1.Evaluation of quality of life in patients with advanced laryngeal cancer
Zining ZHOU ; Guowei JIN ; Wei WEI ; Jihong SHI ; Kaixu XU ; Shaocheng LI
Chinese Archives of Otolaryngology-Head and Neck Surgery 2006;0(03):-
OBJECTIVE To find the differences in QOL between patients treated with total laryngectomy with voice rehabilitation or without voice rehabilitation and subtotal laryngectomy, to analysis the factors affecting QOL of patients after laryngectomy by HNQOL. METHODS With HNQOL,a survey was conducted in patients treated with total laryngectomy (30cases) with voice rehabilitation, 30 cases without voice rehabilitation, and 30 cases treated with subtotal laryngectomy for laryngeal cancer. We discuss changes of QOL with time went by,and analysis the factors affecting QOL of patients after laryngectomy. RESULTS There is no difference between patients treated with total laryngectomy with .voice rehabilitation and the one treated with subtotal laryngectomy in their quality of life, however, there is difference between patients treated with total laryngectomy without voice rehabilitation and the one treated with subtotal laryngectomy. CONCLUSION Through voice rehabilitation ,we could advance quality of life of the patients treated with total laryngectomy. Through the integration of psychological, clinical and social intervention, the quality of life of patients may have an overall improvement.
2.Feature of semicircular canal function in obstructive sleep apnea-hypopnea syndrome.
Xi HAN ; Honghua LU ; Email: LUHONGHUA10@SINA.COM. ; Taisheng CHEN ; Kaixu XU ; Peng LIN ; Email: LINPENGF@SINA.COM. ; Chao WEN ; Qianwei LI ; Yan CHENG ; Wei WANG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2015;50(6):482-487
OBJECTIVEThe aim of this study was to evaluate the effects of obstructive sleep apnea-hypopnea syndrome (OSAHS) on semicircular canal function.
METHODSBy means of a series prospective study at Department of Otolaryngology Head and Neck Surgery of our hospital, the study was performed on 77 patients suffering from OSAHS in a period from 2012 to 2014, who underwent polysomnography (PSG) and caloric test. The maximal slow-phase velocity (SPV) and unilateral weakness (UW) were used to measure the vestibular function. Severity of OSAHS was evaluated by the lowest oxygen saturation (LSaO₂) and apnea hypopnea index (AHI). The SPV after cool was signed, warm test was performed for each ear, and the sum of left ear SPV were calculated, and then, the SPV of right ear was counted as the same way. Finally, the relationships between LSaO₂, AHI, age, BMI, and SPV of caloric test were analyzed.
RESULTSCaloric vestibular tests in the 77 OSAHS patients demonstrated abnormal findings in 52 patients (67.5%) and normal vestibular functions in the remaining 25 patients (32.5%). Of the 52 patients with an abnormal test result, 16 (20.8%) patients had unilateral vestibular hyporeflexia and 36 (46.7%) patients revealed a bilateral vestibular hyporeflexia. There was no linear relationship between AHI, age, BMI with SPV of caloric test (P > 0.05). The SPV had significant difference between Lower LSaO₂group (LSaO₂< 50%) and higher LSaO₂group (LSaO₂≥ 80%) (P < 0.05). LSaO₂was lower in patients undertaken bilateral vestibular hyporeflexia.
CONCLUSIONSOSAHS patients with long-term intermittent hypoxia can disturb the vestibular organs and reduce semicircular canal function. The heavier hypoxemia will lead to the lower reflex of semicircular canal, with the heavier degree of hypoxemia, and the bilateral horizontal semicircular canal involvement may also be higher at the same time. Due to the effect of vestibule centre compensatory, OSAHS patients lack of dizziness and symptoms from balance disturbances such as typically acute vestibular damage.
Caloric Tests ; Humans ; Hypoxia ; complications ; Polysomnography ; Prospective Studies ; Semicircular Canals ; physiopathology ; Sleep Apnea, Obstructive ; diagnosis ; physiopathology ; Vertigo ; complications
3.Evaluation of the injured range of vestibular superior and inferior nerves in sudden deafness patients with vertigo using video head impulse test.
Lingxiao HOU ; Taisheng CHEN ; Kaixu XU ; Wei WANG ; Shanshan LI ; Qiang LIU ; Chao WEN ; Yan CHENG ; Hui ZHAO ; Yuanxu MA ; Peng LIN ; Email: LINPENGF@SINA.COM.
