1.Sacrectomy of Primary Sacral Bone Tumor and Reconstruction With Internal Fixation
Renjie LI ; Qiang LI ; Kanghua LI
Journal of Chinese Physician 2001;0(06):-
Objective To study the methods for reconstruction of pelvic ring after subtotal sacrectomy of primary sacral bone tumor.Methods The pelvic ring of nine patients with primary sacral bone tumor were reconstructed by internal fixation after sacrectomy.Results In 9 patients,all were followed-up and got satisfactory functional recovery, the pelvic ring was stable without dislocation.Conclusions Operation should be considered and adopted for primary sacral bone tumor. Reconstruction of sacrum with internal fixation can improve the stability of the pelvis.
2.Treatment of Distal Femoral Fractures With Sustain Plate
Renjie LI ; Qiang LI ; Kanghua LI
Journal of Chinese Physician 2001;0(08):-
Objective To study the methods for treatment of distal femoral complicated fractures.Methods Twenty-seven cases were treated using condyle sustain plate after open reduction.Results In 27 patients,all were followed-up for average 1 5 years,complications included two cases of phocomelia and another two patients with valgus deformity.According to Merchan standards,the rate of the excellent and the good was 73 9%.Conclusion Sustain plate is an excellent alternative for the treatment of distal femoral supracondylar fracture and intercondylar comminuted fracture.
3.Design of static three dimensional nail-plate system and comparative biomechanicai study in fixing femoral neck fracture
Guangcan LI ; Kanghua LI ; Bo WEI
Orthopedic Journal of China 2006;0(22):-
[Objective]Design the Static Three Dimensional Screw-Plate system(STDSP), bring a new instrument for the treatment of femoral neck fractures, which has good biome chanical features of axial loading and rotation stability and can reestablish the loss of support of the posterior neck of fracture with posterior comminution. [Method]Design the STDSP. To the fracture group,one femur of each pair was randomly selected to be stabilized by STDSP, and the other was fixed by the three cancellous lag screws(TCS). Then the constructions were tested with axial loading or rotation to failure. The intact group were fixed and then taken out with the two methods, then tested with axial loading. [Result] (1)Rotation test: Compare the loads of the same rotation angle and the loads of the same width the anterior gap of the osteotomy open, STDS group is bigger than TCS group(PTCS group (P
4.Lumbar discogenic low back pain treated with posterior lumbar interbody fusion and transpedicular instrumentation
Zhaohui HU ; Kanghua LI ; Bing LI
Orthopedic Journal of China 2006;0(17):-
[Objective]To explore the curative effect of lumbar discogenic low back pain treated with posterior lumbar interbody fusion(PLIF)and transpadicular instrumentation.[Method]Thirty-six patients with lumbar discogenic low back pain were treated with disc excision,lumbar interbody fusion and transpedicular instrumentation.The clinical results were evaluated by pre-and post-operative VAS(visual analogue scale),and the fusion rates were evaluated by X-ray of the lumbosacral spine.[Result]The average period of follow-up was 16 months,ranging from 8 to 28 months.Low back pain basically disappeared in 33 patients treated with PLIF,mild back pain occurred in 3 patients;the VAS after operation decreased significantly in comparison with that of preoparation(P
5.The study of the mechanism of resorpt ion of herniated disc tissue
Jing LI ; Jiangnan ZHOU ; Kanghua LI
Chinese Journal of Orthopaedics 2001;0(06):-
0.05).There were significant differences between group B and C pre and postoperatively(P
6.Study on in vitro nitric oxide and interleukin-6 levels Induced from peripheral Mononuclear cells in patients with osteosarcoma
Tao XIAO ; Jianzhen FANG ; Kanghua LI
Journal of Central South University(Medical Sciences) 2001;26(2):139-140
Peripheral blood mononuclear cells from 32 cases of osteosarcoma and 20 normal controls were separated and induced by lipopolysaccharide, followed by 48 hour incubation in vitro, then the supernatant were collected. The levels of IL-6 were measured by enzyme linked immunosorbent assays, the concentrations of NO were measured by Griess methods. The results were as follows: The concentrations of IL-6 and NO were significantly higher than those in normal contrls (P<0.01). There were positive correlation between the levels of IL-6 and NO in patients with osteosarcoma (r=0.652, P<0.01). The results suggest that the immune function of peripheral mononuclear cell in patients with osteosarcoma was disordered. It may activate peripheral mononuclear cells to produce high levels of IL-6 and NO, which may take part in the pathogenesis of osteosarcoma.
