1.A New Technique for Extracting Ovarian Dermoid Cysts during Laparoscopic Surgery
Takanori YOSHIDA ; Tamami ODAI ; Koji SHIMABUKURO
Journal of the Japanese Association of Rural Medicine 2016;65(4):884-888
Laparoscopic ovarian cystectomy is a relatively uncomplicated process, but extraction of the resected cyst can sometimes be difficult, especially with ovarian dermoid cysts. We report here our method of extraction for ovarian cysts measuring 7-10cm, where we trap the cyst laparoscopically and utilize the 12mm trocar of the umbilical port to extract the cyst externally.
2.Detection of High Risk Type HPV by Means of Clinichiptm in Patients with Cervical Dysplasia
Satoshi IKEDA ; Chigusa NAGATA ; Koji SHIMABUKURO ; Keiko SUZUKI
Journal of the Japanese Association of Rural Medicine 2014;63(1):29-34
It is known that uterine cervical cancer is caused by persistent infection with high-risk type of HPV (human papilloma virus). We have run HPV genotyping tests on patients since November, 2011. In 111 cases so far examined, HPV types 16, 52 and 58 were detected with high frequency, but type 18 was with low frequency. This trend was comparable to nationwide tendency. Type 52, 56 and 58 were detected from the patients of advanced age frequently. There weredifferences in HPV infection rate between cytology-negative cases and positive cases, but there was not the difference in HPV typing by cytology-negative and positive patients. Furthermore, it was made clear that the superinfection of HPV who significantly related to the development of tumor. In the cytology negative patients who were followed up because of dysplasia, there are many who are negative for high risk HPV. Therefore, HPV genotyping examination may help physicians determine the relative priority for treatment.
3.A Case of Multiple Right Subclavian Arterial Aneurysms with Dysphagia.
Yuji Suda ; Yasuo Takeuchi ; Akihiko Gomi ; Hayao Nakatani ; Koji Kohno ; Takashi Shimabukuro ; Naoko Nagano
Japanese Journal of Cardiovascular Surgery 1997;26(4):262-264
A 61-year-old woman who presented with symptoms of dysphagia was hospitalized after right subclavian artery aneurysm was diagnosed. A selective right subclavian arteriogram revealed the presence of two large subclavian arterial aneurysms. The operative procedure consisted of aneurysmectomy through a right supuraclavian incision followed by the reconstruction of the blood vessel by end-to-end anastomosis of the right subclavian artery. The postoperative course was uneventful. Multiple subclavian artery aneurysms are rare among peripheral aneurysms. This case was found by the symptoms of dysphagia caused by compression of the esophagus. The etiology of this case is unclear, but most likely was due to trauma.
4.Clinical Study of Catamenial Pneumothorax
Mayumi KOBAYASHI ; Takuya ONUKI ; Masaharu INAGAKI ; Yasuko NISHIDA ; Kaori TAKAGI ; Yoshihide SAGAWA ; Reiko NAKAMURA ; Tamami ODAI ; Yoko FUJIOKA ; Maiko ICHIKAWA ; Seiichi ENDO ; Masae SAKAMOTO ; Koji SHIMABUKURO
Journal of the Japanese Association of Rural Medicine 2015;64(1):56-60
Catamenial pneumothorax (CP) is defined as a form of thoracic endometriosis syndrome (TES) and the clinical manifestations and management of this disease are not consensual. Successful treatment depends on how closely pulmonary specialists and gynecologists work together. Such being the circumstances, we reviewed our experience with CP in terms of treatment and follow-up. We treated surgically many patients with pneumothorax during the period from 1989 to 2014, of which eight cases had endometriosis on the diaphragm, lung or pleura histologically. The median age at the time of operation was 37 (range, 17 to 41). CP was right-sided in seven of the eight patients (87.5%). Six patients underwent an examination with diagnostic laparoscopy and five had positive findings. The median period of follow-up after surgery was 33.5 months (range, 4 to 129 months). Two patients had no recurrence without hormonal therapy. Six other patients experienced a recurrence of pneumothorax, although two patients received dienogest after surgery. The use of only dienogest or both GnRHa and dienogest prevented recurrence in all patients. CP is a critical condition that requires prompt action, so after surgical treatment, the choice of hormonal therapy with a high rate of patient compliance are needed. No recurrence occurred in young patients who had only surgical treatment, suggesting that there were some associations between age and recurrence. Since we succeeded in preventing recurrence after using GnRHa in all cases, we recommend GnRHa or dienogest following GnRHa for the first choice of hormonal therapy after surgery. However, treatment with only dienogest could achieve successful results with no recurrence, so more case studies need to be done to make the best treatment choice for each case.