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2015;50(9):718-723
OBJECTIVETo discuss the video head impulse tests (vHIT) application values in assessment of the vestibular nerves, function in sudden deafness patients with vertigo.
METHODSThere were 60 cases (120 ears) of healthy volunteers as control group, and 182 cases (182 ears) of sudden deafness with vertigo patients as study group. The study group received vHIT and caloric test, and the control group received vHIT. Functions of vestibular superior and inferior nerves were analyzed by the gains of vHIT and the nystagmus, s unilateral weakness of caloric test, with SPSS17.0 software.
RESULTSThe values of vHIT-G of the six semicircular canals in the control group were normal distribution and no statistical significance among them (F = 0.005, P = 1.000). The vHIT-G averages of both sides of anterior, horizontal and posterior semicircular canals were (15.20 ± 11.00) %, (15.30 ± 13.30) %, and (15.15 ± 14.72) % respectively. In the study group, the vHIT-G of the affected side were (21.73 ± 14.84) %, (21.20 ± 28.24) %, and (19.22 ± 23.50) %, with normal distribution, and in which statistical significance was detected comparing with those in the control group (P < 0.05). The positive rates were 26.9% (49/182) in vHIT, 70.3% (128/182) in caloric test. Significant difference (P < 0.05) was observed between vHIT and caloric test examined by chi-square test. According to the results of vHIT, there were 15 cases (8.2%) damaged vestibular superior and inferior nerves areas, 19 cases (10.4%) damaged the superior vestibular nerve area, and 15 cases (8.2%) damaged the inferior vestibular nerve area. In combination with caloric test results, it was shown that there were 29 cases (15.9%) damaged vestibular superior and inferior nerves areas, 101 cases (55.5%) damaged the superior vestibular nerve area, and 1 case (0.5%) damaged the inferior vestibular nerve area.
CONCLUSIONSvHIT can assess the function of six semicircular canals and illustrate high frequency of vestibular nerves. Caloric test combined with vHIT have more advantages to comprehensive assess vestibular damage of sudden deafness patients with vertigo.
Caloric Tests ; Case-Control Studies ; Head Impulse Test ; Hearing Loss, Sudden ; diagnosis ; Humans ; Nystagmus, Pathologic ; physiopathology ; Semicircular Canals ; pathology ; Vertigo ; diagnosis ; Vestibular Nerve ; pathology ; Vestibule, Labyrinth ; pathology
4.Clinical values of the sensory organization test in vestibular diseases.
Ming HU ; Taisheng CHEN ; Email: CTS501@SOHU.COM. ; Hong DONG ; Wei WANG ; Kaixu XU ; Peng LIN
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2015;50(9):712-717
OBJECTIVETo explore the clinical values of Sensory Organization Test (SOT) of dynamic posturography in the diagnosis of peripheral vertigo.
METHODSA total of 112 patients with peripheral vertigo were retrospectively analyzed. All the patients firstly underwent the inspection of SOT followed by caloric test. The results were conducted a comparative analysis. Assessments of SOT evaluated the patient's effective use of visual, vestibular, and somatosensory information for balance control during a variety of changing task conditions. The unilateral weakness was selected as assessment parameter of caloric test. Fourty-two healthy subjects were selected as control group underwent the dynamic posturography.
RESULTSAmong the 42 cases of control group, results of SOT in dynamic posturography were normal. The SOT composite scores owned a significant difference between control and peripheral vertigo subjects. Among the 112 cases with peripheral vertigo, results of SOT in dynamic posturography were abnormal in 37 cases, with a sensitivity of 33.0%; caloric test was abnormal in 72 cases, with a sensitivity of 64.3%. There existed a significant difference between dynamic posturography and caloric test.
CONCLUSIONSOT is a key test in dynamic posturography that reflects the balance reconstruction after peripheral injury, and provides information about the integration and proportion of the visual, proprioceptive, and vestibular components of balance.
Caloric Tests ; Case-Control Studies ; Humans ; Postural Balance ; Retrospective Studies ; Sensitivity and Specificity ; Vertigo ; diagnosis ; Vestibular Diseases ; diagnosis ; Vestibule, Labyrinth ; physiopathology
5.The application of subjective visual gravity in assessment of vestibular compensation: a pilot study.
