1.Focal reactive soft tissue Lesion of gingiva: a diagnostic dilemma.
Chikkaiah U ; Jaikrishna HJ ; Hemavathy KB ; Gururaju CR ; Jyothi PA ; Kiran M.
Pacific Journal of Medical Sciences 2014;13(1):67-73
There are different types of focal overgrowths which may occur on the gingiva. These growths of gingiva are common and often result from underlying systemic disease, drug induced, local iatrogenic factors and dental plaque. Many of these enlargements are considered to be reactive rather than neoplastic in nature. These reactive lesions are more common in the oral cavity because of the frequency with which the tissues are injured. Clinically differentiating one from the other as specific entity is sometimes difficult. This case report describes one such reactive growth of the gingiva that is not implicated with any underlying systemic disease or drug induced. Clinical, radiographic, histologic characteristic along with the differential diagnosis, treatment and prognosis are discussed with the importance of the proper communication with the patient as she was more anxious about the possibility of the lesion being a carcinoma.
2.Restorative therapy using autologous bone marrow derived mononuclear cells infusion intra-arterially in patients with cerebral palsy: An open label feasibility study
MV Padma Srivastava ; A Bhasin ; S Mohanty ; S Sharma ; U Kiran ; CS Bal ; S Gaikwad ; MB Singh ; R Bhatia ; M Tripathi ; K Prasad ; S Singh ; V Goyal ; G Shukla ; M Behari
Neurology Asia 2011;16(3):231-239
Cerebral Palsy is a common and devastating neurological disorder, with no medical treatment apart
from physiotherapy regimes to alleviate the functional disability. Regenerative medicine using stem
cells has gained momentum in recent years as a possible strategy to repair the injured brain. Present
study was undertaken in a open label series to evaluate the safety, feasibility and observe for any
benefi cial effects of intra-arterial infusion of autologous bone marrow derived mononuclear cells in
patients with cerebral palsy with moderate disability. Functional improvement was assessed using
the motor power and spasticity scales, dystonia and abnormal movements scale and the activities of
daily living scales by modifi ed Barthel Index and modifi ed Rankin Scores. Serial structural imaging
with MRI and functional imaging with FDG-PET scans were done. Of the 30 patients injected with
an average of 10-30 million cells into each carotid artery, improvements were observed in all clinical
scales, and predominantly in the disability scores. No adverse events were noted on a 12 months
follow up.
3.Minimally Invasive Augmented Fixation for Anatomical Reduction of Grade 2 and Grade 3 Listhesis in Patients with Osteoporosis
Parichay J PERIKAL ; Umesh SRIKANTHA ; Krishna C JOSHI ; Aniruddha T JAGANNATH ; Kiran KHANAPURE ; Ravi Gopal VARMA ; Sathyaranjandas Alanga HEGDE
Asian Spine Journal 2018;12(5):887-892
STUDY DESIGN: A retrospective study. PURPOSE: To study the efficacy of augmented fixation for anatomical reduction of grade 2 and grade 3 listhesis in patients with osteoporosis. OVERVIEW OF LITERATURE: Spondylolisthesis in osteoporotic patients requiring spinal fixation are associated with complications such as loss of surgical construct stability, screw pulling out, and screw loosening. Augmented fixation is a novel strategy to achieve necessary construct integrity. METHODS: Thirteen consecutive patients with grade 2 or grade 3 listhesis, with proven osteoporosis on dual energy X-ray absorptiometry (DEXA) scan, and who underwent augmented fixation for reduction of listhesis were retrospectively analyzed. In all patients, surgical access was achieved with a fixed 22 mm tubular retractor. A modified technique of bilateral, sequential, transforaminal decompression and discectomy, followed by reduction of listhesis using unilaterally placed augmented screws was employed in all the cases. Patients were followed up with plain X-rays at regular intervals to assess for implant stability and fusion status. All patients were started on medical treatment for osteoporosis. RESULTS: The mean age of the patients was 52.46 years, with 12 females and one male. The median T-score on DEXA scan was −3.0. Of the 13 patients, listhesis was at L4–L5 in five and at L5–S1 in eight. Nine patients had grade 2 listhesis, while four patients had grade 3 listhesis. Complete reduction was achieved in 10 patients. The median duration of follow-up was 18 months. Postoperative outcomes were satisfactory in all cases. CONCLUSIONS: Augmented fixation is a useful technique for achieving anatomical reduction of listhesis in patients with osteoporosis.
