1.Measures taken to Prevent and Exterminate Ascaris Infection in Rural District
Akio Uchida ; Shigeaki Nozue ; Keiichi Ogura ; Fuki Uchida ; Yoshiaki Ito
Journal of the Japanese Association of Rural Medicine 1967;14(3-4):218-223
In the five communities of Urakawa, Sakuma-machi, Shizuoka Prefecture, we have taken measures to Prevent and exterminate ascaris infection, and at the same time studied the causes of infection chiefly from the point of view of environmental conditions. The percentages of ascaris egg-carriers showed a significant difference between 1) farmers and non-farmers; 2) families with and without night-soil; 3) amounts of detergent used for cleaning vegetables; 4) persons with and without experience of anthelmintic treatment.
The group of families that showed extremely high rate of positivity were the farmers not provided with night-soil stores, and the farmers provided with such stores showed about the same rate of positivity as non farmers a fact evidences the appreciatng effect of night-soil stores. On the other hand, the rate of positivity among familis that have no night-soil stores but are in the habit of cleaning vegetables with detergent showed no significant difference as compared with the families provided with night-soil storesa positive evidence of the good effect of detergent.
2.RELATIONSHIP BETWEEN MIDDLE-DISTANCE RUNNING PERFORMANCE AND POWERS ESTIMATED FRONT BLOOD LACTATE CONCENTRATION DURING INTERMITTENT RUNNING
YASUNORI MORIOKA ; SHIZUO ITO ; KEIICHI OHBA ; TAKAKO HARA ; JIN UCHIMARU ; HIROSHI AONO ; TARUYA AMEMIYA
Japanese Journal of Physical Fitness and Sports Medicine 2003;52(3):285-294
This study was conducted to clarify the relationship between power estimated by blood lactate movement during intermittent running test (Maximal Anaerobic Running Test : MART), and velocity of middle distance running (V 800 m, V 1500 m) . The subjects were well-trained male middledistance runners (n=8) .
MART consisted of a variable number of 20 seconds runs on a treadmill with a 100 seconds recovery period between runs. The runs were performed ona a 4° incline. After 40 second recovery, earlobe blood samples were taken and blood lactate concentrations were analyzed. The first run was performed at 250 m/min. Velocity of the treadmill was increased by 25 m/min for each consecutive run until volitional exhaustion.
The power requirement associated with the absolute value of blood lactate (La) and relative value of peak blood lactate (PBLa) was determined from the La or %PBLa vs power curve by linear interpolation from the two consecutive La values which were above and below the desired value.
Results were summarized as follows:
(1) Maximal power (Pmax) for MART was correlated positively with V800m (r=0.880, P<0.01) and V1500m (r=0.948, p<0.001) .
(2) Power estimated at 40% value of PBLa (P40%La) correlated positively with V 1500 m (r=0.903, P<0.01), and at 60% value of PBLa (P60%La) was correlated positively with V800m (r=0.835, P<0.01) and 1500m (r=0.936, p<0.001) .
These results indicate that MART is a valid test for estimating middle distance running performance and P40%La, and P60%La are important indexes with 800-m and 1500-m running.
3.Investigation of Inpatient Rehabilitation Outcomes in different Ischemic Stroke Disease Types : Relationships with Leukoaraiosis in MRI
Joe SENDA ; Keiichi ITO ; Kensuke HAMADA ; Tomomitsu KOTAKE ; Hideo KISHIMOTO ; Gen SOBUE
The Japanese Journal of Rehabilitation Medicine 2010;47(8):559-568
Purpose : The aim of this study is to investigate inpatient rehabilitation outcomes in different ischemic stroke disease types. Subjects and methods : Subjects were 178 patients with ischemic stroke transferred from stroke units or emergency units for inpatient rehabilitation at Kami-iida Rehabilitation Hospital. For all patients, National Institutes of Health Stroke Scale (NIHSS) scores were measured on admission. Functional Independence Measure (FIM) scores were also measured both on admission and discharge, and FIM-gain (FIM-g) and FIM-efficiency (FIM-e) values were calculated. The disease types of ischemic stroke were : lacunar (LI) in 16 patients ; atherothrombosis (AI) in 23 ; branch-atheromatous-disease (BAD) in 59 ; artery to artery embolism (A to A) in 18; cardiogenic embolism (CE) in 34 ; undetermined embolism (unable to differentiate from A to A and cardiogenic embolism) in 22 ; the 6 remaining patients were not categorized. Results : There were no significant differences in the NIHSS scores and FIM scores on admission between disease types except for the NIHSS scores in the LI patients. The FIM-e value in A to A patients was significantly lower than those in other types (p<0.05). Moreover, A to A patients have a tendency of severe leukoaraiosis and their MRAs demonstrated high rates of stenosis (≥50%) or occlusion with intracranial arteries. Conclusion : In A to A embolism, significantly lower FIM-e values were found and FIMs at discharge were affected by leukoaraiosis on the basis of large-vessel arteriosclerosis. Our study revealed that inpatient rehabilitation outcomes differed for each ischemic stroke type and appeared to be influenced by leukoaraiosis.