5.Our Experience with Hyaluronic Acid-Carboxymethylcellulose Membrane in Cesarean Sections
Koji SHIMABUKURO ; Seiichi ENDO ; Yasuko NISHIDA ; Yoshihide SAGAWA ; Kaori TAKAGI ; Mayumi KOBAYASHI ; Reiko NAKAMURA ; Tamami ODAI ; Kotoi TSURANE ; Fumi KURITA ; Yoko FUJIOKA ; Maiko ICHIKAWA ; Naoyuki MIYASAKA ; Masae SAKAMOTO
Journal of the Japanese Association of Rural Medicine 2015;64(2):125-130
Adhesion formation after abdominal surgery is a commonly recognized entity. Many studies have shown that women giving birth by cesarean section are at the risk of developing complications related to the postoperative formation of adhesions including ileus, bowel obstructions, impaired fertility, and chronic abdominal pain. Among several adhesion barriers, one that has been tested in randomized, controlled trials is the hyaluronic cid-carboxymethylcellulose (HA/CMC) membrane (Seprafilm®: Genzyme, Cambridge, MA, USA). This bioresorbable membrane serves as a mechanical barrier between surgically damaged tissues and resorbs afterwards. At our institution, we have used HA/CMC in cesarean sections. We report our experience with this patient population using placement of HA/CMC. This study enrolled 45 women who had undergone cesarean sections twice or more who had received HA/CMC during the previous cesarean section between January 2013 and November 2014. The incidence of adhesions to the area of abdominal wall incisions and uterine surface, intestinal obstructive symptoms, and adverse events were studied. The incidence of adhesions to midline incisions was 4.4% (n=2). The filmy adhesion by major omentum was detected in these two cases. The incidence of adhesions to uterine surface was 2.2% (n=1). The moderate thickness adhesion was detected at the left side of the vesico-uterine peritoneal incision by pelvic peritoneum which did not affect the operative procedure. No symptoms related to intestinal obstructions such as abdominal pains, nausea and vomiting were observed. No adverse events were observed. These three cases had fever which had nothing to do with HA/CMC applications but was attributable respectively to influenza infection, mastitis, phlebitis associated with a needle procedure. HA/CMC was considered a useful adhesion barrier membrane for use in cesarean sections as an adjunct intended to reduce the incidence of postoperative adhesions between the abdominal wall and the underlying viscera such as omentum, small bowel, and between the uterus and surrounding structures.
6.Laparoscopic Round Ligament Psoas Minor Tendon-Hitching: Newly Developed Uterine Prolapse Operation
Koji SHIMABUKURO ; Tamami ODAI ; Takanori YOSHIDA ; Takafumi TSUKADA ; Yukiko NUSHI ; Yasuko NISHIDA ; Kaori TAKAGI ; Reiko NAKAMURA ; Sanae HATTORI ; Naoyuki MIYASAKA ; Maiko ICHIKAWA ; Seiichi ENDO ; Masae SAKAMOTO
Journal of the Japanese Association of Rural Medicine 2016;64(5):815-818
We have developed a new surgical procedure for uterine prolapse of round ligament suspension to the psoas minor tendon by the use of a laparoscope. Here, we describe the new technique and report the outcome of surgery in three cases. Operative procedure: The fundus of the uterus is lifted back up to its natural position by fixing the round ligament of the uterus to the psoas minor tendon after incising the peritoneum covering psoas. It is important to use the tendon as a stronger reattachment site in addition to the psoas major muscle. The round ligament is tacked to the tendon by a 2-0 nonabsorbable suture on bilateral sides. The second suture may be added if the uterus is not appropriately lifted up by the first suture. The retroperioneum is closed by a continuous 3-0 absorbable suture after fixation. Cases: Two patients with severe uterine prolapse and one patient with a mild condition went through the operation safely and have experienced no recurrence for 10 to 24 months. One severely ill patient complained about post -operative right inguinal pain early and another with the severe condition complained that something felt wrong with the right thigh. We propose the operation of laparoscopic round ligament psoas minor tendon-hitching as a safe and effective surgical treatment for uterine prolapse.
7.A Case of Erythropoietin-secreting Large Uterine Leiomyoma
Yasuko NISHIDA ; Seiichi ENDO ; Kaori TAKAGI ; Yukiko NUSHI ; Reiko NAKAMURA ; Tamami ODAI ; Sanae HATTOR ; Maiko ICHIKAWA ; Masae SAKAMOTO ; Koji SHIMABUKURO ; Chigusa NAGATA
Journal of the Japanese Association of Rural Medicine 2016;65(2):244-249
A 59-year-old woman, para 2, attended our hospital for an abdominal mass and atypical genital bleeding. Magnetic resonance imaging revealed a 30×25cm uterine myoma. A preoperative blood examination showed the following results: hemoglobin, 21g/dl; hematocrit, 71.5%; erythropoietin, 38.5mIU/ml; and estradiol, 29.9pg/ml. Abdominal total hysterectomy and bilateral salpingo-oophorectomy were performed, with an estimated blood loss of 1650ml. The weight of the uterus, including the myoma nodule, was 4740g, and the results of histology confirmed the diagnosis of leiomyoma. By postoperative day 28, her hemoglobin, erythropoietin, and estradiol levels had fallen to levels of 15.1g/dl, 6.0mIU/ml, and 5.8pg/ml, respectively, which are normal for a postmenopausal woman. The findings suggest that the leiomyoma secreted erythropoietin and induced erythrocytosis. Estradiol stimulates erythropoietin secretion and enlargement of the leiomyoma. Some studies have shown that erythropoietin is also a growth factor for leiomyoma. More than half of the erythropoietin-producing leiomyomas are detected after menopause. It was discovered that leiomyoma cells can produce aromatase, which transforms androstenedione into estradiol. Although estradiol secretion from the ovaries decreases in the postmenopausal period, the estradiol and erythropoietin autocrine/paracrine system in leiomyoma might promote its own growth after menopause.
