1.China's social non-profit medical institutions:Motivations, challenges and countermeasures
Chinese Journal of Health Policy 2016;9(9):1-6
Social forces participating in non-profit medical institutions will help to insist on the commonweal of public medical and health care and realize the goal of access to basic medical and health services for everyone .At present , social forces participating in non-profit medical institutions have made some prominent improvements under a series of policy support .However , due to the absolute dominance of public hospitals , social forces participating in non-profit medical institutions are still potting a lot of restrictions on access threshold of basic medical services , devel-opment space and policy implementation .In order to promote the healthy development of social forces participating in non-profit medical institutions , we should first recognize its significance and guarantee its development potential , tal-ents construction and development space through implementing preferential policies , improving supervision mecha-nisms, exploring multi-sited license, optimizing allocation of resources and so on .
2.Applications of porous inorganic materials in biomedicine and medicine
Haijun WANG ; Keyong ZHANG ; Yaqin LIU
Chinese Journal of Tissue Engineering Research 2008;12(41):8189-8192
Porous inorganic materials are solid-state compounds with regular porous structure.crystal or amorphous,which are closely related to the biochemical processes and wide applied in industry and daily life.Porous inorganic materials are a new kind Of functional materials due to their intriguing molecular topologies and wide distribution range of internal pore size.They have attracted tremendous attention due to comprehensive potential applications in ion exchange.selective adsorption.and catalysiS.This paper reviews researches and prospects of the applications of porous inorganic materials in the field of biology and medicine recently.Applications of porous inorganic materials in the field of biology and medicine mostly include the enzyme immobilizing,enzyme simulation. bioiogical sensors,controlled release drug carrier,antibacterial and auxiliary of anticancer drugs,etc.
3.Comparative study of standard large trauma craniectomy and routine temporoparietal craniectomy in treating acute posttraumatic brain swelling
Wusi QIU ; Qizhou JIANG ; Zhiliang ZHANG ; Keyong CHEN ; Weiguo LIU
Chinese Journal of Postgraduates of Medicine 2006;0(05):-
Objective To investigate the clinical effects of standard large trauma craniectomy in patients with acute posttraumatic brain swelling. Methods A cohort study was performed in 74 patients of acute posttraumatic brain swelling with midline shifting more than 5 mm, who were divided randomly into two groups: standard large trauma craniectomy group (n =37) and routine temporoparietal craniectomy group as control group (n =37). The vital sign, the intracranial pressure (ICP) and complications were observed during the treatment. The Glasgow outcome scale (GOS) and mortality rate as well as the complications were evaluated after treatment. Results The mean ICP in the large trauma craniectomy group at 24, 48, 72 and 96 hours was much lower than those of the control group ( P
4.Effects of Shuanglong Prescription on Heart Hemodynamics and Myocardial Oxygen Consumption in Dogs
Lianda LI ; Yikui LI ; Keyong NING ; Rongli ZHANG ; Jun HE
Traditional Chinese Drug Research & Clinical Pharmacology 2000;0(06):-
Objective To investigate the pharmacological action of Shuanglong Prescription on cardiac function in dogs and to study its mechanism. Methods The changes of the parameters such as coronary blood flow, myocardial oxygen consumption and heart rates were observed in normal anesthetic dogs. Results Compared to those in the normal group, the coronary blood flow increased and the heart rates decreased in Shuanglong Prescription group. Conclusion Shuanglong Prescription can regulate and improve the cardiac function of dogs.
