Objective To understand patients' experience of intensive care with mechanical ventilation at intensive care units to provide a more holistic approach to patient care. Methods In-depth interviews were applied to 11 participants who survived from mechanical ventilation. The pa-tients were asked to describe their experience by responding to the research question "what is it like to experience mechanical ventilation treatment at an ICU?"The data were analyzed by Giorgi's ph e-nomenological procedures. Results Five mutually exclusive themes emerged, which were titled "be-ing in an unconventional environment", "suffering from physical discomfort", "encountering psycho-logical crisis", "self-encouragement", and"self-reflection". Conclusions Patients' experiences while receiving mechanical ventilation at an intensive unit were poignant and afeard, but "self-encour-age-ment" and "self-reflection" will enhance patients' self-confidence which will be beneficial for their re-covery of critical illness.

Objective　To study the application method,intensive monitoring and treatment to complication of mild hypothermia therapy for critically ill patients.Methods　 Apply mild hypothermia therapy to 19 critically ill patients along with baseline therapy.Results　The Glasgow evaluation scores of 18 living patients increase from average 6 to 11.6 a month later.Conclusion　Mild hypothermia therapy is an important treatment method for critically ill patients with coma.From the point view of nursing care,we assess the method of temperature decrease and recovery,usage of hibernation drugs,choice of temperature,intensive monitoring and treatment of complications.

0.05);group C is the lowest-cost treatment options and the most economical one.

ObjectiveTo explore the impact of urinary incontinence on women's quality of life, and the effective measures to improve it.MethodsWe conducted a comprehensive literature review to analyze the present research about quality of life on urinary incontinent women and interventions for improving it.ResultsUrinary incontinence influenced patients' quality of life in many aspects, especially in their physical health, mental health, daily living and sexual life. Regular pelvic floor muscle training could prevent and control the incontinence symptoms and improve patients' quality of life.ConclusionsIt is necessary to carry on a series of activities to propagandize that urinary incontinence can be treated, effective measures should be taken to prevent and manage urinary incontinence in order to improve quality of life in urinary incontinent women.

Objective To investigate the severity of cough in patients with different etiology of chronic cough and its related factors. Methods One hundred and fifty patients with chronic cough were recruited. The diagnosis of the patients was as follows: 24 cases with post nasal drip syndrome (PNDs), 26 cough variant asthma (CVA), 20 gastroesophageal reflux-induced cough (GERC), 31 eosinophilic bronchitis (EB), 30 atopic cough (AC) and 19 cough post infection (CPI). The severity of cough at daytime and night-time were scored by the doctor and the patient at the first visit. The correlation between cough score and age, gender and course duration of patients was analyzed. Results There was no significantly difference of cough score at daytime among different groups. Cough score at night in CVA group was significantly higher than that of other five groups (all P <0.01). Regression analysis showed that cough score at daytime was significantly correlated with age of patients (P < 0.05), while cough score at night was correlated significantly with gender (P < 0.01). Conclusion Cough severity at daytime in different etiology of chronic cough is similar, while that at night in patient with CVA is higher than that with other etiology.

Objective To descript the current situation and to analyze the impact factors of the stigma among the community women with urinary incontinence in Jinan.Methods This was a crosssectional survey by purposive sampling.506 women with urinary incontinence from 3 communities in Jinan were measured by the International Consultation on Incontinence Questionnaire-Short Form(ICIQ-SF) and the revised version of the Social Impact Scale(SIS)in order to get the information about the urinary incontinence type,severity degree and the stigma.Results The participants' total score of the SIS was (39.62±8.10) points and the score index was 55％.Score index of three subscale including social isolation,social exclusion and inner sense of shame were 58％,45％,70％; age and severity degree of urinary incontinence were independent factors and totally accounted for 14.0％ of the variance in stigma.Conclusions It suggested that,to make patients drop the cognitive errors about being incontinence,then decrease the stigma and improve the quality of life,the Health Care Sector should positively broadcast the relative knowledge of urinary incontinence and encourages patients to seek help,screen,diagnose,and get treatment earlier,and complete the tertiary prevention.

