1.Experimental study on the clearing stomach-heat effect of Stomach-Clearing Powder
Ke SUN ; Xiaodan ZHANG ; Ming YANG ; Xiaochen ZHANG ; Wenjua WANG
Chinese Traditional Patent Medicine 1992;0(06):-
AIM:To investigate the principle of function of Stomach-Clearing Powder (Radix Rehmanniae, Radix Angelicae Sinensis, Cortex Moutan Rhizoma Coptidis, etc.) on clearing the stomach-heat. METHODS: 5% alcohol water were used as drink water of mice to make model. In the treatment group, "Stomach-Clearing Powder" was administed. Three weeks later, the anal temperature, the evacuation time of active carbon powder,stomach cAMP, SOD, MDA and the pathological changes in stomach and tongue were observed and recorded. RESULTS: "Stomach-Clearing Powder" could can obviously improve the pathological changes of the model group with stomach-heat syndrom. CONCLUSION: The established pathological model of stomach-heat syndrome accorded with traditional Chinese medicine; "Stomach-Clearing Powder" has the effect on clearing the stomach-heat on the experimental mouse.
2.Application of Three-Dimensional Computed Tomography for Detecting Femoral Neck Anteversion in Development Dislocation of Hip in Children
ke, SUN ; sheng-ping, TANG ; jun-chang, QIN ; wei, YU ; jing-ming, HAN ; bao-ping, LIU
Journal of Applied Clinical Pediatrics 1986;0(02):-
Objective To evaluate the value of reconstruction of three-dimentional CT in development dislocation of hip(DDH)in children.Methods Twelve cases of DDH concluded 4 bilateral and 8 unilateral cases.To sum up,16 sick hips were operated and 8 normal hips were also obtained by three-dimensional CT(Hip speed Fi/x,GE Co).Results 3D reconstruction were used to show femoral head,(acetabulum) and relationship of acetabulum and femoral head respectively.The difference between FNA measurement of sick hips and those of normal hips were significant(P
3.Clinical Epidemiologic Studies on Children with Transient Synovitis of Hip
ke, SUN ; sheng-ping, TANG ; wei, YU ; bao-ping, LIU ; jing-ming, HAN ; jun-chang, QIN
Journal of Applied Clinical Pediatrics 1993;0(03):-
Objective To investigate the clinical epidemiologic features of transient synovitis(TS) of hip in children occurred in Shen-zhen district.Methods The medical files were reviewed and a standard questionnaire was filled according to the conditions of 705 cases such as pathogeny,clinical manifestation,therapy and prognosis.Results Transient synovitis occurred in a sporadic form all the year round.The peak age of patients with TS was 3-7 years old.The ratio of boys to girls was 2.9:1.About 19.3% patients were attacked an upper respiratory tract infection and 11.9% patients attributed the symptoms to trauma or severe activities before 1 week.A varying degree of painful limp and restriction of movement at the hip were found clinically.All of cases were cured by skin traction.The incidence of recurrence was 6.95%.Conclusions Male predominance is found in TS.It is characteristic of sporadic form in the 4 seasons and intently relation to an upper respiratory tract infection and trauma or severe activities.TS is recurrent and the prognosis is good by skin traction.
4.Recently identified renal cell carcinoma.
Ming ZHAO ; Xiao-dong TENG ; Ke SUN ; Liang CHENG
Chinese Journal of Pathology 2013;42(7):478-482
Adenocarcinoma, Follicular
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metabolism
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pathology
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Adenoma, Chromophobe
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metabolism
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pathology
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Adenoma, Oxyphilic
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metabolism
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pathology
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Angiomyoma
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metabolism
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pathology
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Biomarkers, Tumor
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metabolism
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Carcinoma, Papillary
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metabolism
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pathology
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Carcinoma, Renal Cell
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classification
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metabolism
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pathology
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ultrastructure
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Diagnosis, Differential
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Humans
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Kidney Neoplasms
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classification
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metabolism
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pathology
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ultrastructure
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Thyroid Neoplasms
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metabolism
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pathology
5.No-heparizated open operation at low costal arch in live donor nephrectomy via retroperitoneal approach
Zhongyu SONG ; Wenyong YUAN ; Qifa YE ; Yingzi MING ; Ke CHENG ; Shanqun CHEN ; Jianming SUN
Journal of Chinese Physician 2009;11(6):760-762
Objective To evaluate the possibility of no-beparin open operation at low costal arch in live donor nephrectomy via retroperitoneal approach. Methods The effects of 134 cases no-beparin operation and 82 eases heparinized operation at low costal arch in live donor nephrectomy via retroperitoneal approach during 2003.5 to 2008.5 in our hospital were retrospective analyzed. Results The kidneys of the donors in two groups were successfully harvested. The operation time varied from 110 rain to 200 rnin, and warm isebemia time varied from lOs to 20s. Delayed graft function (DGF) was oceurred in one ease in each group. There was no signifieant difference in live donor nephreetomy between the two groups(P >0. 05), but the no-beparin group had less bleeding. Conclusion The no-beparin open operation at low eostal arch in live donor nephrectomy via retroperitoneal approach is technieal]y feasible and safe, and has less bleeding, and little influence on the allograft.
6.Low-grade fever and generalized lymphadenopathy.
