survey using the Delphi method to investigate the required competency in behavioral science for graduates in medicine. Then, we developed an outcome-oriented curriculum for teaching behavioral science.
Results: We propose an educational module of behavioral science consisting of 15 sessions of 90-minute lectures, small group discussions, and practice.
Discussion: We recommend including not only lectures but also practices according to problem-based learning as well as team-based learning in the curriculum to achieve the target outcome.
2.Indications for Dental Floss Clip Traction During Gastric Endoscopic Submucosal Dissection by LessExperienced Endoscopists
Hirosato TAMARI ; Shiro OKA ; Takahiro KOTACHI ; Hajime TESHIMA ; Junichi MIZUNO ; Motomitsu FUKUHARA ; Hidenori TANAKA ; Akiyoshi TSUBOI ; Ken YAMASHITA ; Ryo YUGE ; Yuji URABE ; Yasuhiko KITADAI ; Koji ARIHIRO ; Shinji TANAKA
Journal of Gastric Cancer 2023;23(4):512-522
Purpose:
Dental floss clip (DFC) traction-assisted endoscopic submucosal dissection (ESD) is widely performed owing to its simplicity. This study aimed to clarify the appropriate indications for the DFC traction method in early gastric cancer when ESD is performed by less-experienced endoscopists.
Methods:
and Methods: We retrospectively analyzed 1,014 consecutive patients who had undergone gastric ESD performed by less-experienced endoscopists between January 2015 and December 2020. Gastric ESD was performed without DFC in all cases before December 2017 [DFC (−) group, 376 cases], and ESD was performed with DFC in all cases after January 2018 [DFC (+) group, 436 cases]. The procedure time and rates of en bloc resection, complete resection, and adverse events of the groups were compared.
Results:
The procedure time did not differ significantly between the 2 groups. However, when comparing lesions >20 mm, the procedure time in the DFC (+) group was significantly shorter than that in the DFC (−) group (95±46 vs. 75±31, P<0.01). The procedure time for lesions located in the greater curvature of the upper or middle stomach and lesions >20 mm located in the lesser curvature side of the stomach in the DFC (+) group was significantly shorter than that in the DFC (−) group.
Conclusions
The indications for DFC during gastric ESD by less-experienced endoscopists include lesions located in the greater curvature of the upper or middle stomach, and lesions >20 mm located in the lesser curvature of the stomach.
3.Factors Associated with Doses of Mood Stabilizers in Real-world Outpatients with Bipolar Disorder
Norio YASUI-FURUKORI ; Naoto ADACHI ; Yukihisa KUBOTA ; Takaharu AZEKAWA ; Eiichiro GOTO ; Koji EDAGAWA ; Eiichi KATSUMOTO ; Seiji HONGO ; Hitoshi UEDA ; Kazuhira MIKI ; Masaki KATO ; Reiji YOSHIMURA ; Atsuo NAKAGAWA ; Toshiaki KIKUCHI ; Takashi TSUBOI ; Koichiro WATANABE ; Kazutaka SHIMODA
Clinical Psychopharmacology and Neuroscience 2020;18(4):599-606
Objective:
Several evidence-based practice guidelines have been developed to better treat bipolar disorder. However, the articles cited in these guidelines were based on clinical or basic studies with specific conditional settings and were not sufficiently based on real-world clinical practice. In particular, there was little information on the doses of mood stabilizers.
Methods:
The MUlticenter treatment SUrvey on BIpolar disorder in Japanese psychiatric clinics (MUSUBI) is a study conducted to accumulate evidence on the real-world practical treatment of bipolar disorder. The questionnaire included patient characteristics such as comorbidities, mental status, treatment period, Global Assessment of Functioning (GAF) score, and details of pharmacological treatment.
Results:
Most patients received mood stabilizers such as lithium (n = 1,317), valproic acid (n = 808), carbamazepine (n = 136), and lamotrigine (n = 665). The dose of lithium was correlated with age, body weight, number of episodes, depression and GAF. The dose of valproic acid was correlated with body weight, number of episodes, presence of a rapid cycle and GAF. The dose of carbamazepine was correlated with age, mania, and the presence of a rapid cycle. The dose of lamotrigine was correlated with the number of episodes, depression, mania, psychotic features, and the presence of a rapid cycle. Doses of coadministered mood stabilizers were significantly correlated, except for the combination of valproic acid and lamotrigine.
Conclusion
The dose of mood stabilizers was selectively administered based on several factors, such as age, body composition, current mood status and functioning. Further prospective studies are required to confirm these findings.