1.Observation of the clinical effect of acupuncture combined with speech rehabilitation training in the treatment of dysarthria after stroke
Chinese Journal of Primary Medicine and Pharmacy 2017;24(4):559-562
Objective To analyze the clinical effect of acupuncture combined with speech rehabilitation training in the treatment of dysarthria after stroke.Methods 88 patients with dysarthria after stroke were selected as study subjects,and they were randomly divided into the control group and the treatment group,44 cases in each group. The control group was treated with speech rehabilitation training,and the treatment group was treated with acupuncture combined with speech rehabilitation training.At the end of treatment,the dysarthria efficacy,a number of aand the incidence of adverse reactions were observed and compared between the two groups.Results The cure rate(9.09%) and total effective rate (77.27%)in the control group were significantly lower than those in the treatment group (25.00%,97.73%),and the differences were statistically significant(χ2 =3.94,8.42,all P <0.05).Before treat-ment,there was no significant difference between the two groups in the number of a(P >0.05),after treatment,the number of ain the control group was (7.39 ±3.67),which was significantly lower than (16.32 ±7.83)in the treatment group(t =4.20,P <0.05).The incidence rate of adverse reaction between two groups had no statistically significant difference(χ2 =3.11,P >0.05).Conclusion For post -stroke patients with dysarthria,acupuncture combined with speech rehabilitation training has good treatment effect,and the method can increase the number of aof patients,and has high security,it is worthy of widely application in clinic.
2.alphabeta T - Helper Cell Dependency in the Development of Anticardiolipin and Anti - beta2 Glycoprotein I Antibodies in MRL / MP - lpr / lpr Mice.
Korean Journal of Immunology 1997;19(3):301-306
No abstract available.
Animals
;
Antibodies*
;
Antibodies, Anticardiolipin
;
beta 2-Glycoprotein I*
;
Mice*
;
T-Lymphocytes, Helper-Inducer*
3.Fecal Bacteriotherapy for Recurrent Clostridium difficile Infection: A Systematic Literature Review.
Korean Journal of Nosocomial Infection Control 2012;17(2):70-78
BACKGROUND: Over the past several years, Clostridium difficile has become a major healthcare-associated pathogen. Fecal bacteriotherapy has been reported as an effective intervention for treating recurrent C. difficile infection by restoring the normal intestinal microbiota. METHODS: Articles on fecal bacteriotherapy were collected through PubMed, CINAHL, Cochrane Library, and Web of Science databases using the keywords "Clostridium difficile," "feces," "fecal transplantation," "fecal microbiota transplantation," and "fecal bacteriotherapy." Using a systematic literature review, variables of interest from articles that met the inclusion criteria were extracted and summarized. RESULTS: Among 141 articles that were published in English from January 1, 2000 to August 31, 2012, 8 studies were selected for analysis after assessing the titles, abstracts, and full contents. Fecal bacteriotherapy procedures varied with respect to donor selection, screening, infusion route, and preparation of the suspension. Donors were mostly family members or relatives, and donor screening included tests for blood borne and stool pathogens. Selected infusion routes were colonoscopy (62.5%), nasogastric tube (25%), and enema (12.5%). The success rate was reported to be 73-100%. There was a lack of a standard procedure for fecal bacteriotherapy in all of the selected studies. CONCLUSION: Fecal bacteriotherapy is an effective intervention for combating C. difficile infection that has a high success rate and no adverse effects. This therapy would be helpful for infection control in hospital settings by facilitating early eradication of C. difficile infection.
Clostridium
;
Clostridium difficile
;
Colonoscopy
;
Donor Selection
;
Enema
;
Feces
;
Humans
;
Infection Control
;
Mass Screening
;
Metagenome
;
Tissue Donors
4.The efficacy and mechanism of combined treatment of Reduning,budesonide and erythromycin sequential therapy in the treatment of children with mycoplasma pneumonia
Chinese Journal of Primary Medicine and Pharmacy 2012;(23):3543-3545
Objective To observe the efficacy of the combined treatment of Reduning,budesonide and erythromycin sequential therapy in the treatment of children with mycoplasma pneumonia and investigate its mechanism.Methods 78 children with mycoplasma pneumonia were randomly divided into two groups,each group 39 cases.The control group were given budesonide and erythromycin sequential therapy,and the observation group were given Reduning injection on the basis of the control group.Both groups were treated for 2 weeks.The clinical efficacy was observed,and before and after treatment,the pulmonary function was tested in the both groups.Results The total effective rate of the observation group was 94.87%,which was higher than that of the control group(86.62%)(x2=6.683,P<0.05);The fever,cough improved,pulmonary rales disappeared,wheeze disappeared and hospital stay time of the observation group were significantly shorter than the control group(all P<0.01);The FVC,FEV1 and PEF of the observation group were higher than those of the control group(all P<0.05).Conclusion On the basis of the combined treatment of budesonide and erythromycin,the addition of Reduning injection can improve clinical effect and shorten the symptoms and signs improve time,improve lung function,chich may in association with regulating humoral immunity and reducing the levels of inflammatory cytokines.