4.Acquisition of methicillin resistance and progression of multiantibiotic resistance in methicillin-resistant Staphylococcus aureus.
Teruyo ITO ; Keiichi HIRAMATSU
Yonsei Medical Journal 1998;39(6):526-533
Methicillin-resistant Staphylococcus aureus (MRSA) produces specific penicillin-binding protein, PBP2', which shows remarkably low affinities to most beta-lactam antibiotics except those such as penicillin G and ampicillin. The region surrounding mecA has been called additional DNA or mec and is thought to be of extraspecies origin. From the study of mec, we found that mec is a novel mobile genetic element and designated as staphylococcal cassette chromosome mec (SCCmec). There are three types of SCCmec. In the past decades, MRSA has become resistant to many antibiotics, such as carbapenems, new quinolones, and minocycline etc. It seems to be a characteristic of MRSA to acquire multi-resistance by accumulating multiple resistance genes around the mecA gene inside SCCmec.
Drug Resistance, Microbial/physiology*
;
Drug Resistance, Multiple/physiology*
;
Methicillin Resistance/physiology*
;
Staphylococcus aureus/physiology*
5.The International Consultation on Incontinence Questionnaire Short Form as a Substitute for 1-Hour Pad Weight Testing in the Evaluation of Urinary Incontinence in Patients With Pelvic Organ Prolapse Undergoing Surgery
Kenji KURODA ; Koetsu HAMAMOTO ; Kazuki KAWAMURA ; Ayako MASUNAGA ; Hiroaki KOBAYASHI ; Akio HORIGUCHI ; Keiichi ITO
International Neurourology Journal 2024;28(3):215-224
Purpose:
Stress urinary incontinence is a postoperative complication occurring in patients with pelvic organ prolapse (POP). Although the 1-hour pad test measures the degree of urinary incontinence qualitatively and quantitatively, some elderly women undergoing POP surgery do not have the daily activities of living to perform the pad test. Therefore, we examined whether the International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF) could be used as an alternative tool for pad tests.
Methods:
We retrospectively evaluated 132 patients with POP. In our hospital, 57 patients were treated by laparoscopic sacrocolpopexy (LSC), whereas 75 were treated by transvaginal mesh surgery (TVM). We measured the changes in symptoms preand postoperatively using the ICIQ-SF and 1-hour pad weight testing, and investigated the correlation between the total plus component question scores of the ICIQ-SF and 1-hour pad weight.
Results:
The preoperative ICIQ total scores in all patients decreased significantly as the amount of leakage on the 1-hour pad weight decreased. The component question scores also decreased significantly with decreasing levels of 1-hour pad weight. The LSC and TVM groups had decreased ICIQ-SF total and component question scores as pad weight decreased. At 12 months postoperatively, the ICIQ total scores in all patients significantly declined as the amount of leakage on the 1-hour pad weight decreased. In the LSC group, the ICIQ-SF total and component question scores also decreased with decreased pad weight, but the differences were not always significant between ICIQ scores and pad weight. In the TVM group, the ICIQ-SF total and component question scores also significantly decreased as the pad weight decreased.
Conclusions
The ICIQ-SF could be an appropriate substitute for the 1-hour pad weight testing in predicting the severity of urinary incontinence. In the future, we hope to predict the level of urine leakage based on the ICIQ-SF score.
6.The International Consultation on Incontinence Questionnaire Short Form as a Substitute for 1-Hour Pad Weight Testing in the Evaluation of Urinary Incontinence in Patients With Pelvic Organ Prolapse Undergoing Surgery
Kenji KURODA ; Koetsu HAMAMOTO ; Kazuki KAWAMURA ; Ayako MASUNAGA ; Hiroaki KOBAYASHI ; Akio HORIGUCHI ; Keiichi ITO
International Neurourology Journal 2024;28(3):215-224
Purpose:
Stress urinary incontinence is a postoperative complication occurring in patients with pelvic organ prolapse (POP). Although the 1-hour pad test measures the degree of urinary incontinence qualitatively and quantitatively, some elderly women undergoing POP surgery do not have the daily activities of living to perform the pad test. Therefore, we examined whether the International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF) could be used as an alternative tool for pad tests.