OBJECTIVE:To explore the effects of Cangfu daotan decoction on expression of organic anion transporting poly-peptide(oatp4a1)and level of sex hormone in the endometrium and ovary tissues of rats with obesity-type polycystic ovarian syn-drome(PCOS). METHODS:Obesity-type PCOS rat models were established. 50 rats were randomized into a normal control(iso-metric normal saline)group,a model(isometric normal saline)group,a metformin(0.043 g/kg)group and Cangfu daotan decoc-tion high-dose and low-dose [5.68 and 1.42 g(medicinal materials)/kg] groups. The rats were given drugs ig once a day for 14 con-secutive days. The expression of oatp4a1 protein in the endometrium and ovaries of the rats was determined by ECL and Western blot. The levels of luteinizing hormone(LH),follicle stimulating hormone(FSH),testosterone(T)and estradiol(E2)in rat’s se-rum were detected by ELISA. RESULTS:Compared to the normal control group,those in the model group had weaker expression of oatp4a1 protein in the endometrium and ovaries,higher levels of serum LH,LH/FSH and T,lower levels of serum FSH and E2. There were statistical significances(P<0.01). Compared to the model group,those in metformin group,Cangfu daotan decoction high-dose and low-dose group had higher expression of oatp4a1 protein in the endometrium and ovaries,lower levels of LH/FSH and T,higher levels of serum E2;those in metformin group and Cangfu daotan decoction high-dose group had lower levels of serum LH,higher levels of serum FSH. There were statistical significances(P<0.01 or P<0.05). CONCLUSIONS:Cangfu daotan decoc-tion can increase the expression of oatp4a1 in the endometrium and ovaries of obesity-type PCOS model rat,alleviate phlegmy dampness and regulate the level of sex hormone.

Objective To estimate help-seeking behavior among individual with overactive bladder (OAB) in type 2 diabetes mellitus and its influencing factors.Methods This was a cross-sectional survey with a representative sample of 133 patients with OAB in type 2 diabetes mellitus responded the questionnaires,including a self-designed Demographic Data Questionnaire,12-item Short-Form health survey questionnaire,Overactive Bladder Symptom Score,Patient Perception of Bladder Condition,Help-seeking Behavior Questionnaire.Results Among cases,21.8％(29/133) had seen a doctor for voiding problems.In the Logistic model,educational status,Charlson comorbidity index,glycosylated hemoglobin,and OAB symptom bother were found to be associated with help-seeking behavior,OR value(95％ confidence interval) were 3.158(1.511-6.599),2.537(1.327-4.849),0.631(0.430-0.926),1.655(1.126-2.434),P ＜0.01 or 0.05.Conclusions The help-seeking rate of OAB individuals in type 2 diabetes mellitus patients is low.Health care providers should understand the predictors of help-seeking behavior and take actions to improve patient's health care utilization and quality of life.

Objective To explore the status of toileting behavior and its relationship to lower urinary tract symptoms (LUTS) in female nurses. Methods A total of 636 nurses were selected from three top three hospitals in Jinan by multi-stage sampling. The nurses′toileting behavior and LUTS were assessed by Women′s Toileting Behavior Scale and The International Consultation on Incontinence Questionnaire-Female Lower Urinary Tract Symptoms. Univariate analysis and hierarchical regression analysis were conducted to examine the factors associated with LUTS. Results The nurse groups were widespread adverse toileting behavior. Delayed voiding was the most severe problem in nurses. Among LUTS storage symptoms were the most severe,voiding symptoms followed and incontinence symptoms were mild. Hierarchical regression analysis exhibited that factors associated significantly with LUTS included age, body mass index, menstrual status, working experience, history of urinary tract infection and poor toileting behavior (mainly hard urination, delayed voiding, and anuria urination),which explained 9.1%,12.9% and 12.6% of the variance of storage symptoms, voiding symptoms and incontinence symptoms, respectively. Conclusions Poor toileting behaviors are highly prevalent in nurses and they are closely related to LUTS, leading to concerns about possible effects of working environment and poor bladder habits on LUTS. Cognitive-behavioral intervention for this group is essential for delivering information about correct toileting behavior and its association with LUTS. Hospital administrators are suggested to pay more attention to nurses′working environment and its impact on nurses′health in order to improve their quality of life and job satisfaction.

Objectiev To explore the use of different nebulizer to establish mice model that have airway eosinophilic inflam -mation without airway hyperresponsiveness .Methods Female BALB/c mice were obtained and divided randomly into 3 groups:eo-sinophilic airway inflammation group ( experimental group ) , asthma group, and control group .Mice were immunized with ovalbumin ( OVA) .The experiment group and asthma group were challenged with an aerosol of 1% w/v OVA using a PARI TIA and PARI LC STAR nebulizer on day 28, 29, 30, respectively.The control mice were received saline sensitization and challenge .Airway respon-siveness was measured .Cell different counts in bronchial alveolus lavage fluid ( BALF) were performed and a pathologist performed histopathological evaluation of the trachea and lung .Results Airway responsiveness in the experimental group was not significantly different compared with the normal saline ( NS) group but was significantly different compared with the asthma group .Eosinophils in BALF were increased significantly in experimental group compared with the NS group , and significant difference was observed between experimental group and asthma group .The intensity of airway inflammation in experimental group was milder than that in the asthma model .Conclusions We established an eosinophilic bronchitis mice model without hyperresponsiveness successfully .Our model es-tablished a foundation for the further research in airway hyperresponsiveness .