1.The risk factors of lower limb cellulitis: A casecontrol study in a tertiary centre
Norazirah Md Nor ; Khor Inn Shih ; Adawiyah Jami ; Azmi Mohd Tamil ; Azmawati Mohd Nawi
Malaysian Family Physician 2020;15(1):23-29
Introduction: Lower limb cellulitis is a common superficial skin infection that leads to morbidity
and mortality. Cellulitis risk factors have been well studied in many countries, but to date, not in
Malaysia. Geographical and climate variables may affect risk factors. Early identification of the
preventable risk factors is vital to prevent cellulitis and improve holistic patient care.
Objective: To determine the risk factors of lower limb cellulitis amongst hospitalized patients at
a tertiary center.
Methods: A prospective case-control study of hospitalized patients with a clinical diagnosis
of lower limb cellulitis was conducted at UKM Medical Centre, January–August 2015. Each
patient was compared to two age and gender-matched control patients. All patients were
interviewed and examined for risk factors of cellulitis.
Results: A total of 96 cellulitis patients and 192 controls participated in this study. The cellulitis
patients included 61 males and 35 females with a mean age of 62.07±15.43 years. The majority
of patients were experiencing their first episode of cellulitis. Multivariate analysis showed a
previous history of cellulitis (OR 25.53; 95% CI 4.73–137.79), sole anomalies (OR 16.32; 95%
CI 6.65–40.06), ulceration (OR 14.86; 95% CI 1.00–219.39), venous insufficiency (OR 10.46
95% CI 1.98–55.22), interdigital intertrigo (OR 8.86; 95% CI 3.33-23.56), eczema (OR 5.74;
95% CI 0.96.–34.21), and limb edema (OR 3.95; 95% CI 1.82–8.59) were the significant risk
factors for lower limb cellulitis.
Conclusion: Previous cellulitis and factors causing skin barrier disruption such as sole anomalies,
ulceration, venous insufficiency, eczema, intertrigo, and limb edema were the risk factors for
lower limb cellulitis. Physician awareness, early detection, and treatment of these factors at the
primary care level may prevent hospital admission and morbidity associated with cellulitis.
2.Misdiagnosis of community-acquired pneumonia in patients admitted to respiratory wards, Penang General Hospital
Ang Choon Seong ; Kelvin Beh Khai Meng ; Yeang Li Jing ; Chin Yuen Quan ; Khor Inn Shih ; Yoon Chee Kin ; Irfhan Ali bin Hyder Al
The Medical Journal of Malaysia 2020;75(4):390-
Introduction: Pneumonia continues to be as one of the top
causes of hospitalisations and deaths in Malaysia despite the
advancement in prevention and treatment of pneumonia. One
of the possible explanations is the frequent misdiagnosis of
pneumonia which had been reported elsewhere but such data is
not available locally.
Objectives: This is an audit project aiming to evaluate the
proportion of misdiagnosis among hospitalised communityacquired pneumonia (CAP) patients in the Respiratory wards
of Penang General Hospital based on their initial presentation
data, and their associated outcomes.
Methods: We reviewed the medical notes and initial chest
radiographs of 188 CAP patients who were admitted to
respiratory wards. Misdiagnosis was defined as cases which
lack suggestive clinical features and/or chest radiograph
changes. In-hospital mortality and length of stay (LOS) were
the outcomes of interest.
Results: The study found that 38.8% (n=73) of the hospitalised
CAP patients were misdiagnosed. The most common
alternative diagnosis was upper respiratory tract infection
(32.8%, n=24). There was no statistical difference between
misdiagnosis and CAP patients in the demographic and clinical
variables collected. In terms of outcomes, misdiagnosed
patients were discharged earlier (mean LOS= 3.5±3.28 days vs.
7.7±15.29 days, p=0.03) but the in-hospital mortality difference
was not statistically significant (p=0.07).
Conclusions: One third of our CAP admissions were
misdiagnosed. Although initial misdiagnosis of CAP in our
study did not show any increase in mortality or morbidity, a
proper diagnosis of CAP will be helpful in preventing
inappropriate prescription of antibiotics and unnecessary
admission.