1.Routine diabetes screening in blood donation campaigns
Samad Nor A’zian ; Yong Pei Wen ; Mahendran Kauthaman
The Malaysian Journal of Pathology 2015;37(2):137-140
Background: Data from the National Health and Morbidity Survey 2011 showed that 20.8% of
Malaysians above 30 years have diabetes. 10.1%of them are undiagnosed. Mobile blood drives could
complement the public health department efforts in diabetes screening for early detection of the
illness. Aims: This study aims to determine the necessity of diabetes screening as a routine screening
program during blood donation campaign. Methods and Material: Blood donation campaigns which
involved the public community between January 2013 and June 2013 were included in this study.
Donors above 30-years-old, not known to have diabetes, consented for diabetes screening. Diabetes
screening was done by checking random capillary blood sugar (RCBS) levels while performing a
Hemoglobin test and ABO grouping. Donors with RCBS of ≥7.8 mmol/L were given appointments
for oral glucose tolerance test (OGTT) to confirm the diagnosis of diabetes. Results: A total of 211
diabetes screenings were performed. Mean RCBS was 6mmol/L. 43(20.4%) donors had RCBS≥
7.8mmol/L. 10 donors were later diagnosed to have diabetes (5.0%) and 5 donors were prediabetes
(2.5%). 9 donors (4.3%) did not turn up for further investigation. Conclusions: Blood donors are
expected to be healthy volunteers. The diabetes prevalence among blood donors (5.0%) is considered
low if compared with the prevalence in the whole population (20.8%). However, the number is largely
comparable to the prevalence of undiagnosed diabetes in the country (10.1%). Routine diabetes
screening during blood donation campaign should be implemented to safeguard donors’ health and
serve as a public health initiative to improve community health.
2.Clinical characteristics, treatment and 2-year outcomes in Malaysian and Bruneian patients with stable coronary artery within the worldwide CLARIFY registry
Kok Han Chee ; Gim Hooi Choo ; Ahmad Nizar Jamaluddin ; Kauthaman Mahendran ; Nicola Greenlaw ; Chandran Krishnan
The Medical Journal of Malaysia 2017;72(5):282-285
Introduction: The on-going, international, prospective,
observational, longitudinal CLARIFY registry is investigating
the demographics, clinical profiles, management and
outcomes of patients with stable coronary artery disease
(CAD). This paper assesses baseline characteristics,
treatment, and clinical outcomes at two years’ follow-up of
Malaysian/Bruneian patients compared with the overall
registry population.
Method: Between November 2009 and July 2010, outpatients
from 45 countries who met the criteria for stable CAD were
recruited into the registry. Baseline characteristics were
documented at enrolment, and patients were reassessed
during their annual visits over a five-year follow-up period.
Key outcomes measured were sudden death and
cardiovascular (CV) death, non-CV death and CV morbidity.
Results: At baseline, 33,283 patients were available for
analysis within the registry; 380 and 27 were Malaysians and
Bruneians, respectively. The mean ages of
Malaysian/Bruneian patients and the rest of the world (RoW)
were 57.83 ±9.98 years and 64.23 ± 10.46 years, respectively
(p<0.001). The median body mass index values were 26.6
(24.4-29.6) kg/m2 and 27.3 (24.8-30.3) kg/m2
, respectively
(p=0.014). Malaysian/Bruneian patients had lower rates of
myocardial infarction (54.55% versus 59.76%, p=0.033) and
higher rates of diabetes (43.24% versus 28.99%, p<0.001)
and dyslipidaemia (90.42% versus 74.66%, p<0.001)
compared with the RoW. Measured clinical outcomes in
Malaysian and Bruneian patients at 2-years follow-up were
low and generally comparable to the RoW.
Conclusion: Malaysian/Bruneian patients with stable CAD
tend to be younger with poorer diabetic control compared
with the RoW. However, they had similar outcomes as the
main registry following two years of treatment.
Coronary Artery Disease
;
Cardiovascular Diseases
;
Heart Rate