A 51 years old farmer was in unconscious state when he was brought into our hospital. Four days before admission he handled “Nissol” and low toxic organophshor “Smithion” about 9 hours at his farm of apples.
Three days before he noted nausea, vomiting, headache, dizzines, sweatiness and light fever. In the midnight convulsion of limbs occured. Two days before symptoms became progressively worse.
Examinations on admission revealed depression of blood pressure (100-70), incipient rise of body temperature, low blood sugar level (45 mg/dl), concussion of eye-ball and Babinski's sign.
Then as an intoxication of Nissol we treated the patient with glucose solution (5 or 50%), acetamide, antibiotics, phenobalbital, cardiac stimulants and atropin. Fourteen hours after admission he recovered consciousness.
Low blood sugar level and depression of blood pressure continued while about 7 days.
He was out of hospital on the 20 th day.

We performed mitral valvuloplasty for 25 months old infant with endocardial fibroelastosis (EFE) and 21 months old infant with endomyocardial fibrosis (EMF). These two patients showing good post operative cause, have been followed up during 10 and 1 years respectively. The EFE and EMF are severe and progressive restrictive cardiomyopathy of unknown etiology. Most of cases with EFE and EMF have an enlarged left ventricle with incompetent atrioventricular valve. The prognosis of these patient is usually poor. We believe that the surgical treatment in early phase may be able to improve heart failure and also to protect the progression of these disease. This case with EMF is the first report of successfull surgical treatment for the patients with severe congestive heart failure whithin one year after birth in Japan.