Objective To analyze the clinical effect of acupuncture combined with speech rehabilitation training in the treatment of dysarthria after stroke.Methods 88 patients with dysarthria after stroke were selected as study subjects,and they were randomly divided into the control group and the treatment group,44 cases in each group. The control group was treated with speech rehabilitation training,and the treatment group was treated with acupuncture combined with speech rehabilitation training.At the end of treatment,the dysarthria efficacy,a number of aand the incidence of adverse reactions were observed and compared between the two groups.Results The cure rate(9.09%) and total effective rate (77.27%)in the control group were significantly lower than those in the treatment group (25.00%,97.73%),and the differences were statistically significant(χ2 =3.94,8.42,all P <0.05).Before treat-ment,there was no significant difference between the two groups in the number of a(P >0.05),after treatment,the number of ain the control group was (7.39 ±3.67),which was significantly lower than (16.32 ±7.83)in the treatment group(t =4.20,P <0.05).The incidence rate of adverse reaction between two groups had no statistically significant difference(χ2 =3.11,P >0.05).Conclusion For post -stroke patients with dysarthria,acupuncture combined with speech rehabilitation training has good treatment effect,and the method can increase the number of aof patients,and has high security,it is worthy of widely application in clinic.

No abstract available.
Animals ; Antibodies* ; Antibodies, Anticardiolipin ; beta 2-Glycoprotein I* ; Mice* ; T-Lymphocytes, Helper-Inducer*

Currently the highly active anti-retroviral therapy (HAART) is the most effective and practical approach for AIDS treatment. However, as the public health strategy for HIV/AIDS prevention and control, governmental involvement is highly needed. Since 2004 Chinese govemment actively responded to the United Nations' proposition and promised, "Four Free and One Care" policy, to promote HAART for AIDS patients in whole country, which was free of charge for all the AIDS patients. HIV related testing technologies are important assurance for effective implementation of HAART and replacement of anti-HIV drugs, including screening and confirmation of HIV/AIDS patients, screening of patients for HAART, evaluation of treatment effcacy and side effects, monitoring HIV-1 drug resistance and molecular evolution. In this issue, there are 6 papers describing the research on HAABT and relevant HIV testing technologies. The studies clearly demonstrated that great development was made in HIV testing technologies, which played significant supportive roles for HAART implementation in China.

The activation of CD40-CD40L costimulatory signal channel plays a necessary role in T cellmediated immune response. Activation of CD40 on antigen presenting cells by CD40L which expressed on Tlymphocytes, while contributing to the pro-in? ammatory response necessary for eradication of infection, accounts for the pathology in autoimmunity. Meanwhile, there is evidence that CD40 is also expressed on T-lymphocytes and can act as a costimulatory molecule. Further dissection of the exact nature and role of CD40 in T cell activation could lead the way to novel therapeutics for diseases which include organ-graft refection, autoimmune diseases,tumor, and inflammation.

Sepsis has become a widespread and very complex issue for modern critical care medicine.It is undoubtedly of great theoretical and clinical significance that we should strengthen the study of sepsis and explore new treatments and drugs.It has been found that curcumin had anti-tumor,anti-inflammatory,anti-virus,antibacterial,antioxidant and other pharmacological effects,low toxicity,and a good potential for clinical application.Moreover,it was thought to be potentially immunomodulatory in the last two decades.A number of experimental studies had elicited that curcumin could be used for sepsis and septic shock.This article reviews the immune regulation mechanism of curcumin in sepsis.

After the challenges facing reading therapy and the methods to provide reading therapy service in academic libraries were described , the steps and measures to provide reading therapy service using mobile telephone were pointed out.

Congenital nephrotic syndrome,the common cause of end stage renal disease in chidren,is a rare kidney disorder.With the advanced molecular biology,much progress have been made in its etiology,diagnosis and treatment.This paper will mainly focus on its classification,diagnosis and therapy.

Patent ductus arteriosus is a common congenital heart disease in children.Effective and promptly treatment can prevent complications,such as pneumonia,congestive heart failure,infective endocarditic and pulmonary artery hypertension.The treatments include medication,transcatheter intervention and surgery.The vast majority of the patent ductus arteriosus can be cured by transcatheter interventional therapy now.

Objective To observe the efficacy of the combined treatment of Reduning,budesonide and erythromycin sequential therapy in the treatment of children with mycoplasma pneumonia and investigate its mechanism.Methods 78 children with mycoplasma pneumonia were randomly divided into two groups,each group 39 cases.The control group were given budesonide and erythromycin sequential therapy,and the observation group were given Reduning injection on the basis of the control group.Both groups were treated for 2 weeks.The clinical efficacy was observed,and before and after treatment,the pulmonary function was tested in the both groups.Results The total effective rate of the observation group was 94.87％,which was higher than that of the control group(86.62％)(x2=6.683,P＜0.05);The fever,cough improved,pulmonary rales disappeared,wheeze disappeared and hospital stay time of the observation group were significantly shorter than the control group(all P＜0.01);The FVC,FEV1 and PEF of the observation group were higher than those of the control group(all P＜0.05).Conclusion On the basis of the combined treatment of budesonide and erythromycin,the addition of Reduning injection can improve clinical effect and shorten the symptoms and signs improve time,improve lung function,chich may in association with regulating humoral immunity and reducing the levels of inflammatory cytokines.

Objective According to the analyses of adverse drug reactions (ADR) in clinic, we supply reasonable drug information for clinical usage to reduce recurrence of adverse reactions. Methods Analyze the ADR reports of our hospital from April, 2007 to December, 2008 and make statistical analysis by terms of age of patients, kinds of drugs, route of administration, clinical manifestation, and recovery, etc. Result The incidence rate of ADR in the female is more than the male. ADR mainly involves with the skin, nervous system, respiratory system, and digestive system. Clinical manifestations mainly show as rash, local swelling, erythema, irritations, dizziness, headache, fever, sweating, shiver, chest tightness, short breath, heart palpitation, dyspnea, sickness, vomiting, abdominal pain and distension etc. Conclusion Antibiotics should be reasonably used; Traditional Chinese medicinal injection should be used according to syndrome differentiation and be avoided used with the combination with other medicines. Dosage and injecting speed should also be strictly controlled to reduce and avoid ADR happening again.