8.Study of Intrauterine Fetal Death after 22 Weeks of Gestation
Tamami ODAI ; Maiko ICHIKAWA ; Naoyuki MIYASAKA ; Kaori TAKAGI ; Yasuko NISHIDA ; Yukiko NUSHI ; Reiko NAKAMUARA ; Sanae HATTORI ; Seiichi ENDO ; Masae SAKAMOTO ; Koji SHIMABUKURO
Journal of the Japanese Association of Rural Medicine 2016;65(2):215-221
We researched intrauterine fetal death (IUFD) after 22 weeks of gestation from 2009 to 2014 in our departments. During this period, there were 6236 childbirths and 35 cases (0.56%) resulted in IUFD. We researched the background and causes of IUFD in these 35 cases. The median age was 34 years and advanced maternal age accounted for 48.6% of cases, while elderly primipara accounted for 20%. There were 5 cases (14.3%) of pregnancy after fertility treatment. The median gestational age when IUFD was recognized was 30 weeks, but the gestational age in 4 cases was unclear because of lack of antenatal check-ups. The main risk factors for IUFD were maternal age over 35 (0.95% to 0.40%) and lack of antenatal check-ups (3.7% to 0.5%). The major causes of IUFD were umbilical cord abnormalities (n=10) and placental abruption (n=8), but IUFD of unknown etiology accounted for about 30% of cases. We should better inform mothers about the importance of antenatal check-ups and manage pregnancies carefully for those who have risk factors for IUFD. Furthermore, we should increase research into the causes of stillbirths.
9.A Case of Deep Venous Thrombosis and Pulmonary Thrombosis during Week 29 of Pregnancy
Sanae HATTORI ; Maiko ICHIKAWA ; Shiori OKIKURA ; Haruka MANAYAMA ; Kaori TAKAGI ; Yasuko NISHIDA ; Yukiko NUSHI ; Reiko NAKAMURA ; Tamami ODAI ; Seiichi ENDO ; Masae SAKAMOTO ; Koji SHIMABUKURO
Journal of the Japanese Association of Rural Medicine 2016;65(4):857-861
A major cause of pulmonary thromboembolism (PTE) is deep venous thrombosis (DVT). We report here a case of DVT in a 31-year-old woman during week 29 of her second pregnancy. At week 29, the patient noticed swelling of the left leg and pain in the groin after sitting. At almost week 30, walking became difficult due to pain and she was referred to hospital. Computed tomography (CT) revealed a thrombus from the left common iliac vein to the femoral vein and multiple thrombi in the right pulmonary artery. Blood testing showed elevated D-dimer (3.4μg/ml). Continuous intravenous unfractionated heparin was administered, and the dose was increased due to decreased activated partial thromboplastin time control. Despite conservative therapy for DVT, the thrombi showed no change since admission. At almost week 37, a temporary inferior vena cava filter (t-IVCF) was placed to prevent pulmonary thromboembolism, and she had an uneventful delivery of a baby by Caesarean section. Warfarin was administered postpartum. The t-IVCF was removed 4 days after delivery, and the patient was discharged 10 days after delivery. Within the field of obstetrics, the need for IVCF insertion should be considered on an individual case basis and should not be viewed as a standard option.
10.Utility of Dynamic CT in the Management of Laparoscopic Port-site Hematoma
Koji SHIMABUKURO ; Haruka MANEYAMA ; Tamami ODAI ; Takanori YOSHIDA ; Takafumi TSUKADA ; Shiori KOURI ; Yukiko NUSHI ; Yasuko NISHIDA ; Rie KITANO ; Maiko ICHIKAWA ; Seiichi ENDO ; Masae SAKAMOTO ; Reiko NAKAMURA
Journal of the Japanese Association of Rural Medicine 2017;65(5):1023-1026
We report a case of subcutaneous port-site hematoma developed on day 6 after laparoscopic left-sided salpingooophorectomy. To start the procedure, three ports were placed in the umbilicus and in each lower quadrant using bladeless trocars. No bleeding was observed at the trocar sites after insertion or withdrawal. The patient was discharged on postoperative day (POD) 3, but returned to the emergency outpatient department with acute left lower abdominal pain on POD 6. Dynamic CT revealed a port-site hematoma with active bleeding from a subcutaneous artery. Hemostasis was achieved easily by opening the trocar wound. Dynamic CT was useful to locate the bleeding vessel and enabled use of a minimally invasive procedure to control bleeding.