Objective To study the methods for reconstruction of pelvic ring after subtotal sacrectomy of primary sacral bone tumor.Methods The pelvic ring of nine patients with primary sacral bone tumor were reconstructed by internal fixation after sacrectomy.Results In 9 patients,all were followed-up and got satisfactory functional recovery, the pelvic ring was stable without dislocation.Conclusions Operation should be considered and adopted for primary sacral bone tumor. Reconstruction of sacrum with internal fixation can improve the stability of the pelvis.

Objective To study the methods for treatment of distal femoral complicated fractures.Methods Twenty-seven cases were treated using condyle sustain plate after open reduction.Results In 27 patients,all were followed-up for average 1 5 years,complications included two cases of phocomelia and another two patients with valgus deformity.According to Merchan standards,the rate of the excellent and the good was 73 9%.Conclusion Sustain plate is an excellent alternative for the treatment of distal femoral supracondylar fracture and intercondylar comminuted fracture.

0.05).There were significant differences between group B and C pre and postoperatively(P

[Objective]Design the Static Three Dimensional Screw-Plate system(STDSP), bring a new instrument for the treatment of femoral neck fractures, which has good biome chanical features of axial loading and rotation stability and can reestablish the loss of support of the posterior neck of fracture with posterior comminution. [Method]Design the STDSP. To the fracture group,one femur of each pair was randomly selected to be stabilized by STDSP, and the other was fixed by the three cancellous lag screws(TCS). Then the constructions were tested with axial loading or rotation to failure. The intact group were fixed and then taken out with the two methods, then tested with axial loading. [Result] (1)Rotation test: Compare the loads of the same rotation angle and the loads of the same width the anterior gap of the osteotomy open, STDS group is bigger than TCS group(PTCS group (P

[Objective]To explore the curative effect of lumbar discogenic low back pain treated with posterior lumbar interbody fusion(PLIF)and transpadicular instrumentation.[Method]Thirty-six patients with lumbar discogenic low back pain were treated with disc excision,lumbar interbody fusion and transpedicular instrumentation.The clinical results were evaluated by pre-and post-operative VAS(visual analogue scale),and the fusion rates were evaluated by X-ray of the lumbosacral spine.[Result]The average period of follow-up was 16 months,ranging from 8 to 28 months.Low back pain basically disappeared in 33 patients treated with PLIF,mild back pain occurred in 3 patients;the VAS after operation decreased significantly in comparison with that of preoparation(P

Peripheral blood mononuclear cells from 32 cases of osteosarcoma and 20 normal controls were separated and induced by lipopolysaccharide, followed by 48 hour incubation in vitro, then the supernatant were collected. The levels of IL-6 were measured by enzyme linked immunosorbent assays, the concentrations of NO were measured by Griess methods. The results were as follows: The concentrations of IL-6 and NO were significantly higher than those in normal contrls (P<0.01). There were positive correlation between the levels of IL-6 and NO in patients with osteosarcoma (r=0.652, P<0.01). The results suggest that the immune function of peripheral mononuclear cell in patients with osteosarcoma was disordered. It may activate peripheral mononuclear cells to produce high levels of IL-6 and NO, which may take part in the pathogenesis of osteosarcoma.

Objective To explore the efficacy of ZPLATE TM anterior fixation systems in the treatment of thoracolumbar fractures and dislocations.Methods 13 cases with old thoracolumbar fractures and dislocations accompanied with spinal cord injury have been treated by anterior decompression,implanting bone union and internal fixation with ZPLATE TM anterior fixation systems.Results After an average of 15 5 months followup,No plate and screw was loose and fragmentized,there is no pseudoarticulation formation,average union time are 3 7 months, and paraplegia showed different degrees of recovery.Conclusion It suggests that anterior approach provids thorough decompression and ZPLATE TM anterior fixation systems is a good spinal fixation system for the treatment of old thoracolumbar fractures and dislocations with the characteristics of strong fixation.

