1.Progress of lymphadenectomy by video-assisted thoracic surgery for early stage non small cell carcinoma
Kaiying XU ; Sihua WANG ; Jianjun WANG
Journal of Clinical Surgery 2017;25(7):556-558
Lung cancer is the most important cause for cancer death globally,and it ranks the first position in morbidity and mortality among all malignances in China.non small cell lung cancer(NSCLC)accounts for approximately 80% of all lung cancinoma.Surgical resection is the major treatment method for early stage NSCLC.Video-assisted thoracic surgery(VATS) is becoming the preferred surgical procedure for early stage NSCLC,because of it's minimally invasive features.However,controversy remains regarding the extent of lymph node dissection and the completeness of the lymphnode dissection by VATS for early stage NSCLC.This article is a brief review concerning this two questions.
2.Progress of endoscopic interventional treatment for postoperative bronchopleural fistula in lung cancer
Journal of Clinical Surgery 2018;26(3):231-233
Postoperative bronchopulmonary fistula(BPF) in lung cancer is an abnormal pathway formed by the bronchus communicating with the pleural cavity after pneumonectomy. Although surgical techniques and perioperative management have been improved, BPF is still a therapeutic challenges to thoracic surgeons. The treatment methods mainly include conservative treatment, surgical treatment and endoscopic interventional therapy. Among them, endoscopic interventional therapy is more and more widely used due to its minimally invasive characteristics, and has achieved a good therapeutic effect. This article reviews the endoscopic interventional treatment of BPF after pneumonectomy and hopes to provide some assistance for treatment of BPF.
3.Clinical Efficacy of Liuwei Dihuangwan Combined with Aclasta on Osteoporosis and Effect on Quality of Life
Xu YANG ; Huaxin WANG ; Qian ZHANG ; Guoqiang ZHANG ; Kaiying CUI ; Guoyan LIU
Chinese Journal of Experimental Traditional Medical Formulae 2022;28(14):115-120
ObjectiveTo study the efficacy of Aclasta combined with Liuwei Dihuangwan on osteoporosis and the effect on quality of life. MethodA total of 126 patients with osteoporosis who were treated in the Affiliated Hospital of Shandong University of Traditional Chinese Medicine from September 2019 to September 2020 were classified into the observation group and the control group with the randomized double-blind method. The observation group consisted of 60 patients (26 males and 34 females) with the age of 59-85 years old [mean: (72.0 ± 6.5) years old]. The control group was composed of 66 patients (31 males and 35 females), with the age of 62-82 years old [mean: (73.0±8.2) years old]. The control group was treated with Aclasta, and the observation group Aclasta combined with Liuwei Dihuangwan. After treatment, the effective rate of each group was calculated. Bone mineral density (BMD) was measured in both groups before and after treatment, and serological parameters calcium (Ca), total 25 (OH) vitamin D3 (VITD-T), osteocalcin (OC), serum alkaline phosphatase (ALP), parathyroid hormone (PTH), β-collagen special sequence (β-CTX), and total procollagen 1 N-terminal propeptide (T-P1NP) were also measured. Visual Analogue Scale (VAS) score, Japanese Orthopaedic Association (JOA) score, and Oswestry Disability Index (ODI) score were evaluated. On this basis, the effect was compared between the two groups. ResultThe indexes were insignificantly different between the two groups before treatment. After 6 months of treatment, the two groups showed decrease in VAS score and ODI score (P<0.01), increase in JOA score (P<0.01), BMD of lumbar spine and hip joint, elevation of Ca, VITD-T, OC, ALP, and PTH (P<0.05, P<0.01), and decrease of β-CTX (P<0.01) as compared with before treatment. The level of T-P1NP dropped in the observation group after treatment (P<0.01).After treatment, the total effective rate of the observation group was 88.3% (53/60), as compared with the 74.2% (49/66) in the control group (χ2=4.047, P<0.05). Moreover, after treatment, the observation group demonstrated higher levels of BMD, Ca, VITD-T, OC, and PTH (P<0.05), lower levels of T-P1NP (P<0.05), lower VAS score (P<0.01), and higher JOA score (P<0.05) than the control group, but the ODI score was insignificantly different from that in the control group. ConclusionAclasta combined with Liuwei Dihuangwan is effective on osteoporosis, without increasing the incidence of adverse reactions. In addition, the combination can alleviate pain and improve the quality of life of osteoporosis patients.
4.Short-term outcomes and learning curve of the robot-assisted Heller-Dor myotomy for achalasia of cardia: A single-center retrospective study
Chunlin YE ; Guangxia WEI ; Kaiying XU ; Lei JIANG ; Bin XU ; Quanjin LI ; Zhi HU ; Bentong YU ; Jian TANG
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery 2022;29(04):443-448
Objective To investigate short-term outcomes of robot-assisted Heller-Dor myotomy (RAHM-Dor) for achalasia of cardia and our learning curve experience. Methods The clinical data and recent follow-up results of 42 patients who received RAHM-Dor from November 2015 to January 2020 in the Department of Thoracic Surgery of the First Affiliated Hospital of Nanchang University were retrospectively analyzed, including 20 males and 22 females with a mean age of 40.8±18.4 years. Results Dysphagia was the most common symptom, followed by heartburn and regurgitation. The mean operation time was 122.8±23.9 min. The mean blood loss was 47.5±32.7 mL. Two patients suffered mucosal injury, and successfully repaired by suturing during surgery. There was no esophageal fistula, conversion to an open operation or perioperative death in this series. The median length of hospital stay was 8 (6, 9) d. In all patients, the Stooler and Eckardt scores of postoperative 1, 6 and 12 months decreased compared to those of pre-operation (P<0.001). Conclusion RAHM-Dor is a safe and feasible avenue for the treatment of achalasia of cardia, and can achieve a satisfying short-term results. The learning curve shows a transition to the standard stage from the learning stage after 16-18 operations.
5.Surgical treatment of latent infection of 2019 novel coronavirus (SARS-CoV-2) with esophageal foreign body perforation: A case report
TONG Song ; CHEN Zhuo ; WU Chuangyan ; XU Kaiying ; YANG Guanghai ; LIAO Yongde ; WANG Sihua
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery 2020;27(03):240-242
This study reports the surgical treatment of a female patient at age of 64 years with novel coronavirus (SARS-CoV-2) latent infection complicated with esophageal foreign body perforation with no significant changes in the lung CT. The patient was confirmed as SARS-CoV-2 infection on the 4th day after surgery and then was transferred into the Department of Infectious Disease in our hospital for treatment. This case has guiding value for the operation of thoracic surgery during the outbreak of novel coronavirus pneumonia.