1.Robotic-Assisted Thyroidectomy: A New Experience in Anaesthesia
Mardhiah Sarah HM ; Adlin Dasima AK ; Nadia Hanom I ; Siti Aznida AK ; Rusnaini MK ; Mohd Fahmi Z ; Mohd Nazir MS ; Izwah Azyyati A ; Mohd Firdaus S ; Karis M
Journal of Surgical Academia 2017;7(1):51-54
This is our first experience in providing general anaesthesia for robotic-assisted thyroidectomy (RAT). It is rather a
new experience for our anaesthetic team and few issues should be addressed. The conduct of RAT must be fully
understood and familiarized as it may present with few challenges for the anaesthesiologists. The key point of
success during this learning curve period is the importance of teamwork between the anaesthesiologists and the
operating surgeons. The specific anaesthetic challenges include limited access to the patient post-docking of the
robot, the need of extra precautions of the anaesthetic circuit and IV line connections, a vigilant anaesthesiologists
and options for postoperative pain relief.
Thyroidectomy
2.Genomic surveillance of Neisseria gonorrhoeae in the Philippines, 2013–2014
Manuel C Jamoralin, Jr ; Silvia Argimon ; Marietta L Lagrada ; Alfred S Villamin ; Melissa L Masim ; June M Gayeta ; Karis D Boehme ; Agnettah M Olorosa ; Sonia B Sia ; Charmian M Hufano ; Victoria Cohen ; Lara T Hernandez ; Benjamin Jeffrey ; Khalil Abudahab ; John Stelling ; Matthew T. G Holden ; David M Aanensen ; Celia C Carlos
Western Pacific Surveillance and Response 2021;12(1):17-25
Antimicrobial-resistant Neisseria gonorrhoeae is a major threat to public health and is of particular concern in the Western Pacific Region, where the incidence of gonorrhoea is high. The Antimicrobial Resistance Surveillance Program (ARSP) has been capturing information on resistant gonorrhoea since 1996, but genomic epidemiology studies on this pathogen are lacking in the Philippines.
We sequenced the whole genomes of 21 N. gonorrhoeae isolates collected in 2013–2014 by ARSP. The multilocus sequence type, multiantigen sequence type, presence of determinants of antimicrobial resistance and relatedness among the isolates were all derived from the sequence data. The concordance between phenotypic and genotypic resistance was also determined.
Ten of 21 isolates were resistant to penicillin, ciprofloxacin and tetracycline, due mainly to the presence of the blaTEM gene, the S91F mutation in the gyrA gene and the tetM gene, respectively. None of the isolates was resistant to ceftriaxone or cefixime. The concordance between phenotypic and genotypic resistance was 92.38% overall for five antibiotics in four classes. Despite the small number of isolates studied, they were genetically diverse, as shown by the sequence types, the N. gonorrhoeae multiantigen sequence typing types and the tree. Comparison with global genomes placed the Philippine genomes within global lineage A and led to the identification of an international transmission route.
This first genomic survey of N. gonorrhoeae isolates collected by ARSP will be used to contextualize prospective surveillance. It highlights the importance of genomic surveillance in the Western Pacific and other endemic regions for understanding the spread of drug-resistant gonorrhoea worldwide.