1.Clinical studies of liver cirrhosis with special reference to its etiology and prognosis.
Akihiko YUMINO ; Koichi YAMASHITA ; Shigefumi SHIMIZU ; Koji ISOMURA ; Shusuke NATSUKAWA ; Kazuyoshi ONISHI ; Shigenobu TERASHIMA ; Shinji SASAKI
Journal of the Japanese Association of Rural Medicine 1986;35(4):755-764
A total of 194 cases of liver cirrhosis, which had been treated in our hospital during the past 5 years, were calssified by the causes into the following four groups:(I) hepatitis B virus, (II) alcoholic, (III) special origins, and (IV) reasons unknown. They each accounted for 23.2%, 35.6%, 1.5% and 39.7%, of the total.
Their clinical features and prognosis were examined. To be noted is the finding that many patients in group IV had had blood transfusions. This suggests that non A non B hepatitis viruses might be involved in the occurrence of the liver disease. On the whole, the five-year survival rate was 45.6%. There was not any significant difference among the four groups. However, prognoses were poor in groups II, I and IV, in that order.
As regards the cause of death, rupture of esophageal varice and hepatic failure showed a gradual decline, but complications of hepatocellular carcinomas sharply increased. Especially, in group I, this mortality was as high as 31.1%.
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