Zhao-ming WANG ; Ke SUN ; Yan-li WANG ; Hong-tian YAO
Chinese Journal of Pathology 2010;39(7):480-481
Anti-Bacterial Agents
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therapeutic use
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Antigens, CD20
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metabolism
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CD3 Complex
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metabolism
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CD4 Antigens
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metabolism
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Fever
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drug therapy
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virology
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Herpesvirus 6, Human
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isolation & purification
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Humans
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Lymph Nodes
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pathology
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virology
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Lymphadenitis
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drug therapy
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metabolism
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pathology
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virology
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Male
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Middle Aged
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Roseolovirus Infections
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drug therapy
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metabolism
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virology
8.Treatment of GartlandⅢ Supracondylar Fracture of Humerus in Children by Overhead of Olecranon Traction
ke, SUN ; sheng-ping, TANG ; wei, YU ; bao-ping, LIU ; jing-ming, HAN
Journal of Applied Clinical Pediatrics 2006;0(23):-
Objective To discuss the indication and complication of overhead traction of olecranon for displaced extension-type GartlandⅢ supracondylar fracture of the humerus in children.Methods Total of 87 patients(Gartland Ⅲ) proceeded with overhead skeletal traction of ulnar olecranon,including 68 cases of ulnar deviation and 19 cases of radial deviation.Eighteen cases had complicating revolve deviation.According portable X-ray results in the 2nd and 5th,three-dimension adjustment was performed within 1 week.Five patients were treated by open reduction because of symptoms nerves and blood vessel compression.When X-ray examination showed good callus formation and stable reduction,the patient was discharged after the elbow was stabilized in flexion position with plaster fixation,which was removed in 2 weeks.Results Sixty-seven of 87 patients were followed-up for 18 months.All of them had excellent results except one who had permanent ulnar nerve injury.No cubitus varus was observed.Conclusions The overhead olecranon skeletal traction is a simple,effective method,because it can increase joint motion,relieve elbow swell and pain rapidly,and improve upper limb line of traction.However,open reduction shall be done promptly if there is evidence of nerve,blood vessel or soft tissue between broken ends of fractured bone within 5 days.
9.Treatment of the complications of polyacrylamide hydrogel injection for augmentation mammaplasty.
Bao-dong SUN ; Qun QIAO ; Ying YUE ; Ru ZHAO ; Jia-ming SUN ; Ke-ming QI
Chinese Journal of Plastic Surgery 2004;20(3):200-202
OBJECTIVEThe purpose of this study was to search for a perfect treatment for the complications after polyacrylamide hydrogel injection for augmentation mammaplasty.
METHODS48 patients who accepted polyacrylamide hydrogel injection for augmentation mammaplasty were included in this study. Operations were performed for the complications of polyacrylamide hydrogel injection. The clinical data were analyzed and the experience in the treatment of the complications was summarized.
RESULTSAll patients were satisfied with the result of the operation. The B-ultrasonic examination showed that no visible polyacrylamide hydrogel remained in the cavity.
CONCLUSIONThe best therapy for the complications of polyacrylamide hydrogel injection was removing of the polyacrylamide hydrogel and the pathologic tissue and irrigation of the cavity.
Acrylic Resins ; administration & dosage ; Adult ; Female ; Humans ; Infection ; etiology ; surgery ; Injections ; Mammaplasty ; adverse effects ; methods ; Pain ; etiology ; surgery ; Postoperative Care ; Postoperative Complications ; etiology ; surgery ; Surgical Procedures, Operative ; standards ; Treatment Outcome
10.Leptin receptor of the hind brain nuclei is involved in the conditioned taste preference of rats.
Cai-xia LIN ; Shao-yun ZHANG ; Ke CHEN ; Xiao LUO ; Bo SUN ; Yu-ming KANG ; Jian-qun YAN
Chinese Journal of Applied Physiology 2015;31(6):549-555
OBJECTIVEConditioned taste preference (CTP) is a taste learning reflex by which an animal learns to prefer a substance which tastes not well and has been studied with much interest in recent years. However, the neural substrates of CTP are less known. This study aimed to determine the possible neural path- ways of CTP and whether serum leptin level and the leptin receptor (OB-Rb) in the hind brain are involved following CTP formation.
METHODSWe established CTP of quinine in rats with a 2-bottle preference test. The serum leptin concentrations were detected, the expression of c-fos in the rat brain was tested to determine the nuclei in relation with establishment of CTR Finally, the OB-Rb mRNA expression was examined by RT-qPCR assay in parabrachial nucleus (PBN) and the nucleus of the solitary tract (NST) of the hind brain.
RESULTSCompared with control group, the level of serum leptin was higher in the CTP group (4.58 ± 0.52 vs 1.67 ± 0.25 µg/L, P < 0.01); increased c-fos positive cells were found in the anterior hypothalamus (AH, 221.75 ± 4.96 vs. 178.50 ± 6.63 cells/mm², P < 0.05), the basal lateral amygdala (BLA, 70.75 ± 6.17 vs 56.50 ± 3.62 cells/ mm², P < 0.05) and the nucleus of the solitary tract (NST, 41.25 ± 1.32 vs 32.50 ± 1.02 cells/mm², P < 0.05). But in ventromedial nucleus of the hypothalamus (VMH, 20.75 ± 2.73 vs 38.5 ± 1.54 per 1 mm², P < 005), PBN (21.50 ± 2.24 vs 36.25 ± 1.49 cells/mm², P < 0.05) and the central nucleus of the amygdala (CeA, 22.25 ± 1.53 vs 35.50 ± 2.11 cells/mm², P < 0.05), the number of c-fos positive cells was decreased in the CTP group. In addition, we found OB-Rb mRNA expression in PBN of CTP group rats was higher than that of control group (0.95 ± 0.055 vs 0.57 ± 0.034, P < 0.05), while there was no significant difference of OB-Rb mRNA expression in NST between the two groups.
CONCLUSIONNuclei AH, BLA, NST, VMH, PBN and CeA participate in the formation of CTP. Leptin and its receptor in PBN may be involved in the formation and maintenance of CTP.
Animals ; Conditioning (Psychology) ; Leptin ; blood ; Rats ; Receptors, Leptin ; physiology ; Rhombencephalon ; physiology ; Taste ; physiology