5.Development and application of HIV testing technologies for HIV/AIDS highly active anti-retroviral therapy in China
Chinese Journal of Laboratory Medicine 2009;32(4):365-368
Currently the highly active anti-retroviral therapy (HAART) is the most effective and practical approach for AIDS treatment. However, as the public health strategy for HIV/AIDS prevention and control, governmental involvement is highly needed. Since 2004 Chinese govemment actively responded to the United Nations' proposition and promised, "Four Free and One Care" policy, to promote HAART for AIDS patients in whole country, which was free of charge for all the AIDS patients. HIV related testing technologies are important assurance for effective implementation of HAART and replacement of anti-HIV drugs, including screening and confirmation of HIV/AIDS patients, screening of patients for HAART, evaluation of treatment effcacy and side effects, monitoring HIV-1 drug resistance and molecular evolution. In this issue, there are 6 papers describing the research on HAABT and relevant HIV testing technologies. The studies clearly demonstrated that great development was made in HIV testing technologies, which played significant supportive roles for HAART implementation in China.
6.Is It Essential to Consider Respiratory Dynamics?.
Korean Journal of Critical Care Medicine 2017;32(2):223-224
No abstract available.
Positive-Pressure Respiration, Intrinsic
;
Airway Resistance
;
Bronchitis, Chronic
;
Lung Compliance
;
Vena Cava, Inferior
;
Work of Breathing
;
Heart Ventricles
;
Blood Pressure
;
Pulmonary Disease, Chronic Obstructive
;
Lung
;
Respiratory Muscles
;
Pulmonary Emphysema
;
Emphysema
;
Pneumonia
;
Cardiac Output
;
Lung Transplantation
;
Intensive Care Units
;
Positive-Pressure Respiration
;
Barotrauma
;
Hypotension
;
Korea
7.Effect of dexmedetomidine on stress response and inflammatory reaction of patients with hysterectomy
Chinese Journal of Biochemical Pharmaceutics 2017;37(4):339-342
Objective To study the effect of dexmedetomidine on stress response and inflammatory reaction of patients with hysterectomy.Methods 96 patients with hysterectomy who received therapy from October 2014 to October 2016 in Jinhua traditional Chinese medicine hospital were selected.According to random number table,those patients were divided into the observation group(n=48)and the control group(n=48).Two groups were treated with total intravenous anesthesia,the observation group was treated with intravenous infusion of dexmedetomidine1μg·kg-1 before anesthesia,pump is completed within 15 minutes,then continuous injection of 0.5μg·kg-1·h-1 speed to the 30min before the end of the operation; the control group was given the same way of infusion of normal saline.The operation time,blood loss,recovery time,extubation time and length of stay were recorded,and the hanges of mean arterial pressure(MAP),heart rate(HR),hydrogen peroxide(H2O2),malondialdehyde(MDA),total antioxidant status(TAS),tumor necrosis factor(TNF)-α,interferon(IFN)-γ,interleukin(IL)-10 at T0(before anesthesia),T1(at the end of pneumoperitoneum),T2(after the end of pneumoperitoneum 30min),T3(postoperative 24h)were recorded.Results There was no significant difference between the two groups in operation time,blood loss,recovery time,extubation time and length of stay; in the control group,the MAP was significantly reduce at T1,T2 was significantly higher,the HR was significantly reduce at T1(P<0.05); there was no significant change of MAP and HR levels in the observation group at each time point; the H2O2 and MDA in the observation group were lower than that of the control group at T1,T2 and T3,and the TAS was higher than that of the control group(P<0.05); the TNF-α,IFN-γ and IL-10 in the observation group were lower than that of the control group at T1,T2 and T3(P<0.05).Conclusion Intravenous infusion of dexmedetomidine before anesthesia is well for patients with hysterectomy,it'is helpful to maintain the hemodynamic stability,and effectively alleviate the stress response,inflammation reaction,it's worth promoting.
