Marjolin’s ulcer is a rare and often overlooked diagnosis
which can be encountered by a variety of specialities.
Majority of the literatures describe long latency period of 11
to 75 years. The authors present two unusual cases of rapid
progression to Marjolin’s ulcer in patients with previously
negative biopsy 8- and 10-month prior. This highlights the
importance for clinicians to have a high degree of suspicion
when encountered with any non-healing wound, especially
one who’s symptomatology and morphological features have
undergone an acute change. Even with previous negative
biopsy, patients should still be followed-up closely and
clinicians should not hesitate to perform re-biopsy if the
suspicion arises.