No abstract available.
Keratins*

No abstract available.
Immunohistochemistry ; Keratins

Granular parakeratosis is a recently recognized disorder of keratinization that is usually confined to intertriginous areas. The histopathologic features are distinctive and diagnostic. Rarely, histopathologic variants such as follicular granular parakeratosis and granular parakeratosis of eccrine ostia have been described. In this report, we describe a rare case of granular parakeratosis mostly confined to eccrine ostia.
Eccrine Glands ; Keratins ; Neck ; Parakeratosis

Disseminated superficial porokeratosis (DSP) is a keratinization disorder characterized by multiple small lesions with a slightly elevated, sharply defined ridge over the whole body. Inflammatory DSP has common clinical features, which involve a several-year history of asymptomatic DSP and the sudden appearance of intensively pruritic erythematous papules over the entire body. These lesions subside within several months, leaving a brownish atrophic lesion. We report on a 64-year-old man who displayed an atypical clinical feature of inflammatory DSP.
Humans ; Keratins ; Middle Aged ; Porokeratosis

Intraosseous epidermal inclusion cyst is a rare benign, cystic lesion. It is thought to result from traumatic implantation of epidermal elements into bone. Radiologic findings of intraosseous epidermal inclusion cysts are well-defined, lytic lesions. It is difficult to diagnose intraosseous epidermal inclusion cyst without pathologic diagnosis. We experienced a 43-year-old man with a history of trauma followed by painless expansion of his left thumb. Radiographs demonstrated a severe expansile, ill-defined lytic lesion with cortical destruction in the distal phalanx of left thumb, mimicking neoplastic bone lesion or infectious lesion. An intraosseous epidermal inclusion cyst was confirmed by pathologic diagnosis, which was lined by stratified squamous epithelium, containing keratinized cellular debris.
Adult ; Epithelium ; Humans ; Keratins ; Thumb

Darier's disease is a genetic disorder of keratinization with autosomal dominant inheritance. Its appearance is usually in the form of greasy, crusted, keratotic yellow-brown papules and plaques found particularly on seborrheic areas of the body. However, there are some clinical variants showing atypical skin lesions. Here we report an unusual case of Darier's disease, which mainly showed prominent comedonal papules over the face.
Darier Disease ; Keratins ; Skin ; Wills

No abstract available.
Fetus* ; Humans* ; Infant, Newborn* ; Keratins*

Thirty two cases of nevus sebaceus were studied by immunohistochemical staining employing three anticytokeratin antibodies(34bE, 34bB, CAM 5.2) and anti-involucrin antibody in order to clarify the biochemical characteristics of the covering epidermis of nevus sebaceus. An attempt was made to compare the expression pattern of these proteins in the epidermis of nevus sebaceus with that in normal skin and in epidermal nevus. Serial sections in all cases were also stained with PAS in attempt to correlate these protein expression with the amount of glycogen in the epidermis of nevus sebaceus. The following results are obtained. 1. The expression of cytokeratin and involucrin in the epidermis of nevus sebaceus was changed as the age of the lesions increased, but we could not identify a uniform pattern according to the age of lesions. 2. Several CAM 5.2 positive cells were found in the basal layer of the epidermis of nevus sebaceus lesion obtained from patients over 10 years of age. 3. The expression of cytokeratin and involucrin did not show any correlation with glycogen content. These results suggest that the covering epidermis of the lesion of nevus sebaceus may not be nevoid proliferation of epidermal nevus.
Epidermis* ; Glycogen ; Humans ; Keratins* ; Nevus* ; Skin

PURPOSE: The purpose of this study was to compare clinical effect of the Langer & Langer technique , the modified Langer & Langer technique and Bruno technique. MATERIAL AND METHODS: 30 patients who have gingiva recession(Miller class I or class II) were carried root coverage. Langer & Langer technique(14 patients/32 tooth), modified Langer & Langer technique(5 patients/10 tooth) and Bruno technique(11 patients/18 tooth) was carried. At baseline and average 3 months after operation, it was estimated clinical index(Pocket depth, gingiva recession, clinical attachment level, keratinized gingiva, scar tissue, root coverage rate) by Williams style probe. RESULT: Root coverage rate is indicated Langer & Langer technique(85%), Modified Langer & Langer technique(86%) and Bruno technique(90%). CONCLUSION: All three of the procedures were effective in gingival recession and improved clinical parameters.
Cicatrix ; Gingiva ; Gingival Recession ; Humans ; Keratins

Clear cell hidradenoma is a relatively infrequent benign tumor that shows differentiation from or toward the structure of the eccrine sweat gland. We report four cases of clear cell hidradenoma which consists mainly of typical clear cells with small numbers of polyhedral cells. Clinically these tumors represented solitary erythematous firm nodular or cystic mass. In immunohistochemical study of one case, polyhedral cells rather than clear cells reacted positively for carcinoembryonic antigen and cytokeratin. We also review the previous reports of clear cell hidradenoma in Korean dermatologic literature.
Acrospiroma* ; Carcinoembryonic Antigen ; Keratins ; Sweat Glands