Absorptiometry, Photon
;
Decompression
;
Diskectomy
;
Female
;
Follow-Up Studies
;
Humans
;
Male
;
Minimally Invasive Surgical Procedures
;
Osteoporosis
;
Retrospective Studies
;
Spinal Fusion
;
Spondylolisthesis
4.Rare finding of Eustachian tube calcifications with cone-beam computed tomography.
Ali Z SYED ; Anna HAWKINS ; Leela Subashini ALLURI ; Buthainah JADALLAH ; Kiran SHAHID ; Michael LANDERS ; Hussein M ASSAF
Imaging Science in Dentistry 2017;47(4):275-279
Soft tissue calcification is a pathological condition in which calcium and phosphate salts are deposited in the soft tissue organic matrix. This study presents an unusual calcification noted in the cartilaginous portion of the Eustachian tube. A 67-year-old woman presented for dental treatment, specifically for implant placement, and cone-beam computed tomography (CBCT) was performed. The CBCT scan was reviewed by a board-certified oral and maxillofacial radiologist and revealed incidental findings of 2 distinct calcifications in the cartilaginous portion of the Eustachian tube. To the authors' knowledge, no previous study has reported the diagnosis of Eustachian tube calcification using CBCT. This report describes an uncommon variant of Eustachian tube calcification, which has a significant didactic value because such cases are seldom illustrated either in textbooks or in the literature. This case once again underscores the importance of having CBCT scans evaluated by a board-certified oral and maxillofacial radiologist.
Aged
;
Calcinosis
;
Calcium
;
Cone-Beam Computed Tomography*
;
Diagnosis
;
Eustachian Tube*
;
Female
;
Humans
;
Incidental Findings
;
Radiography
;
Salts
5.Higher frequency of Yq microdeletions in sperm DNA as compared to DNA isolated from blood.
Rima DADA ; Rakesh KUMAR ; M B SHAMSI ; Rajeev KUMAR ; Kiran KUCHERIA ; Raj K SHARMA ; Satish K GUPTA ; Narmada P GUPTA
Asian Journal of Andrology 2007;9(5):720-722
AIMTo determine if Yq microdeletion frequency and loci of deletion are similar in two tissues (blood and sperm) of different embryological origin.
METHODSThe present study included 52 infertile oligozoospermic cases. In each case, DNA was isolated from blood and sperms and polymerase chain reaction (PCR) microdeletion analysis was done from genomic DNA isolated from both the tissues. The PCR products were analyzed on a 1.8% agarose gel. PCR amplifications found to be negative were repeated at least three times to confirm the deletion of a given marker.
RESULTSOnly 1 case harbored microdeletion in blood DNA, whereas 4 cases harbored microdeletion in sperm DNA.
CONCLUSIONThe frequency of Yq microdeletions is higher in germ cells as compared to blood. As the majority of infertile couples opt for assisted reproduction procreation techniques (ART), Yq microdeletion screening from germ cells is important to understand the genetic basis of infertility, to provide comprehensive counseling and most adapted therapeutics to the infertile couple.
Chromosomes, Human, Y ; genetics ; DNA ; blood ; genetics ; isolation & purification ; Humans ; Male ; Repetitive Sequences, Nucleic Acid ; Sequence Deletion ; Spermatozoa ; physiology
6.A variant deep femoral artery passing anterior to femoral vein: an anatomical observation with implication in femoral vein cannulation
Mohammadali M. SHOJA ; Maria-Teresa DE LEON ; Jay SHETH ; Sana PADIVAL ; Tara TRITSCH ; Gary B. SCHWARTZ
Anatomy & Cell Biology 2024;57(4):616-620
The common femoral artery (CFA) typically gives rise to its superficial and deep branches, with the deep femoral artery (DFA) being the largest and most substantial of these branches. This case study presents a rare variation of the DFA characterized by an unusual branching pattern and its specific relationship with the femoral vein within the subinguinal region. In nutshell, the DFA and the medial femoral circumflex artery shared a common origin from the medial aspect of the CFA. The DFA assumed an unusual course, initially passing anterior to the femoral vein above the saphenofemoral junction, followed by a spiraling trajectory around the medial aspect of the femoral vein before running posteriorly. The embryological origins and clinical implications of this anatomical variation are thoroughly examined. This unusual vascular relationship in the subinguinal region may potentially result in arterial injury during femoral vein cannulation or formation of arteriovenous fistula after the procedure.