5.Effect of empathy on the insight in patients with first-episode schizophrenia
Ling CHEN ; Keyong WANG ; Xiaoming KONG ; Loufeng ZHANG
Chinese Journal of Behavioral Medicine and Brain Science 2015;24(6):525-527
Objective To investigate the effects of empathy on the insight of first-episode schizophrenia.Methods Empathy with tbe interpersonal reactivity index-C (IRI-C) was applied to 71 patients with first-episode schizophrenia and 69 healthy controls.In addition,schizophrenic patients were evaluated with scale of unawareness of mental disorder (SUMD) for the scores of clinical insight and positive and negative syndrome scale (PANSS) for clinical symptoms.Results Compared with the control group,the schizophrenic patients showed lower scores in the perspective taking ((13.85±1.86) vs (6.74±2.56),P<0.01),empathic concern ((14.28±2.16) vs (17.49± 2.73),P<0.01) of IRI-C,but higher subscale score ((10.28±2.78) vs (8.93±1.93),P<0.01) in personal distress.Pearson correlation analysis showed that,there were negatively significant correlations between insight score and perspective taking (r=-0.429,P<0.01),empathic concern (r=-0.709,P<0.01) subscores of IRI-C respectively.In addition,the insight total score was positively correlated with the positive symptoms subscores (r=0.545,P<0.01) of PANSS.Conclusion Patients with first-episode schizophrenia have significant empathy defects.And the empathic deficits are associated with the insight impairment among the schizophrenic patients,suggesting that patients' insight level can change by improving their empathy ability.
6.Apparent Diffusion Coefifcient and Diffusion Weighted Imaging Findings in Portal Vein Tumor Thrombus Caused by Hepatic Carcinoma
Keyong HUANG ; Huiqing DING ; Changcheng LI ; Mingzhong ZHANG ; Chunyang LI
Chinese Journal of Medical Imaging 2015;23(8):602-605
Purpose To explore the findings and diagnostic values of apparent diffusion coefficient (ADC) and diffusion weighted image (DWI) of the portal venous tumor thrombus (PVTT) caused by hepatic carcinoma.Materials and Methods Thirty-one patients with hepatic carcinoma (43 lesions) with 63 PVTT in the main branches and trunks diagnosed by clinical and MRI were enrolled. All patients underwent conventional MRI (cMRI) imaging, DWI and ADC imaging, the features of cMRI, DWI and ADC were observed, the relevance of ADC values between the hepatic carcinoma lesion and PVTT were analyzed.Results Among the total 43 lesions, DWI image showed low signal, iso-signal and high signal in 1, 4 and 38 lesions, respectively; and ADC image showed low signal, iso-signal and high signal in 36, 5 and 2 lesions, respectively. In the total 63 PVTT, DWI showed low signal, iso-signal and high signal in 4, 7 and 52 lesions, respectively;while their ADC images showed low signal, iso-signal and high signal in 54, 6 and 3 branches, respectively. There was good consistency for the results of two observers on the findings of ADC of tumor lesions (Kappa=0.8334,P<0.05), and a moderate consistency on that of PVTT (Kappa=0.5215,P<0.05). The average ADC value of tumor lesion and PVTT was (1.127±0.268)×10-3 mm2/s and (1.021±0.363)×10-3 mm2/s, respectively; there was a correlation of the mean values of ADC between tumor lesion and PVTT (r=0.246,P<0.05). Conclusion The features such as low signal and low value on ADC image and high signal on DWI obtain a certain clinical application value for qualitative diagnoses of PVTT.
