1.Intracranial invasive fungal aneurysm due to Aspergillus sinusitis successfully treated by voriconazole plus internal carotid artery ligation therapy in an aged woman
Mami Takemoto ; Yasuyuki Ohta ; Koh Tadokoro ; Ryo Sasaki ; Yoshiaki Takahashi ; Kota Sato ; Toru Yamashita ; Nozomi Hishikawa ; Jingwei Shang ; Masafumi Hiramatsu ; Kenji Sugiu ; Tomohito Hishikawa ; Isao Date ; Koji Abe
Neurology Asia 2019;24(4):363-367
A fungal carotid aneurysm is an infrequently occurring infectious aneurysm that is usually treated by
antifungal therapy plus surgical debridement of the infected vessel. We herein report an extremely
rare case involving a patient with a medical history of bladder cancer treated by Bacillus Calmette–
Guérin (BCG) who developed a fungal aneurysm of the internal carotid artery and thrombosis of
the superior ophthalmic vein caused by maxillary Aspergillus sinusitis. The patient was successfully
treated by antifungal, anticoagulant, and antiplatelet drugs combined with internal carotid artery
ligation therapy. Internal carotid artery fungal aneurysm is associated with a high mortality rate, but
the present case suggests that it can be successfully treated by antifungal therapy combined with a
less invasive endovascular therapy.
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