Methods:
We retrospectively evaluated 132 patients with POP. In our hospital, 57 patients were treated by laparoscopic sacrocolpopexy (LSC), whereas 75 were treated by transvaginal mesh surgery (TVM). We measured the changes in symptoms preand postoperatively using the ICIQ-SF and 1-hour pad weight testing, and investigated the correlation between the total plus component question scores of the ICIQ-SF and 1-hour pad weight.
Results:
The preoperative ICIQ total scores in all patients decreased significantly as the amount of leakage on the 1-hour pad weight decreased. The component question scores also decreased significantly with decreasing levels of 1-hour pad weight. The LSC and TVM groups had decreased ICIQ-SF total and component question scores as pad weight decreased. At 12 months postoperatively, the ICIQ total scores in all patients significantly declined as the amount of leakage on the 1-hour pad weight decreased. In the LSC group, the ICIQ-SF total and component question scores also decreased with decreased pad weight, but the differences were not always significant between ICIQ scores and pad weight. In the TVM group, the ICIQ-SF total and component question scores also significantly decreased as the pad weight decreased.
Conclusions
The ICIQ-SF could be an appropriate substitute for the 1-hour pad weight testing in predicting the severity of urinary incontinence. In the future, we hope to predict the level of urine leakage based on the ICIQ-SF score.
7.The International Consultation on Incontinence Questionnaire Short Form as a Substitute for 1-Hour Pad Weight Testing in the Evaluation of Urinary Incontinence in Patients With Pelvic Organ Prolapse Undergoing Surgery
Kenji KURODA ; Koetsu HAMAMOTO ; Kazuki KAWAMURA ; Ayako MASUNAGA ; Hiroaki KOBAYASHI ; Akio HORIGUCHI ; Keiichi ITO
International Neurourology Journal 2024;28(3):215-224
Purpose:
Stress urinary incontinence is a postoperative complication occurring in patients with pelvic organ prolapse (POP). Although the 1-hour pad test measures the degree of urinary incontinence qualitatively and quantitatively, some elderly women undergoing POP surgery do not have the daily activities of living to perform the pad test. Therefore, we examined whether the International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF) could be used as an alternative tool for pad tests.
Methods:
We retrospectively evaluated 132 patients with POP. In our hospital, 57 patients were treated by laparoscopic sacrocolpopexy (LSC), whereas 75 were treated by transvaginal mesh surgery (TVM). We measured the changes in symptoms preand postoperatively using the ICIQ-SF and 1-hour pad weight testing, and investigated the correlation between the total plus component question scores of the ICIQ-SF and 1-hour pad weight.
Results:
The preoperative ICIQ total scores in all patients decreased significantly as the amount of leakage on the 1-hour pad weight decreased. The component question scores also decreased significantly with decreasing levels of 1-hour pad weight. The LSC and TVM groups had decreased ICIQ-SF total and component question scores as pad weight decreased. At 12 months postoperatively, the ICIQ total scores in all patients significantly declined as the amount of leakage on the 1-hour pad weight decreased. In the LSC group, the ICIQ-SF total and component question scores also decreased with decreased pad weight, but the differences were not always significant between ICIQ scores and pad weight. In the TVM group, the ICIQ-SF total and component question scores also significantly decreased as the pad weight decreased.
Conclusions
The ICIQ-SF could be an appropriate substitute for the 1-hour pad weight testing in predicting the severity of urinary incontinence. In the future, we hope to predict the level of urine leakage based on the ICIQ-SF score.
8.The International Consultation on Incontinence Questionnaire Short Form as a Substitute for 1-Hour Pad Weight Testing in the Evaluation of Urinary Incontinence in Patients With Pelvic Organ Prolapse Undergoing Surgery
Kenji KURODA ; Koetsu HAMAMOTO ; Kazuki KAWAMURA ; Ayako MASUNAGA ; Hiroaki KOBAYASHI ; Akio HORIGUCHI ; Keiichi ITO
International Neurourology Journal 2024;28(3):215-224
Purpose:
Stress urinary incontinence is a postoperative complication occurring in patients with pelvic organ prolapse (POP). Although the 1-hour pad test measures the degree of urinary incontinence qualitatively and quantitatively, some elderly women undergoing POP surgery do not have the daily activities of living to perform the pad test. Therefore, we examined whether the International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF) could be used as an alternative tool for pad tests.
