1.The relationship between the food restriction and the formation of experimental 8astric ulcer
Chinese Journal of Pathophysiology 1986;0(01):-
On the basis of Shay's ulcer model, we have studied the effects of food re. striction time on the experimental gastric ulcer in rats. The results indicat that each restricted group forms gastric ulcer after ligation of pylorus 18 hr. There are a postive correlation between the restricted time and the severity of gastric ulcer, and a negative correlation between the severity of gastric ulcer and the amount of gastric acid secretion. We suggested that Shay's ulcer model does not belong to peptic ulcer, but belonges to one of the stress ulcers. The restricted time may play an important role in the mechanism for this ulcer model.
2.Coexistence of Hashimoto′s thyroiditis and subacute thyroiditis: report of two cases
Chinese Journal of Endocrinology and Metabolism 1985;0(02):-
Two unusual cases of coexistence of Hashimoto′s thyroiditis and subacute thyroiditis were reported. The diagnosis was based on the comprehensive analysis of clinical symptoms, laboratory data and histological findings. If patients with confirmed evidence of subacute thyroiditis were accompanied with markedly and persistently elevated titers of thyroid autoantibodies, coexistence of both diseases should be suspected.
3.A Multilevel Analysis on Influential Factors of Cognitive Change among Chinese Oldest-old
Wei-Ning YI ; Xiao-Ping KANG ;
Chinese Mental Health Journal 2002;0(07):-
Objective:To explore the influential factors of cognitive change among Chinese oldest-old.Method: Three waves of data from the Chinese Longitudinal Healthy Longevity Survey(CLHLS)were analyzed with a two-level repeated measures model.Results:In baseline,the male had a higher mean MMSE score than the female(27.0?3.7/24.4?5.6,P
4.New approach to action and biosynthesis of AngII and on it research
Nan ZHANG ; Yi KANG ; Jianshi LOU
Chinese Journal of Clinical Pharmacology and Therapeutics 2004;0(07):-
Renin-angiotensin system (RAS) is correlative with many diseases. Angio tensin II (AngII) plays an important role as the final effective approach for RAS. This article reviews the main approach to the action and biosynthesis of AngII: including AngII receptor blocker (ARB), chymase inhibitor and ACE2 which were disscoverd recently.
5.Effect of hypoxia preconditioning on the biological activity of rat bone marrow derived endothelial progenitor cells.
Yi LI ; Yaling HAN ; Jian KANG
Chinese Journal of Practical Internal Medicine 2001;0(02):-
Objective The aim of this investigation is to explore the effects of hypoxia on the biological activity of endothelial progenitor cells(EPC)and to improve the efficacy of EPC transplantation.Methods Rat bone marrow derived EPC were isolated and cultured either under normoxic or hypoxic conditions.The proliferation,migration and angiogenic ability of EPC were observed.Results In hypoxic group,the number of attached cells per high power field(hpf)was significantly more than that in normoxic group (91.0?8.0)vs(42.5?5.3),P
6.A Clinic Analysis of 156 Cases of Secondary Barrenness Resulted from Drug Miscarriage before Childbearing
Xiangming XU ; Shimei KANG ; Yi ZHANG
Journal of Chinese Physician 2001;0(10):-
Objective To explore the main reason of secondary barrenness resulted from drug miscarriage before childbearing. Methods Gynecologic examination was performed in 156 patients with secondary barrenness after drug miscarriage. Uterus neck and vaginal smear examination, mycoplasma and chlamydozoon detection, and hysterosalpingograghy were performed in the same time. Results 101 patients (101/156,64.74%) had genital duct inflammation,61 patients (61/156,39.1%) had various degrees of tubal obstruction. Conclusion The main reason of secondary barrenness after drug miscarriage was the tubal obstruction resulted from inflammation, especially chlamydozoon and mycoplasma infection. Drug miscarriage was not so safe before childbearing.
7.Research Advances in the Correlation of Substance P with Meridians and Acupoints
Jingqing KANG ; Yi GUO ; Kuo ZHANG
Shanghai Journal of Acupuncture and Moxibustion 2015;(4):374-376
This article reviews and summarizes recent years’ literature on the correlation of substance P with meridians and acupoints in order to provide a theoretical basis for the mechanism of acupuncture effect.
8.Treatment of the implanted VX2 liver tumor in rabbits with percutaneous intratumor AiDi injection
Yi CHEN ; Yonghuo HUANG ; Xiaobing KANG
Chinese Journal of Interventional Imaging and Therapy 2010;7(2):192-195
Objective To explore the principle,effect and method of percutaneous AiDi injection for treatment of implanted VX2 liver tumor with ultrasound guidance.Methods Twenty-eight New Zealand white rabbits with implanted VX2 liver tumors were randomly divided into 3 groups:AiDi injection group (n=12) ,percutaneous ethanol injection (PEI) group (n=8) ,and physiological saline group (n=8) .Two weeks after transplantation,the drugs were injected into tumors of all the rabbits once every 3 days.After 4 times injection,the rabbits were killed.The tumors were measured with 64-slice CT,while the rate of tumor necrosis,the volume of tumor and the growth rate of the tumor were calculated.Liver and kidney function tests (AST,ALT,ALP and BUN) as well as white blood eell counts were assessed before and after treatment,and CT examination was performed at the same time.The morphological and the ultramicrostructural changes were also investigated under light microscope or electron microscope.Results Tumors in all groups kept growing after the procedure.Among all 3 groups,tumor growing rate for AiDi injection group was the lowest and the necrotic rate was the highest (P<0.05) ,while no significant difference was found between AiDi injection group and PEI group (P>0.05) .Apoptotic index in AiDi injection group was significantly higher than that in PEI group and physiological saline group (P<0.05) .There was no evident change of liver and kidney function before and after treatment in AiDi injection group and PEI group (P>0.05) .Conclusion AiDi injection can induce apoptosis of liver VX2 tumor cells.Percutaneous AiDi injection therapy can obviously inhibit and destroy liver VX2 tumor cells.