7.A variant deep femoral artery passing anterior to femoral vein: an anatomical observation with implication in femoral vein cannulation
Mohammadali M. SHOJA ; Maria-Teresa DE LEON ; Jay SHETH ; Sana PADIVAL ; Tara TRITSCH ; Gary B. SCHWARTZ
Anatomy & Cell Biology 2024;57(4):616-620
The common femoral artery (CFA) typically gives rise to its superficial and deep branches, with the deep femoral artery (DFA) being the largest and most substantial of these branches. This case study presents a rare variation of the DFA characterized by an unusual branching pattern and its specific relationship with the femoral vein within the subinguinal region. In nutshell, the DFA and the medial femoral circumflex artery shared a common origin from the medial aspect of the CFA. The DFA assumed an unusual course, initially passing anterior to the femoral vein above the saphenofemoral junction, followed by a spiraling trajectory around the medial aspect of the femoral vein before running posteriorly. The embryological origins and clinical implications of this anatomical variation are thoroughly examined. This unusual vascular relationship in the subinguinal region may potentially result in arterial injury during femoral vein cannulation or formation of arteriovenous fistula after the procedure.
8.A variant deep femoral artery passing anterior to femoral vein: an anatomical observation with implication in femoral vein cannulation
Mohammadali M. SHOJA ; Maria-Teresa DE LEON ; Jay SHETH ; Sana PADIVAL ; Tara TRITSCH ; Gary B. SCHWARTZ
Anatomy & Cell Biology 2024;57(4):616-620
The common femoral artery (CFA) typically gives rise to its superficial and deep branches, with the deep femoral artery (DFA) being the largest and most substantial of these branches. This case study presents a rare variation of the DFA characterized by an unusual branching pattern and its specific relationship with the femoral vein within the subinguinal region. In nutshell, the DFA and the medial femoral circumflex artery shared a common origin from the medial aspect of the CFA. The DFA assumed an unusual course, initially passing anterior to the femoral vein above the saphenofemoral junction, followed by a spiraling trajectory around the medial aspect of the femoral vein before running posteriorly. The embryological origins and clinical implications of this anatomical variation are thoroughly examined. This unusual vascular relationship in the subinguinal region may potentially result in arterial injury during femoral vein cannulation or formation of arteriovenous fistula after the procedure.
9.A variant deep femoral artery passing anterior to femoral vein: an anatomical observation with implication in femoral vein cannulation
Mohammadali M. SHOJA ; Maria-Teresa DE LEON ; Jay SHETH ; Sana PADIVAL ; Tara TRITSCH ; Gary B. SCHWARTZ
Anatomy & Cell Biology 2024;57(4):616-620
The common femoral artery (CFA) typically gives rise to its superficial and deep branches, with the deep femoral artery (DFA) being the largest and most substantial of these branches. This case study presents a rare variation of the DFA characterized by an unusual branching pattern and its specific relationship with the femoral vein within the subinguinal region. In nutshell, the DFA and the medial femoral circumflex artery shared a common origin from the medial aspect of the CFA. The DFA assumed an unusual course, initially passing anterior to the femoral vein above the saphenofemoral junction, followed by a spiraling trajectory around the medial aspect of the femoral vein before running posteriorly. The embryological origins and clinical implications of this anatomical variation are thoroughly examined. This unusual vascular relationship in the subinguinal region may potentially result in arterial injury during femoral vein cannulation or formation of arteriovenous fistula after the procedure.
10.A variant deep femoral artery passing anterior to femoral vein: an anatomical observation with implication in femoral vein cannulation
Mohammadali M. SHOJA ; Maria-Teresa DE LEON ; Jay SHETH ; Sana PADIVAL ; Tara TRITSCH ; Gary B. SCHWARTZ
Anatomy & Cell Biology 2024;57(4):616-620
The common femoral artery (CFA) typically gives rise to its superficial and deep branches, with the deep femoral artery (DFA) being the largest and most substantial of these branches. This case study presents a rare variation of the DFA characterized by an unusual branching pattern and its specific relationship with the femoral vein within the subinguinal region. In nutshell, the DFA and the medial femoral circumflex artery shared a common origin from the medial aspect of the CFA. The DFA assumed an unusual course, initially passing anterior to the femoral vein above the saphenofemoral junction, followed by a spiraling trajectory around the medial aspect of the femoral vein before running posteriorly. The embryological origins and clinical implications of this anatomical variation are thoroughly examined. This unusual vascular relationship in the subinguinal region may potentially result in arterial injury during femoral vein cannulation or formation of arteriovenous fistula after the procedure.