Methods:
We retrospectively evaluated 132 patients with POP. In our hospital, 57 patients were treated by laparoscopic sacrocolpopexy (LSC), whereas 75 were treated by transvaginal mesh surgery (TVM). We measured the changes in symptoms preand postoperatively using the ICIQ-SF and 1-hour pad weight testing, and investigated the correlation between the total plus component question scores of the ICIQ-SF and 1-hour pad weight.
Results:
The preoperative ICIQ total scores in all patients decreased significantly as the amount of leakage on the 1-hour pad weight decreased. The component question scores also decreased significantly with decreasing levels of 1-hour pad weight. The LSC and TVM groups had decreased ICIQ-SF total and component question scores as pad weight decreased. At 12 months postoperatively, the ICIQ total scores in all patients significantly declined as the amount of leakage on the 1-hour pad weight decreased. In the LSC group, the ICIQ-SF total and component question scores also decreased with decreased pad weight, but the differences were not always significant between ICIQ scores and pad weight. In the TVM group, the ICIQ-SF total and component question scores also significantly decreased as the pad weight decreased.
Conclusions
The ICIQ-SF could be an appropriate substitute for the 1-hour pad weight testing in predicting the severity of urinary incontinence. In the future, we hope to predict the level of urine leakage based on the ICIQ-SF score.
9.Successful Endosonography-Guided Drainage of an Intra-Abdominal Abscess in a 1-Year-Old Infant.
Yukiko ITO ; Hiroyuki ISAYAMA ; Yousuke NAKAI ; Gyoutane UMEFUNE ; Tatsuya SATO ; Saori NAKAHARA ; Junko SUWA ; Keiichi KATO ; Ryo NAKATA
Gut and Liver 2016;10(3):483-485
Endoscopic ultrasound (EUS)-guided intervention has been established as a safe, effective and minimally invasive procedure for various diseases in adults, but there have been limited reports in pediatric patients. Herein, we report our experience with successful EUS-guided drainage of an intra-abdominal abscess in a 1-year-old infant concomitant with disseminated intravascular coagulation. The abscess was punctured via the stomach using a standard, convex-type echoendoscope, and the patient's condition improved after naso-cystic catheter placement. Although the clinical course was complicated by delayed hemorrhage from the puncture site, the bleeding was successfully managed by endoscopic hemostasis using a standard forward-viewing endoscope.
Abdominal Abscess*
;
Abscess
;
Adult
;
Catheters
;
Disseminated Intravascular Coagulation
;
Drainage*
;
Endoscopes
;
Hemorrhage
;
Hemostasis, Endoscopic
;
Humans
;
Infant*
;
Punctures
;
Stomach
;
Ultrasonography
10.Genomic Basis for Methicillin Resistance in Staphylococcus aureus.
Keiichi HIRAMATSU ; Teruyo ITO ; Sae TSUBAKISHITA ; Takashi SASAKI ; Fumihiko TAKEUCHI ; Yuh MORIMOTO ; Yuki KATAYAMA ; Miki MATSUO ; Kyoko KUWAHARA-ARAI ; Tomomi HISHINUMA ; Tadashi BABA
Infection and Chemotherapy 2013;45(2):117-136
Since the discovery of the first strain in 1961 in England, MRSA, the most notorious multidrug-resistant hospital pathogen, has spread all over the world. MRSA repeatedly turned down the challenges by number of chemotherapeutics, the fruits of modern organic chemistry. Now, we are in short of effective therapeutic agents against MRSA prevailing among immuno-compromised patients in the hospital. On top of this, we recently became aware of the rise of diverse clones of MRSA, some of which have increased pathogenic potential compared to the classical hospital-associated MRSA, and the others from veterinary sources. They increased rapidly in the community, and started menacing otherwise healthy individuals by causing unexpected acute infection. This review is intended to provide a whole picture of MRSA based on its genetic makeup as a versatile pathogen and our tenacious colonizer.
Adenosine
;
Chemistry, Organic
;
Chromatography, Micellar Electrokinetic Capillary
;
Clone Cells
;
Colon
;
England
;
Fruit
;
Humans
;
Methicillin
;
Methicillin Resistance
;
Methicillin-Resistant Staphylococcus aureus
;
Sprains and Strains
;
Staphylococcus
;
Staphylococcus aureus