The effects of the serum vitamin C levels on the activity and isozyme pattern of serum lactate dehydrogenase (LDH) in males and females in their middle and old age were examined.
There was no siginificant correlation among the total serum, LDH activity and serum vitamin C levels in the 87 male and 83 female ranging from 45 to 84 years of age. However, high inverse correlations were found among the percentage of LDH-4 and LDH-5 and serum vitamin C levels all of age groups (45-59 years of age group, 60-69 years of age group and over 70 years of age group) of males and females.
These results suggest that the percentage of LDH-4 and LDH-5 are influenced by the vitamin C intake in males and females in their middle and old age.

In search of a better primary treatment of acute boric acid poisoning, the adsorption capacity of boric acid onto activated carbon as an antidote was investigated in vitro.
Wide differences in the amount of boric acid adsorbed were recognized depending on individual activated carbons. In order to elucidate the dominant factor in boric acid adsorption, correlations between the properties of activated carbon and the amounts of boric acid adsorbed are discussed. A significant correlation was recognized between the surface pH of activated carbon and the amount of boric acid adsorbed in low equilibrium concentration. It is assumed that the surface pH of activated carbon is a chief factor affecting the amount of boric acid adsorbed.

The effects of the food intake pattern on the activity and fraction pattern of serum γ-glutamyl transpeptidase (γ-GTP) were examined in 257 healthy Japanese men.
Applying the technique of factor analysis to the food intake data, the following three factors were extracted. The first factor (F1): meats, eggs, and vegetables had a highly positive factor loading. The second factor (F2): wheat had a highly positive factor loading, while rice had a highly negative factor loading. This factor was considered to be a “wheat versus rice factor”. The third factor (F3) could not be explained simply in terms of its factor. The scores of the first two factors for the 257 subjects were calculated.
Significantly negative correlations were observed between the percentage of GT₁ fraction and the factor score of F1 (r=-0.230, p<0.01), between the percentage of GT₁ fraction and the factor score of F2 (r=-0.187, p<0.01). The total serum γ-GTP activity was not correlated with the factor score. These results suggested that the percentage of GT₁ fraction is influenced by the pattern of food intake.

The relationship between serum creatine phosphokinase (CPK) activity and labor strength was examined.
Our epidemiological study showed thar the serum CPK activity in a group of men who worked over ten hours was significantly higher than that in the other groups who worked less than ten hours. In women, the serum CPK activity in a group who worked over seven hours was significantly higher than that in the other groups. The serum CPK activity in fishermen was significantly higher than that in those engaged in other than fishery.
In a laboratory study, test subjects were divided into 3 groups to perform 3 types (30%, 50%, 70% of VO_2max) of exercise for 6 weeks. A rise in the serum CPK activity was noted in every group during exercise. The mean increase for these groups were 44.0 %, 48.1 % and 67.9 %, respectively.

The effect of daily physical activity on the serum lipid level was examined. This study consisted of two parts, an epidemiological study and a laboratory study.
In the epidemiological study, we investigated the relationship between serum lipids and energy expenditure in young adults females. Significant correlations were found between energy expenditure/body weight and the levels of serum HDL-cholesterol and serum triglyceride, and atherogenic index.
In the laboratory study, we examined the effects of exercise on the serum lipid level. Groups of subjects took part in the programs of physical activity of two different intensities for 6 weeks, and their serum lipid levels before and after these programs were compared. Exercise regimens of increasing intensity caused a significant mean increase in the serum HDL-cholesterol level. However, these regimens did not cause any significant change in serum total cholesterol and serum triglyceride values.
These results suggest that doing even light exercise on a regular basis is effective in producing an optimum serum lipid pattern in young adult females.

For the evaluation on the efficacy of activated charcoal as an antidote in acute diquat poisoning, the adsorption characteristics of diquat in distilled water and in physiological saline solution were investigated.
The amount of diquat adsorbed onto activated charcoal in physiological saline solution was larger than that in distilled water. The enhancing effect of sodium chloride on diquat removal by activated charcoal was observed.
The adsorption rate of diquat onto activated charcoal was also enhanced by the addition of saline. The correlations between the adsorptivity for diquat and properties of activated charcoal were not significant.
These results suggest that the increase of adsorptivity of activated charcoal for diquat might be due to the increase in electrostatic interaction between the surface on which an electrical double layer was formed by saline and diquat.