2.Anti-N-methyl-D-aspartate receptor (NMDAR) Encephalitis in Malaysia: A Review Article
Su Tein Sim ; Peck Kee Chia ; Keng Hong Chhoa ; Bin Shen Chai
Malaysian Journal of Medicine and Health Sciences 2021;17(No.1):163-169
N-methyl-D-aspartate receptor (NMDAR) antibody encephalitis is recognized as an autoimmune encephalitis, which
is due to autoantibodies against synaptic NMDAR. This disorder affects individuals aged 23 months to 76 years and
has a wide range of presentations. In Malaysia, more than 20 cases have been reported. Timely diagnosis and definitive immunotherapy are vital in optimizing functional recovery and prognosis. However, early diagnosis of the
condition is often missed due to low awareness among clinicians in Malaysia. This article gathered the medical literature from Malaysia and highlights the aetio-pathophysiology, clinical presentation and management of the disease.