7.Effect of arterial baroreflex on survival rate of rats with cecal ligation and puncture-induced sepsis
Keyong SHI ; Xiujuan MA ; Yinglin CAO ; Wei ZHANG ; Fuming SHEN
Academic Journal of Second Military Medical University 2000;0(07):-
Objective:To investigate the effect of arterial baroreflex(ABR)on survival rate of rats with cecal ligation and puncture(CLP)-induced sepsis.Methods:Male Sprague-Dawley rats were divided into 2 groups:sham-operated rats(n=22)and sinoaortic denervated(SAD)rats(n=22).Four weeks after SAD rats were subjected to CLP-induced sepsis,the blood pressure and heart period(HP)were monitored for 12 hours in conscious state and the survival of rats was observed.Results:Both the diastolic and systolic blood pressue gradually decreased after CLP;the HP shortened first and then drastically prolonged until the death of rats.At 12 h after CLP the survival rate of SAD rats was lower than that of the sham-operated rats(59% vs 86%).Significant differences were found between the Kaplan-Meier survival curves of the rats in 2 groups(P
8.Association of oxygen saturation of arterial hemoglobin with late-onsethypertension in Chinese Han population resided in the Daxinganling area
Xueyan LI ; Hao ZHANG ; Ningning WANG ; Li ZHOU ; Jingping LI ; Keyong ZHANG ; Changchun QIU
Basic & Clinical Medicine 2017;37(8):1077-1081
Objective To identify the association of oxygen saturation of arterial hemoglobin (SaO2) with late-onset hypertension in the Chinese Han population located in the Daxinganling area.Methods A total participants were selected by convenience sampling methods from the Daxinganling area.All data were collected from each person by the questionnaire record of physical examinations as well as biochemical index measuring.SaO2 was noninvasively measured with finger pulse oxymetry,the reported SaO2 was the average of three readings taken 10 seconds apart.Results There were significant differences for SaO2 within the population of individuals,the mean SaO2 values was 97.71%±6.14%,with range from 88% to 100%.There was association of SaO2 with sex,BMI and age.SaO2 level declined with BMI and age increasing.Particularly,it was found that the risk increasing to hypertension was marked association with SaO2 rapid drop.During the period from 40-50 years of age,SaO2 declined from 97.85% to 97.64%,The risk to hypertension increased more than 10 times(P<0.001).That implicated hypoxia mightinvolve in the etiology of hypertension.Conclusions The preliminary results demonstrated the rapid decline of SaO2 with lapse of age may be one of the major risk factors to hypertension,it may be helpful to explain late-onset hypertension to some extent at least.
9.A study of prospective memory in the inpatients with abstinent male alcohol dependence
Qing WU ; Keyong WANG ; Zhihua ZHANG ; Liangjun PANG ; Yongmei WANG ; Bao HUANG ; Wangfa LIU
Chinese Journal of Behavioral Medicine and Brain Science 2013;(2):134-136
Objective To investigate thc cvent-based prospective memory (EBPM)and time-based prospective memory(TBPM)in the inpatients with abstinent alcohol dependence and the relationships between prospective memory and symptoms.Methods 32 male patients with alcohol dependence and 30 normal controls matched by age,education,HAMD and HAMA were assessed with a neuropsychological battery of tests including EBPM and TBPM tasks.Results A statistically significant in EBPM was observed between patients with alcohol dependence and normal controls (3.91 ± 0.69 vs.4.47 ± 0.63,t =-3.348,P < 0.0 1) and the same result in TBPM (3.28 ±0.77 vs.4.20 ±0.66,t=-5.032,P<0.01).The positively correlation was showed between the duration of abstinence and EBPM (r =0.444,P < 0.05),as well as TBPM (r =O.423,P < 0.05) in the patients.Conclusion The results suggest abstinent alcohol dependence patients impairs both EBPM and TBPM.PM shows correlated with duration of abstinence moderately in the patients.
10.Therapeutic Effects of Shuanglong Prescription for Myocardial Infarction in Rats
Lianda LI ; Rongli ZHANG ; Chengyuan LIU ; Limao WU ; keyong NING ; Yikui LI
Traditional Chinese Drug Research & Clinical Pharmacology 1993;0(03):-
Objective To study the therapeutic effects of Shuanglong Prescription (SP) for experimental myocardial infarction in rats. Methods Rat models of myocardial infarction were induced by ligation of coronary artery. Fourteen days after treatment, myocardial infarction area, biochemical parameters and myocardial capillary density were detected to observe the effect of SP.Results After 14- day treatment, SP could reduce the area of myocardial infarction, increase the ratio of 6- keto- PGF1? and TXB2 and the capillary density.Conclusion SP has certain therapeutic effect for myocardial infarction in rats.