8.Efficacy of percutaneous kyphoplasty for osteoporosis vertebral compression fractures
International Journal of Surgery 2016;43(5):325-328
Objective To conclude the technology and clinical outcomes of percutaneous kyphoplasty for the treatment of osteoporotic vertebral compression fractures.Methods From June 2011 to June 2014,29 cases of osteoporoticthoracic and lumbar vertebral compression fractures patients,who were diagnosed by ultrasonic bone mineral density measurement.X-ray,CT and MRI were treated with percutaneous kyphoplasty in Beijing 401 Hospital of China Nuclear Industry.Observed and recorded the degree of pain,patient's activity and the recovery of vertebral height in patients with 24 hours,3 months and 6 months after operation.The index data were analyzed by SPSS 17.0 statistical software,and the measurement data were analyzed by paired t test.Results Twenty-nine patients were operated successfully,17 cases (58.62%)of back pain disappeared and 12 cases (41.38%) of back pain significantly reduced.Twenty-seven cases (93.1%) were allowed to get off bed after 24 hours of operation and 2 cases (6.9%) after 3 days.Three cases (10.34%) occurred PMMA leakage.After 24 hours,3 months and 6 months VAS and vertebral height of the original vertebral height percentages are much better than before surgery (P <0.01),after 3 months and 6 months VAS scores were significantly better than surgery after 24 hours (P < 0.01),and with the extension of the observation,VAS scores decreased,but the degree of decline in after three months and six months was no statistical significance (P > 0.05).Compared after surgery 3-month and 6-month with after surgery 24 hours,the vertebral height have lost,but the lost height of the vertebral was no statistical significance (P > 0.05).No infection,hematoma,spinal nerve injury and PMMA poisoning complications occurred.Conclusions Percutaneous kyphoplasty can relieve the pain and restore part of the vertebral height satisfactory with better outcomes.
9.Observation on clinical effects of tuina plus montelukast sodium tablets for children with cough variant asthma
Journal of Acupuncture and Tuina Science 2017;15(5):349-353
Objective:To observe the clinical effects of tuina plus oral administration of montelukast sodium tablets for children with cough variant asthma (CVA). Methods:A hundred and six children with CVA were randomly divided into a treatment group and a control group, 53 cases in each group. The treatment group was treated with Tuina therapy plus oral administration of montelukast sodium tablets, and the control group was treated only by oral administration of montelukast sodium tablets. Tuina treatment was given three times per week. 5 mg of montelukast sodium tablets was given orally before bedtime every night. The therapeutic effects were assessed after the treatment of four weeks in both groups. Results:The total effective rates were 92.5% in the treatment group and 77.4% in the control group. The difference in the total effective rate between the two groups was statistically significant (P<0.05). Conclusion:The therapeutic effect of tuina plus montelukast sodium tablets for children with CVA is better than that of oral administration of montelukast sodium tablets alone.
10.Outcomes of percutaneous coronary intervention combined with edaravone injection in treating ST-segment elevation acute myocardial infarction
The Journal of Practical Medicine 2014;(11):1729-1731
Objective To observe the efficacy and clinical security of percutaneous coronary intervention combined with edaravone injection in treating ST-segment elevation acute myocardial infarction. Methods Group A was treated with conventional percutaneous coronary intervention plus edaravone injection , while group B was treated only with conventional percutaneous coronary intervention. Outcomes were compared between these two groups after the intervention. Results The two groups were successfully operated by percutaneous coronary intervention treatment. Thrombolysis in myocardial infarction,TIMI myocardial perfusion grade and ST-segment recovery after operation had no significant difference. After 48 h treatment, MDA in serum of group A was (3.16 ± 0.12)mol/L. Serum MDA content in group B, was (4.38 ± 0.13)mol/L. The difference was statistically significant (P<0.05). In addition, 7 d cardiac function indexes and cardiac arrhythmia rate were lower than those in group B (P < 0.05). Conclusions The combination use of percutaneous coronary intervention and edaravone can effectively improve heart function in patients shortly in the treatment of ST-segment elevation acute myocardial infarction.Hhowever, the further studies are still needed to evaluate the long term efficacy.