1.Evaluation of pulmonary ventilation/perfusion imaging in monitoring thrombolytic therapy in pulmonary embolism
Guohui RAO ; Muhua CHENG ; Jieming LI ; Weiming LI ; Kening WU ; Chunyi LI
Clinical Medicine of China 2008;24(9):849-850
Objective To investigate the role of pulmonary ventilatioa/perfusion imaging in evaluating thrombolytic therapy in pulmonary embolism (PE).Methods Pulmonary ventilation/perfusion imagng was performed before and one week and three months after thrombolytic therapy in 43 patients with acute PE.Results Among 421 abnormal pulmonary segments in 43 PE cases,199(47.3%) and 231(54.9%) segments were restored to normal 1 week and 3 months later (P<0.05).Of two groups,more abnormal pulmonary segments were restored to normal in those with less than one week's onset (P<0.01).Conclusion As a non-invasive diagnostic method, pulmonary ventilation/perfusion imaging plays an important role in evaluating the therapeutic effectiveness of thrombolytic therapy in patients with PE.
2.Analysis and Evaluation of the Nuclear Medicine Examination Scores
Guohui RAO ; Jieming LI ; Ping HU ; Dianchao YUE ; Kening WU ; Weiming LI
Chinese Journal of Medical Education Research 2006;0(12):-
In order to evaluate our teaching results and improve the teaching quality,we designed this study to analyze the scores of nuclear medicine examination for the students of 2001 majoring in clinical medicine.There were 345 students participating in the examination.The results showed that the scores was Gassion distribution,the average score was 82.26,and the difficulty and discrimination of the test paper were appropriate.This analysis method as an objective index can be used to evaluate the response of teaching in nuclear medicine as well as improve the quality of test paper.
3.Construction of influencing factors model and policy recommendations for quality of primary traditional Chinese medicine health management services
Wenting WANG ; Jianping REN ; Fengchen ZHOU ; Kening LIU ; Liangfeng WU ; Yan SHI ; Yan LI
Chinese Journal of Health Management 2024;18(2):93-98
Objective:To construct the impact factor model of primary traditional Chinese medicine (TCM) health management service quality, and put forward corresponding policy suggestions.Methods:In this cross-sectional study, the typical sampling and random sampling method were used to select 39 insiders of primary TCM health management service from 15 communities in Zhejiang Province from August to October in 2022. Interviews on service projects, implementation effects and impact factors were conducted, the three-level coding of interview record was carried out using the grounded theory research method, a model of impact factor for health management service quality of basic TCM was constructed, and the corresponding policy recommendations were put forward.Results:Based on the open coding of 39 original interview data, a total of 516 reference points were obtained, and 53 initial concepts related to the topic were formed and summarized into 17 first-level categories. Through the summary of main axis coding, 6 main categories of “policy environment”,“health literacy”,“community orientation”,“capacity building”,“health preference” and “conflict of interest” were extracted. The logical correlation between the six main categories were analyzed with selective coding, an impact factor model was constructed in accordance with the story line of factors affecting service quality. The story line of this model was as follows: first, the policy environment was the external guarantee of community TCM service quality; second, as the demand-side of the services, the health literacy and requirement of residents was the regulatory factor for service quality; in addition, the community played the role of the supply-side of the services, the service ability construction was the key factor, and the community functions and target orientation was the internal driving factor, meanwhile, the internal/external conflicts of interest had a negative constraint on the service quality.Conclusions:The guarantee intensity of external policy environment is limited, the service demand side pays insufficient attention, and the service supply side functions are absent at the present stage. It is necessary to improve the external policy environment, deepen the connection between supply and demand sides in the field of TCM health service, promote the capacity building of TCM service at the grass-roots level, balance the interests of relevant departments of TCM service, in order to improve the quality of TCM health management service at the grass-roots level.
4.Survival status and influencing factors of death risk of HIV-infected patients in Hangzhou, 2004-2023
Junfang CHEN ; Ke XU ; Xingliang ZHANG ; Hong WU ; Kening LIU ; Sichao HUANG
Chinese Journal of Epidemiology 2024;45(10):1396-1402
Objective:To analyze the survival status and death factors of confirmed HIV-infected patients in Hangzhou to provide a basis for the formulation of AIDS prevention and treatment strategies.Methods:A retrospective cohort study was conducted. The data were from the HIV/AIDS Comprehensive Response Information Management System of the Chinese Disease Control and Prevention Information System.Epidemiological characteristics of HIV-infected patients were comparied in Hangzhou City from 2004 to 2023 by using chi-square Test. The survival rate of HIV-infected patients in Hangzhou was calculated by the life table method, the survival curves of different subgroups were described by the Kaplan-Meier method, and the Cox proportional hazard regression model was used to analyze the influencing factors of death risk. The SPSS 26.0 software was used for statistical analysis.Results:Among the 9 457 subjects, the total follow-up time was 58 004.18 person-years, 494 patients died, fatality rate of all-cause cases was 0.85 per 100 person-years.The average survival time was 18.59 (95% CI:18.40-18.78) years. Malignant neoplasms and pneumocystis pneumonia were the first (14.37%,71/494) and second (10.73%, 53/494) causes of death, respectively. Death within 6 months after diagnosis accounted for 42.51% (210/494), and suicide accounted for 4.25% (21/494). Multivariate Cox regression analysis showed that compared with those who received antiviral treatment (ART) within 3 months of diagnosis, those who received ART outside 3 months and those who did not receive ART had a 1.65 (95% CI:1.25-2.19) and 20.68 (95% CI:15.80-27.06) times risk of death, respectively. The HIV-infected patients with high CD4 +T lymphocytes (CD4) counts for the first time had a lower risk of death. The risk of death of patients with baseline CD4 counts of 200-349 cells/μl, 350-499 cells/μl, and ≥500 cells/μl was 0.38 (95% CI:0.29-0.49), 0.26 (95% CI:0.19-0.36), 0.21 (95% CI:0.14-0.31) times higher than that of baseline CD4 counts <200 cells/μl, respectively. Conclusions:The overall survival of the HIV-infected patients was good in Hangzhou from 2004 to 2023. Early detection of HIV infection and timely mobilization to participate in ART was the key to improving the survival rate of patients. At the same time, given the suicide problem of HIV-infected patients, suicide surveillance and depression and anxiety screening of HIV-infected patients should be further strengthened, and targeted psychological intervention policies should be implemented.