Yuan ZHAO ; Taisheng CHEN ; Wei WANG ; Kaixu XU ; Chao WEN ; Qiang LIU ; Xi HAN ; Shanshan LI ; Xiaojie LI ; Peng LIN
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2016;51(5):355-360
OBJECTIVETo discuss the characteristics of subjective visual gravity (subjective visual vertical/horizontal, SVV/SVH) and assess its clinical application for peripheral unilateral vestibular compensation.
METHODS69 cases of acute peripheral unilateral vestibular dysfunction patients (case group) accepted SVV/SVH, spontaneous nystagmus (SN), caloric test (CT) and other vestibular function tests. 49 healthy people (control group) accepted SVV/SVH only. SVV/SVH, SN and unilateral weakness (UW) were selected as for the observation indicators. The correlations between SVV/SVH, SN, UW and courses were investigated respectively, as well as the characteristic of SVV/SVH, SN in period of vestibular compensation.
RESULTSAmong case group SVV, SVH positive in 42 patients(60.9%) and 44 patients(63.8%), the absolute values of the skew angle were in the range between 2.1°-20.0°, 2.1°-22.2°. Skew angles of SVV/SVH in control were in the range between -1.5°-2.0° and -2.0°-1.6°, and had no statistical significance with case group(t=5.336 and 5.864, P<0.05). SN-positive 28 cases (40.6%), the range of intensities at 2.4°-17.1°; UW-positive 50 cases (72.5%). In case group, positive correlation between SVV and SVH(r=0.948, P=0.00), negatively correlated between SVV/SVH and SN respectively(r values were -0.720, -0.733, P values were 0.00), no correlation between the skew angle of SVV/SVH, strength of SN and UW value(r values were 0.191, 0.189, and 0.179, P>0.05), there was no correlation between the absolute value of SVV, SVH, SN, UW with the duration (rs values were -0.075, -0.065, -0.212, and 0.126, P>0.05).
CONCLUSIONSubjective visual gravity can be used not only to assess the range of unilateral peripheral vestibular dysfunction, but also help assess the static compensatory of otolithic, guidance and assessment of vestibular rehabilitation.
Caloric Tests ; Gravitation ; Humans ; Otolithic Membrane ; Pilot Projects ; Vestibular Diseases ; physiopathology ; Vestibular Function Tests ; Vestibule, Labyrinth ; physiopathology ; Visual Perception
6. A pilot study of the unilateral centrifugation subjective visual vertical in healthy young people
Taisheng CHEN ; Xi HAN ; Qiang LIU ; Shanshan LI ; Chao WEN ; Wei WANG ; Kaixu XU ; Peng LIN
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2018;53(11):811-814
Objective:
To evaluate the data of unilateral centrifugation subjective visual vertical (UC-SVV) in healthy young people.To study the function of utricle.
Methods:
Between Decem ber 2017 and May 2018, thirty-two healthy young volunteers were tested by static subjective visual vertical(SVV) and low velocity UC-SVV with Neuro Kinetics Inc I-portal 6.0 Video nystagmus recording system and NOTC rotating chair system.The static SVV preset angle were -15.00°, 15.00°, -20.00°, 20.00°, -12.00° and 12.00° respectively.UC-SVV test parameters: rotating chair′s peak speed was 60°/s.The shift time from the middle to the lateral position was 30 s and the displacement was 3.85 cm.The chair rotated at 60 s at left, right and middle positions.Subjects underwent SVV during this period.SPSS 17.0 software was used to analyze the data.
Results:
The mean and standard deviation of static SVV deviation in 32 volunteers was 0.21°±0.17°, 95%
7. The nystagmus characteristics of two positions of the horizontal semicircular canal cupulolithiasis
Chao WEN ; Wei WANG ; Kaixu XU ; Qiang LIU ; Shanshan LI ; Xi HAN ; Taisheng CHEN ; Peng LIN
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2018;53(12):888-892
Objective:
To analyze the characteristics of nystagmus of horizontal semicircular canal cupulolithiasis(HSC-Cup) in Roll test and Dix-Hallpike test.
