To consider what pharmacists can do to prevent patients from having leftover prescription drugs, we conducted a qualitative study about the various causes behind the unused drugs. We interviewed one male and four female home-care patients who had leftover prescription drugs that pharmacists detected via their home visiting service. The Grounded Theory Approach was used for analysis, and two types were identified as “exogenous factors that cause confusion for the patient” and “patient’s personal thoughts and feelings.” “Exogenous factors that cause confusion” involved eight factors, including unsuitable dosing schedule for lifestyle, complex timing for taking medicine, and inadequate support for enhancing patients’ compliance. These factors were divided into ［problems with prescription］ and ［difficult changes to manage］. In “patient’s personal thoughts and feelings,” 16 concepts were identified and their broader concepts comprised six categories: ［distrust of drugs］, ［taking a positive view about one’s own non-compliance］, ［psychological distance from medical staff］, and others. It was assumed that there would be a perception gap of compliance between patients and medical staff. Moreover, patients affirmed their poor compliance and they did not see the occurrence of leftover drugs as a problem. Additionally, psychological distance from medical staff prevents patients from consultation. Therefore, pharmacists should check patients’ compliance for each drug as well as any medical problems. Knowing patients’ inherent mind revealed by this study, the pharmacist can assist medication alongside patients and contribute to the early prevention of unused drugs.

In junior high school, educators with many different types of specialty jobs are involved in “education on the proper use of pharmaceutical products” and “drug-abuse resistance education”. Examples of these different jobs are physical education teachers, school nurses, school pharmacists. The aim of this study was to elucidate novel ideas and new directions in the future of medicine instructional education by clarifying the aims and thoughts of educators with different jobs on the education of pharmaceutical medicines and drug use. Based on the technique of Personal Attitude Construct (PAC) analysis, junior high school staff members involved in “education on the proper use of pharmaceutical products” and “drug-abuse resistance education” were interviewed regarding their aims and thoughts. Their responses were analyzed qualitatively. Five school pharmacists, five school nurses, and four physical education teachers were interviewed. The responses revealed that school pharmacists engaged in student education from the specialized perspective of pharmacology, school nurses engaged in student education from the perspective of imminent situations, and physical education teachers engaged in student education more from the perspective of student environment. This study suggested that “education on the proper use of pharmaceutical products” and “drug-abuse resistance education” should be a collaborative effort, so there were the different perspectives and aims of educators with different specialty jobs in the instruction of junior high school students on these subjects.

Objectives : A pharmacotherapeutic system for safe and proper use of warfarin was developed through physician-pharmacist cooperative practice ; its effects on patient adherence to therapeutic regimens and the therapeutic benefit of warfarin were assessed.
Methods : Subjects were 12 outpatients or home-care patients receiving warfarin. Patients' level of understanding of warfarin therapy and time in therapeutic range (TTR) were used as indices of adherence and therapeutic benefit, respectively. Before the physician examination, patients were interviewed by pharmacists using point-of-care testing with the CoaguChek ^®XS to check their prothrombin time-international normalized ratio (PT-INR). Pharmacists reported status of warfarin administration, any adverse effects, and medication management status to each patient's physician using the medication record or inter-institute information exchange sheet. Patient adherence was assessed before and after the pre-examination interview and changes in TTR were evaluated.
Results : Levels of understanding of warfarin therapy were significantly higher after pharmacists provided medication counseling (immediately before 4.8±1.9 vs 24 weeks after 6.8±2.4 ; P=0.0079, Wilcoxon signed-rank test). TTR significantly improved at 24 weeks after the interview (pre-interview 20.9±29.8% vs post-interview 60.5±30.5%, respectively ; P=0.0024, Wilcoxon signed-rank test).
Conclusion : The results suggest that patients'adherence to warfarin regimens and the therapeutic benefit of warfarin is improved by pharmacists'obtaining information on PT-INR before patients'medical examinations, as well as by utilizing this information to establish a cooperative pharmacotherapeutic system for good TTR management, as supported by a common protocol across pharmacies and medical institutions.