1.The Serum Lipid Lowering Effect of Rugosa Rose Petal Extract Rich in Polyphenols in Adults with High Serum Triglyceride
Takashi YAMAGISHI ; Keiji TAKANO ; Sumio KONDO
Japanese Journal of Complementary and Alternative Medicine 2015;12(1):29-35
Objective: Hypertriglyceridemia or elevated serum triglyceride (TG) is a leading risk factor for developing atherosclerotic cardiovascular diseases.This clinical study was designed to test the potential of polyphenol-rich extract from Rosa rugosa petals (PE) for improving hypertriglyceridemia and other types of dyslipidemia. Methods: An open-label clinical study was conducted on 19 male and female adult subjects with elevated serum TG (120–399 mg/dL), who were intervened the study diet containing (in a daily dose) 200 mg of PE once daily for sss4 weeks.The serum levels of TG and cholesterols were measured at baseline and week-4.The efficacy was evaluated by comparing the measurements at these two timepoints. Results: A significant decrease (P < 0.05) in serum TG, as well as in serum total cholesterol and non HDL-cholesterol, and a marginally significant decrease (P = 0.070) in serum LDL-cholesterol were observed, while serum HDL-cholesterol was virtually not changed.The study diet was well tolerated without any untoward side effect. Conclusions: The PE-containing diet appears to have benefits in improving hypertriglyceridemia and hypercholesterolemia.
2.A structural equation modeling of exercise and physical competence influence on body composition among Japanese high school students
Keiji Ota ; Keisuke Takano ; Kazutoshi Kudo ; Kyoko Kotani ; Kazuhiko Kawabata
Japanese Journal of Physical Fitness and Sports Medicine 2014;63(1):197-204
Exercise is important for body composition promotion. Although many studies have indicated that physical competence promotes exercise participation, there are relatively few studies examining the relationships among these factors. The purpose of the present study was to model the relationships among body composition, exercise habits and physical competence by using structural equation modeling. The subjects were 223 Japanese male and female high school students. Height, lean bone mass and bone area ratio were measured. Exercise habits and physical competence scale including three subscales (perceived physical competence, feeling of control and peer and teacher acceptance) were assessed by self-administered questionnaires. Data were analyzed using structural equation modeling. The model showed acceptable fit indices (GFI = .905, AGFI = .863 CFI = .954, RMSEA = .069). The path from peer and teacher acceptance to exercise habit was significant (β = 0.51, p < .001). Moreover, the path from exercise habits and from perceived physical competence to body composition was significant (respectively β = 0.53; p < .001, β = 0.47, p < .001). We could model the relationships among body composition, exercise habits and physical competence. These results indicate that not only exercise habits but also physical competence promoting exercise participation influence on body composition promotion.
3.Mongolian Traditional Medicine and Medicinal Plants.
Fumihide TAKANO ; Fumihiko YOSHIZAKI ; Shinji FUSHIYA ; Hideki HAYASAKA ; Keiji OHBA ; Javzan Batkhuu ; Chinbat Sanchir ; Badamjav Boldsaikhan
Kampo Medicine 2003;54(5):963-972
We visited Mongolia in the summer of 1999 and again in the summer of 2000, and investigated the traditional and natural medicines of this country. Mongolian traditional medicine is classified into seven categories, namely, massage, acupuncture, herbal medicine, dietary cures, aromatherapy, phlebotomy and sutra recitation. Herbal medicines, as well as acupuncture and massage, are the principal remedies. These remedies are based on Tibetan traditional medicine, which is derived from Indian traditional medicine. In both rural and urban areas, the Mongolian people use many herbs and herbal prescriptions to prevent and cure acute or chronic diseases. Important herbal plant sources, such as the Ephedra and Glycyrrhiza species, are abundant. Since the abandonment of socialism, traditional medicine has made a rapid comeback and is now a popular and important remedy in Mongolia.
4.Ruptured Thoracoabdominal Aortic Aneurysm in an Elderly Patient with Colostomy on the Left Lower Abdomen.
Hirohisa Goto ; Jun Amano ; Hirofumi Nakano ; Ryo Hasegawa ; Kuniyoshi Watanabe ; Tamaki Takano ; Keiji Nishimaki
Japanese Journal of Cardiovascular Surgery 1999;28(5):327-330
A 76-year-old man was admitted to our hospital because of sudden upper abdominal pain and shock status. The patient had undergone Miles' procedure with a colostomy on the left lower abdomen due to rectal cancer at the age of 70 years. CT scans revealed a thoracoabdominal aortic aneurysm. In view of the clinical findings, ruptured aneurysm requiring emergent operation was diagnosed. A left spiral skin incision was made, keeping away from the colostomy. An extraperitoneal approach was selected. The thoracoabdominal aorta was replaced with an artificial graft under partial extracorporeal circulation with femoral arterial and venous cannulation. The postoperative course was uneventful. No paraplegia occurred in spite of no reconstruction of the intercostal arteries due to severe atherosclerotic changes of the aortic wall. The fact that bleeding due to ruptured aneurysm was localized in the extrapleural and extrapritoneal spaces seemed to be an advantageous factor for the success in this case.
5.Type B Acute Aortic Dissection: The Prognosis and Fate of the Dissected Lumen of Nonsurgical Treated Patients.
Kenji SASAKI ; Shigeo TANAKA ; Masatoshi IKESHITA ; Tadahiko SUGIMOTO ; Tasuku SHOJI ; Teruo TAKANO ; Keiji TANAKA ; Tatsuo KUMASAKI ; Toru OYA
Japanese Journal of Cardiovascular Surgery 1993;22(4):322-327
From March 1981 to March 1990, 61 patients with Stanford type B acute aortic dissection were initially treated by conservative therapy. Among these 61 patients, the dissected lumen became occluded due to thrombosis early after diagnosis in 25 patients (Group T) and remained patent in 36 patients (Group P). Twentythree patients in Group T (92%) and 22 patients in Group P (61%) were discharged without major complications related to acute aortic dissection. However, 2 patients in Group T (8%) and 14 patients in Group P (39%) required additional surgical therapy or died during hospitalization. The mean aortic diameter at the time of admission in Group T was smaller than that of Group P (38±3mm vs 43±7mm, p<0.05). During the observation period, there was a tendency for the diameter of the dissected aorta in Group T to decrease, but to increase in Group P. Long-term survival appeared to be better in Group T than in Group P, but there was no significant difference in the overall survival curve. Large aortic diameter at the time of admission and the presence of a true thoracic aortic aneurysm were major contributing factors influencing the prognosis. A long-term follow-up study showed that the dissected lumen reduced or disappeared in 14 of 23 patients in Group T (61%) but only 2 of 16 patients in Group P (12.5%). We concluded that the patients with small dissected aortas and thrombosed dissected lumens (Group T) can recuperate only with conservative therapy. However, patients with large dissected aortas and patent dissected lumen (Group P) may require surgical therapy even in Stanford type B aortic dissection.