Methods:
Between December 2016 and December 2017, a total of 164 patients with BPPV from Tianjin First Center Hospital, 124 HSC-Can BPPV and 40 HSC-Cup BPPV, were involved.The induced nystagmus in Roll test and Dix-Hallpike test were recorded by video-nystagmograph(VNG), whose direction and intensity characteristics were compared in various BPPV.
Results:
HSC-Can patients were induced a horizontal nystagmus with Roll test, the nystagmus intensity of the disease and healthy side were (41.3±20.1)°/s (mean standard deviation)and(21.9±9.4)°/s respectively, the difference was statistically significant (
8. The characteristics and clinical significance of vestibular autorotation test in patients with vestibular migraine
Wei WANG ; Thungavelu YOGUN ; Taisheng CHEN ; Shanshan LI ; Peng LIN ; Kaixu XU ; Qiang LIU ; Chao WEN
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2018;53(12):909-913
Objective:
To investigate the characteristics and clinical utility of vestibular autorotation test (VAT) in patients with vestibular migraine(VM).
Methods:
This study included two groups, a VM group (441 patients from Tianjin First Center Hospital between January 2015 and May 2016) and a control group (65 healthy subjects). Both groups undertook VAT; the parameters evaluated were horizontal gain/phase, vertical gain/phase and asymmetry. The differences in VAT results between the two groups were investigated.
Results:
There were statistically significant differences in VAT results between the VM and the control group, namely elevated horizontal gain at frequency 2, 3, 4 and 5 Hz, delay horizontal phase at frequency 2, 4, 5 and 6 Hz, elevated vertical gain at frequency 2-6 Hz and delay vertical phase at frequency 4-6 Hz. There was no significant difference in asymmetric values between the VM group and the control group.
Conclusions
The results of this study indicate that VM patients have elevated horizontal gain and vertical gain, and delay horizontal phase and vertical phase. It is suggested that VAT represents a useful diagnostic tool which may provide objective evidence for the diagnosis and differential diagnosis of VM.
9. Frequency characteristics of the semicicular canals damage in patients with Meniere disease
Kaixu XU ; Taisheng CHEN ; Wei WANG ; Shanshan LI ; Qiang LIU ; Chao WEN ; Xi HAN ; Peng LIN
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2017;52(3):190-194
Objective:
To evaluate semicircular canal damage and its frequency characteristics in Meniere disease patients.
Methods:
Sixty-seven Meniere disease patients accepted the video-head impulse test(vHIT)which responses to semicircular canal function of high frequency area, head shaking test(HST) which responses to semicircular canal function of middle frequency area, and caloric test(CT) which responses to semicircular canal function of low frequency area.Preferences were recorded including the video head impulse test gain (vHIT-G), head shaking nystagmus (HSN) and parameters of the unilateral weakness (UW) as observation index, and results of all the three tests were analyzed according to Meniere disease patients. SPSS 17.0 software was used to analyzed the data.
Results:
The positive rate of CT, HSN and vHIT were 70.1%(47/67), 41.8%(28/67) and 23.9%(16/67) respectively. Comparation of the positive rate among CT, HST and vHIT showed statistically significant difference (χ2=10.93,
10. The exploration on optimization of two alternatives between roll test and Dix-Hallpike test in benign paroxysmal positional vertigo
Ran JI ; Taisheng CHEN ; Wei WANG ; Kaixu XU ; Shanshan LI ; Chao WEN ; Qiang LIU ; Peng LIN
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2017;52(6):440-445
Objective:
To analyze the objective characteristics of roll test and Dix-Hallpike test in benign paroxysmal positional vertigo(BPPV)patients, discussing the premier solution of positional test.
Methods:
A total of 230 patients with BPPV, whereas 170 posterior semicircular canal canalithiasis (PSC-Can) BPPV and 60 horizontal semicircular canal canalithiasis (HSC-Can) BPPV were involved respectively. The induced nystagmus in roll test and Dix-Hallpike test was recorded by video nystagmuo graph (VNG), and the direction, intensity and time characteristics of nystagmus were compared in various BPPV.SPSS19.0 software was used for statistical analysis.
Results:
Vertically upward nystagmus was induced by hanging in 170 PSC-Can Dix-Hallpike test, and the nystagmus reversed and turned weaker when the subjects came to sit. The intensity of nystagmus at turning to lesion side by hanging and sitting were (30.3±14.1)°/s and (12.6±7.5)°/s respectively, the difference was statistically significant (