OBJECTIVE To evaluate the efficacy of radiofrequency ablation on treatment of compensatory turbinate hypertrophy.METHODS A total of 105 patients enrolled in the study.Fifty cases only accepted the relocation of inferior turbinate and 55 cases accepted radiofrequency ablation of inferior turbinate during nasal septum deviation surgery under nasal endoscope.The preoperative and postoperative nasal obstructions were assessed with visual analogue scale(VAS).RESULTS The outcome of 105 patients undergoing different operation for below 1 months,3～6 months,above 6 months after operation were recorded.The results of treatment group were better than that of the control group.CONCLUSION The use of radiofrequency ablation for the treatment of compensatory turbinate hypertrophy is an effective method for reducing symptoms of nasal obstruction after relocation of inferior turbinate.

OBJECTIVE To evaluate the efficacy and the recovery of laryngeal functions of various kinds of partial laryngectomy for glottic carcinoma.METHODS The clinical data of 75 patients with glottic carcinoma who underwent partial laryngectomy in our department from Jan. 1997 to Dec. 2006 were retrospectively analyzed. Seventy one cases were male and 4 cases were female. There were 6 kinds of surgical methods for those patients. CO2 laser assisted vocal cordectomy was operated on in 12 cases,vocal cordectomy through laryngofissure in 18 cases,vertical partial laryngectomy in 33 cases,frontal partial laryngectomy in 5 cases,extended vertical partial laryngectomy in 4 cases,and CHEP in 2 cases. RESULTS The overall 3 and 5 year survival rates of the patients were 97.3% and 94.6% respectively. The 3 and 5 year survival rates in 48 cases with stage T1/T2 were 97.9% and 97.9% and those in 27 cases with stage T3/T4 were 92.5% and 85.1%. All of the patients restored the phonation and swallowing function. The decannulation rate was 92.1%(58/63). The decannulation rate of the patients within one month after operation was 85.2% CONCLUSION Partial laryngectomy is the first choice of the radical treatments for glottic carcinoma. Strict indications,correct procedure and surgical repair methods are the keys to ensure the efficacy and preservation of laryngeal function.

0.05).But for the patients with wide-base vocal cord polyps,the effective rate of self-retaining laryngoscope group was higher than that of electronic laryngoscope(P

OBJECTIVE: To study the correlation between the bacterial biofilm formation and bacterial culture in chronic otitis media. METHOD: As a prospective reserch, we used scanning electron microscopy to examinate patients samples which collected from 32 cases of patients with chronic suppurative otitis media and middle ear cholesteatoma in the operations, and performed the middle ear secretions bacterial culture. According to the different types of chronic otitis media group, we analysised the relationship between chronic otitis media bacterial biofilm formation and the bacterial culture results. RESULT: Chronic suppurative otitis media (activity) and middle ear cholesteatoma bacterial biofilm formation rate were 87.5%, 81.3%, chi-square (P > 0.05). Compared bacterial biofilm results with the results of bacterial cultured in chronic otitis media, sensitivity was 70.37%, specificity was 60.00%, the misdiagnosis rate was 40.00%, the missed diagnosis was 29.63%, positive predictive value was 90. 46%, negative predictive value was 27.27%, accuracy was 68.75%. Youden index was 30. 37%, and Pearson correlation coefficient was 0.232 (P > 0.05). CONCLUSION Chronic suppurative otitis media (activity) and middle ear cholesteatoma bacteria had a higher biofilm formation rate. The routine bacterial culture results can't reflecte bacterial biofilm formation in chronic otitis media. We need to explore more reliable experimental methods to accurately reveal the infection status of chronic otitis media.
Adolescent ; Adult ; Bacteria ; growth & development ; Biofilms ; Cholesteatoma, Middle Ear ; microbiology ; Chronic Disease ; Female ; Humans ; Male ; Middle Aged ; Otitis Media, Suppurative ; microbiology ; Sensitivity and Specificity ; Young Adult

OBJECTIVETo investigate the therapeutic effect of drug treatment for patients with sudden sensorineural hearing loss (SSNHL) accompanied with feeling of ear fullness (FEF).

METHODSA prospective clinical multicenter research was carried out from August 2007 to October 2011. SSNHL patients aged between 18 to 65 years old and accepted no medication were recruited, with a duration less than two weeks. The patients were divided into four types according to the hearing curve: type A was acute SSNHL in low tone frequencies, type B was acute SSNHL in high tone frequencies, type C was acute SSNHL in all frequencies, and type D was total deafness. Each type was subdivided into two groups by the accompaniment of SEF or not. And each type had four different treatment programs, based on the unified designed randomized table. All patients were followed up for four weeks from the initial examination.

RESULTSA total of 1 024 cases with single side SSNHL were recruited in the study from 33 hospitals in China, including 565 cases accompanied with FEF (55.18%), and 459 cases without FEF (44.82%). By classification of audiogram, 205 cases were type A (20.20%), of whom 122 were accompanied with FEF (59.51%); 141 cases belonged to type B (13.77%), of whom 74 were accompanied with FEF (52.48%); 402 cases were type C (39.25%), of whom 229 were accompanied with FEF (56.97%); and 276 cases were classified as type D (26.95%), of whom 140 were accompanied with FEF (50.72%). No significant difference was observed in total effective rate between the SSNHL patients accompanied with FEF or not in four acoustic types (P > 0.05). Among four acoustic types, the clinical cure rate of patients accompanied with FEF in type A was 93.44%, ranking the first; followed by 84.28% for type C; 75.71% for type D; and 70.27% for type B, respectively.

CONCLUSIONSThe therapeutic effect for patients accompanied with FEF in type A is satisfactory. The presence of FEF do not impact the therapeutic effect for SSNHL patients.

Adolescent ; Adult ; Aged ; China ; Hearing Loss, Sensorineural ; therapy ; Hearing Loss, Sudden ; therapy ; Hearing Tests ; Humans ; Middle Aged ; Prospective Studies ; Young Adult