There are few scientific papers about the effectiveness of the laughter of the patients, even laughter is essential to human communication. Cultural values of people acknowledge laughter as good medicine, although the black humor is sometimes risky strategy for the depressed patient. The most patient has his own serious problem which prevent him to laugh. Laughter in complementary and alternative medicine means to offer the atmosphere and environment where depressed patient can be educated smile and laugher to improve psycho-physiological status.
Current review of laughter was done and grouped into three main themes: (1) medical aspect of laughter, (2) laughter as one of the alternative medicine, which relieve stress, care and heal the patient and (3) the laughing therapist who enhancing laughing to the patients suffered from mental status. There are some supported paper of a connection between sense of humor and self-reported physical health. More research is required to determine interrelationships between sense of humor and well-being. This study contribute the value and significance of laughter to support people in their learning journey.

Objective: The purpose of this research was to assess healthy people’s psychological and physical changes when spending time in an green area in the middle of the urban square.
Method: 10 subjects (20–26 years old) were asked to remain for one hour in a green area area in the JR Akihabara station square, in the middle of the urban square, on a sunny September morning. 10 other control subjects were asked to remain in a tent erected near the green area which was positioned so that the participants could not see the green area.
Results: Participants in the green area showed a reduced Profile of Mood State (POMS) for anger-hostility (p<.01), whereas control participants showed no significant change on the same test. Furthermore, subjects in the green area showed either positive results or no change using Wartegg Zeichen Test, whereas control subjects showed negative scoring (p<0.05). Recorded quantities of salivary cortisol of subjects in the green area also reduced.
Conclusion: Green areas in the center of busy towns have a positive effect on health psychologicaly and physiologicaly. These results were obtained from a study commissioned by the Ministry of Land, Infrastructure and Transport and undertaken by the Organization for Landscape and Urban Greenery Technology Development in which the author participated.

The methodology of AIDS education for the yourth is extremely important. AIDS Peer Education was given to nursing students by AIDS Peer Educators (APE), trained and certified by the Stop AIDS Campaign Committee of the Japan Hospital Association. The APEs are 18-to 21-year-old medical or nursing students.
Posteducational questionnaires were distributed and analyzed. One hundred fifty-five students (92.6%) replied. According to the survey, students found the learning method extremely attractive and felt sympathy toward patients with AIDS. More than 60 % of students felt a change in attitude about AIDS. The effect of the education using APEs was remarkable.