Objective To investigate the effects of 1,25-dihydroxyvitamin D_3 on the bone metabolism of primary osteoporosis.Methods Female New Zealand white rabbits aged 8 months were ovariectomized bilaterally as models of postmenopausal osteoporosis and they were randomly divided into 4 groups: pseudo-ovariectomized group(Sham group),ovariectomized group(OVX group),calcii gluconas group(OC group),calcii gluconas and 1,25-dihydroxyvitamin D_3 group(OCR group).Both female New Zealand white rabbits aged 3 years and male New Zealand white rabbits aged 4 years were selected as models of senile osteoporosis.They were randomly divided into 3 groups:control group,calcii gluconas group(Calcium group),calcii gluconas and 1,25-dihydroxyvitamin D_3 group(CR group).Rabbits in OC group and Calcium group were given calcii gluconas and in OCR group and CR group were given calcii gluconas and 1,25-dihydroxyvitamin D_3.The bone metabolic biochemical indexes were determined among all the experimental animals after they were given drug for 8 weeks.Results After the experimental animals were given drug for 8 weeks,the serum calcium(Ca),serum phosphorus(P) and alkaline phosphatase(ALP) of OCR group were significantly higher than those of OVX group and OC group(all P

[Objective]To evaluate the short-term and long-term effectiveness of the surgical technique of one-stage one-step surgical techniques of Z-plate-Ⅱ~(TM) internal fixation apparatus system and anterior debridement and autograft bone graft fusion in the treatment thoraco-lumbar spinal tuberculosis with kyphotic deformity.[Method]The outcome of sixty eight cases suffered from thoraco-lumbar spinal tuberculasis with kyphotic deformity between July 1998 and March 2004 managed by the surgical techniques of Z-plate-Ⅱ~(TM) internal fixation apparatus system and anterior debridement and antograft bone graft fusion through posteroiateral costotransversectomy or kidney incision was analyzed.All cases wer given a longitudinal study follow-up for a mean of 3.3(2.2~6.3)years postoperatively.[Result]All patients showed successful autograft bone graft fusion.Among 45 cases accompanied with neurotic symptom of Potts paraplegia,25 were completely recovered,15 were partly recovered,total the ratio of recovery was 88.89% at the end of postoperative follow-up.The average immediate postoperative correction of kyphosis angle was 28.9?,the average loss of correction was only 2.7? at final follow-up.[Conclusion]The surgical technique of one-stage one-step Z-plate-Ⅱ~(TM) internal fixation apparatus system and anterior debrideraent and autograft bone graft fusion is found helpful in strengthening the stability of the spine in thoraco-lumbar spinal tuberculosis with kyphotic deformity,providing successful interbody fusion and recovery of Potts paraplegia,correcting the kyphosis,and preventing progress of kyphosis.

BACKGROUND: The commonly used research methods of lumbar biomechanics are animal model,physical model and corpse model respectively. However, each model has its own disadvantages.OBJECTIVE: To establish the finite element model of lumbarmotionsegments in order to provide theoretical basis for biomechanical research of lumbar.DESIGN: Single sample study based on healthy volunteer.SETTING: Orthopaedic department of a university hospital.PARTICIPANTS: The experiment was completed in the Orthopaedic Department of Xiangya Hospital of Central South University from December 2003to August 2004. A healthy male volunteer was chosen as a mock object.METHODS:CT scanning was conducted to the spine(T12 - S1) of a healthy volunteer by 2 mm layer and got 264 images. The 3D model of normal Chinese male L4 5 motion segments was built by combininglumbar images scanned by CT and anatomic data through 3DSMAX software. Then it was transferred into finite elementmodel by finite element analyzing software SAP2000.MAIN OUTCOME MEASURES: ① Vertebral body model andintervertebraldisc model built by 3DSMAX software; ② Finite element model of motion segment made by SAP2000 software.RESULTS:The finite element model of lumbar L4-5 segments had been built. It had totally 2 120 nodes that include 1 728 Solid units, 592 Area units and 50 Link units.CONCLUSION: The finite element model of lumbar motion segments can be established through CT scanning, digital image processing and computer aid design to further study the biomechanics of spine.