7.Relationship Between Vascular Endothelial Growth Factor Expression and Microvessel Density and Lung Metastasis in Osteosarcomas
Weidong SHEN ; Kanghua LI ; Hui ZHENG
Journal of Chinese Physician 2000;0(12):-
0 05), but was closely correlated to lung metastasis (P
8.A Small Anterior Incision Applied to Single Lumbar Segment Artificial Disc Replacement
Kanghua LI ; Feiyue LIN ; Yihe HU
Journal of Chinese Physician 2001;0(02):-
Objectives To introduce a small incision of anterior extraperitoneal approach to the lumbar spine for single lumbar segment artificial disc replacement. Methods Nine patients suffered from single segment herniation of lumbar intervertebral disc underwent operation of artificial disc replacement. The approach of this operation was with a small incision through medial of left sheath of rectums and access to the retroperitoneal region through extraperitoneal appearance. The clinical and surgical data including the length of incision, length of operation, blood lose, effect and complication of operation were analyzed retrospectively in these 9 patients.Results The average length of incision,time of operation and blood lose was 6 7cm, 150 minutes and 335ml, respectively. The clinical evaluation scales (the 5-point Likert scales for pain, function, economic status, and medication usage) showed great improvement after operation of these patients(P=0 008). No serious complication related with the approach was found. Conclusions The a small anterior incision through peritoneum of left rectus abdominis sheath and access to the retroperitoneal region through extraperitoneal, which can expose the region of lumbar segment from L3 to S1 sufficiently, is a safe and mini-lesion approach for single lumbar segment artificial disc replacement.
9.Treatment of Old Thoracolumbar Vertebrae Fractures and Dislocations With ZPLATE~(TM) Anterior Fixation Systems
Jianzhong HU ; Guanghua LEI ; Kanghua LI
Journal of Chinese Physician 2001;0(08):-
Objective To explore the efficacy of ZPLATE TM anterior fixation systems in the treatment of thoracolumbar fractures and dislocations.Methods 13 cases with old thoracolumbar fractures and dislocations accompanied with spinal cord injury have been treated by anterior decompression,implanting bone union and internal fixation with ZPLATE TM anterior fixation systems.Results After an average of 15 5 months followup,No plate and screw was loose and fragmentized,there is no pseudoarticulation formation,average union time are 3 7 months, and paraplegia showed different degrees of recovery.Conclusion It suggests that anterior approach provids thorough decompression and ZPLATE TM anterior fixation systems is a good spinal fixation system for the treatment of old thoracolumbar fractures and dislocations with the characteristics of strong fixation.
10.Establishment of finite element model of lumbar motion segments and its biomechanical significance
Kanghua LI ; Hua WANG ; Xiaoyuan HUANG
Chinese Journal of Tissue Engineering Research 2005;9(14):-
BACKGROUND: The commonly used research methods of lumbar biomechanics are animal model,physical model and corpse model respectively. However, each model has its own disadvantages.OBJECTIVE: To establish the finite element model of lumbarmotionsegments in order to provide theoretical basis for biomechanical research of lumbar.DESIGN: Single sample study based on healthy volunteer.SETTING: Orthopaedic department of a university hospital.PARTICIPANTS: The experiment was completed in the Orthopaedic Department of Xiangya Hospital of Central South University from December 2003to August 2004. A healthy male volunteer was chosen as a mock object.METHODS:CT scanning was conducted to the spine(T12 - S1) of a healthy volunteer by 2 mm layer and got 264 images. The 3D model of normal Chinese male L4 5 motion segments was built by combininglumbar images scanned by CT and anatomic data through 3DSMAX software. Then it was transferred into finite elementmodel by finite element analyzing software SAP2000.MAIN OUTCOME MEASURES: ① Vertebral body model andintervertebraldisc model built by 3DSMAX software; ② Finite element model of motion segment made by SAP2000 software.RESULTS:The finite element model of lumbar L4-5 segments had been built. It had totally 2 120 nodes that include 1 728 Solid units, 592 Area units and 50 Link units.CONCLUSION: The finite element model of lumbar motion segments can be established through CT scanning, digital image processing and computer aid design to further study the biomechanics of spine.