AIM: To establish a method for the determination of trace amounts arsenic in Pule'an Tablet (Chinese Cabbage Pollen). METHODS: Hydride generation atomic absorption spectrometry was used to determine arsenic by microwave digesting sample. RESULTS: The detection limit of the method was 0.045 ?g/Kg, RSD= 5.9%, the recovery was in the range of 90%～106%. CONCLUSION: The method is simple,rapid and with high sensitivity, and can be applied for the determination of trace amounts arsenic in Pule'an Tablet.