1.Reflection and Exploration on Strengthening the Hospital′s Party Construction Work in the “New Normal”
Modern Hospital 2016;16(10):1515-1517
To firm grass-roots Party Construction , the Party members , cadres groups , talent teams construction was set as the focus of hospital Party Committee by The First People′s Hospital of YiChang , China Three Gorges University .All the work was due to the new situation of the reform and development of health care , combined with reality , and the theme of scientific development and medical service was highlighted .At the same time, a sustainable health development and core val-ues with hospital characteristics was achieved by effective approach and methods .The grass-root party organizations was en-hanced during that hospital culture construction .
2.Prognostic significance of neutrophil to lymphocyte ratio in patients with hepatocellular carcinoma
Jinsong YE ; Bangde XIANG ; Nengzhi CHEN ; Kelan ZHANG ; Fenghua ZENG ; Tao LUO ; Chong WU ; Zhigang CHEN ; Xiaolong WU ; Yingjun HE ; Wei TIAN ; Haojie YANG
Chinese Journal of Hepatobiliary Surgery 2017;23(3):158-161
Objective To compare the clinical significance of peripheral blood neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in predicting prognosis of patients with hepatocellular carcinoma (HCC).Methods The clinical data of 661 patients with HCC were retrospectively analyzed.Routine peripheral blood test results were used to calculate the NLR and PLR,and the receiver operating characteristic (ROC) curves were drawn.Using the thresholds of NLR and PLR,the patients were divided into the low NLR group and the high NLR group,and the low PLR group and the high PLR group.Overall survival (OS) and disease free survival (DFS) were evaluated by the Kaplan-Meier method.Independent prognostic predictors were determined by the Cox proportional hazard model.Results The NLR and PLR thresholds were 2.790 and 99,respectively.Analysis of the ROC curves showed higher NLR and PLR were significantly associated with poorer OS and DFS (all P < 0.05).Multivariate analysis showed that NLR was an independent risk factor of OS and DFS (both P < 0.05).The results remained unchanged when the NLR was further analyzed by applying different cut-off values of 2.810 and 3.In subgroup analysis,NLR remained an independent factor of Barcelona Clinical Liver Cancer staging system (BCLC) 0/A/B (P < 0.05 for all measurements).Conclusion An elevated preoperative NLR could be a better prognostic predictor for HCC patients in comparison with PLR,especially for BCLC 0/A/B patients.
3.Prognostic significance of albumin-bilirubin grade in patients with hepatocellular carcinoma after R0 resection
Yingjun HE ; Kelan ZHANG ; Fenghua ZENG ; Jinsong YE ; Xianzhong XU ; Haojie YANG ; Bangde XIANG
Chinese Journal of Hepatobiliary Surgery 2018;24(11):747-750
Objective To investigate the significance of albumin-bilirubin (ALBI) score in predicting prognosis of hepatocellular carcinoma (HCC).Methods The clinical data of 644 HCC patients were retrospectively analyzed from May 2010 to May 2013 in the First People's Hospital of Changde City and the Affiliated Tumor Hospital of Guangxi Medical University.Peripheral blood test results were used to calculate ALBI score,and ALBI score was categorized into the following 3 groups:grade 1,grade 2,grade 3.Overall survival(OS) and disease free survival(DFS) were evaluated by the Kaplan-Meier method.And independent prognostic predictors were determined by the Cox proportional hazard model.Results Multivariate analysis showed that ALBI grade 2 was an independent risk factor for OS(P<0.05).The ALBI grade stratified patients into at least two distinct overall survival cohorts (P<0.05),whereas the CP grade did not.The ALBI grade also classified patients with CP grade A patients into two distinct overall survival cohorts (P<0.05).In the subgroup analysis,the ALBI grade seemed to be an independent factor in terms of Barcelona Clinical Liver Cancer staging system(BCLC) 0-C.Conclusion For patients with HCC who underwent R0 resection,the ALBI grade is a good predictor of OS in HCC patients,and the above conclusions is true in patients with BCLC stage 0-C.