1.Dislocation and replacement of practice teaching course in personnel training of medical law
Chinese Journal of Medical Education Research 2014;(1):45-48
At present stage,the needs of practice personnel of medical law include‘professional personnel’ (master's degree)and ‘general personnel’(bachelor's degree),but the existing training system did not make any distinction between the two and triggered the following situations:practical teaching mode convergence,content inanition,lack of resources,etc. From the real needs of the com-munity,practice teaching in master stage should focus on vocational practical trainingcourse including mock trial,common medical law disputes,professional documents writing. Practice teaching in un-dergraduate stageshould focus on the primary practical trainingcourse including court records and medical dispute mediation.
3.Study on tendon arthralgia syndrome and its application to diagnosis and treatment of tendon injury disease.
Yue HU ; Kai-qun SUN ; Ning KONG
China Journal of Orthopaedics and Traumatology 2014;27(8):700-705
Arthralgia
;
diagnosis
;
etiology
;
therapy
;
Humans
;
Medicine, Chinese Traditional
;
Syndrome
;
Tendon Injuries
;
diagnosis
;
therapy
4.Finite element simulation of 3D heat transfer in forearms based on anatomic structure of vessels
Qiao YU ; Kai YUE ; Xinxin ZHANG
Chinese Journal of Tissue Engineering Research 2007;0(22):-
Based on the anatomic data and fractal theory, the vascular tree model of forearms similar to actual vessel was established, and then the 3D heat transfer model of forearms based on the actual vessel anatomic structure was created. The model was analyzed and investigated with finite element method to explore the influential factors such as dimensional distribution of vessel, blood perfusion rate and external heat source for the 3D temperature field. The simulation results were consistent with the experimental data derived from Pennes. The model well reflects the regional difference of tissue temperature caused by the irregular distribution of vessel, and provides temperature guidance for tumor thermotherapy.
5.Lower respiratory tract of pneumoconiosis on fosfomycin antibacterial activity in vitro of fosfomycin to infected in coal worker pneumoconiosis in vitro antibacterial activity.
Pei-Yue LIU ; De-Quan GU ; Kai-Hui ZHANG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2011;29(7):547-548
Acinetobacter Infections
;
microbiology
;
Acinetobacter baumannii
;
drug effects
;
isolation & purification
;
Anthracosis
;
microbiology
;
Anti-Bacterial Agents
;
pharmacology
;
Drug Resistance, Bacterial
;
Fosfomycin
;
pharmacology
;
Humans
;
Imipenem
;
pharmacology
;
Pneumonia, Bacterial
;
microbiology
6.Expression and Characterization of the Recombinant Epitopes of HSV-gB and HSV-gD Protein
Jingyi GAO ; Yue WANG ; Yuji ZHAO ; Kai FANG ; Jinsong ZHANG
Journal of China Medical University 2010;(3):181-183
Objective To prepare the recombinant epitopes of HSV-gB and HSV-gD protein and provides a new antigen protein for the development of herpes simplex virus(HSV)vaccine.Methods The epitopes of HSV-gB and HSV-gD protein were analyzed by epitope prediction software.A novel gene named X which encoded 9 predicted epitopes of HSV-Gb and HSV-gD protein was designed and synthesized using chemical method.X gene was cloned into vector PET-28a(+),expressed in Escherichia cob' BL21(DE3),and analyzed by Western blot.Results X gene was successfully designed and expressed in Escherichia coli BL21(DE3).Western blot analysis showed that recombinant X protein,which was with His marker,can be detected by anti-His antibody.Conclusion In this study we establish a newmethod to express recombinant epitope protein,which may be a new protein for developing vaccine against HSV infection.
7.Research of the image processing in dynamic flatness detection based on improved laser triangular method
Hongzhe XU ; Kai LIU ; Xiaohui PENG ; Pan LI ; Yue LI
Journal of Pharmaceutical Analysis 2008;20(3):168-171
As a commonly used non-contact flatness detection method, laser triangular detection method is designed with low cost, but it cannot avoid measurement errors caused by strip steel vibration effectively. This paper puts forward a dynamic flatness image processing method based on improved laser triangular detection method. According to the practical application of strip steel straightening, it completes the image pre-processing, image feature curve extraction and calculation of flatness elongation using digital image processing technology. Finally it eliminates elongation measurement errors caused by the vibration.
8.Delayed treatment of 51 pediatric displaced femoral neck fractures
Pengfei ZHENG ; Li JU ; Jie CHEN ; Kai TANG ; Yue LOU
Chinese Journal of Orthopaedic Trauma 2016;18(5):375-380
Objective To compare open versus closed reduction in treatment of children with displaced femoral neck fracture whose reduction is delayed by more than 24 hours.Methods We retrospectively reviewed 51 children who had been treated at our department for femoral neck fracture between May 2005 and May 2012 after their reduction had been delayed for more than 24 hours.They were 37 boys and 14 girls,1.7 to 15.5 years of age (average,9.1 years).According to Delbet's classification,27 cases belonged to type Ⅱ,18 to type Ⅲ,and 6 to type Ⅳ.Of them,18 underwent closed reduction and 33 open reduction.Their complications were recorded in detail.Their therapeutic results were evaluated according to Ratliff's criteria and compared between the 2 methods of reduction.Results The 51 children were followed up for an average of 36.7 months (range,from 17 to 61 months).Anatomic reduction was achieved in 6 cases in the closed reduction group (33.3%) and 29 cases in the open reduction group (87.9%),respectively.All fractures healed after an average of 10.9 weeks (range,from 9 to 13 weeks),with one exception of nonunion in the closed reduction group.The incidence of femoral head necrosis in the closed reduction group (27.8%,5/18) was significantly higher than that in the open reduction group (15.2%,5/33) (P < 0.05).According to the Ratliff's evaluation at the final follow-ups,the good to excellent rate in the closed reduction group(66.7%,12/18) was significantly lower than that in the open reduction group (84.8%,28/33) (P <0.05).Coxa vara occurred in 3 children in the closed reduction group but in none in the open reduction group.Conclusion Open reduction with internal fixation may lead to better outcomes than closed reduction in the treatment of children with displaced femoral neck fracture whose reduction is delayed by more than 24 hours,probably because open reduction can result in better reduction quality.
9.Analysis on influential factors in China's exports of primary and semi-finished products of traditional Chinese medicine to ASEAN.
Yun-Xu QIAN ; Yue YANG ; Wei ZHAO ; Kai-Shun BI
China Journal of Chinese Materia Medica 2014;39(7):1321-1325
Two regression models, based on panel data over the period of 2000-2011, are built and used to analyze what factors determine China's exports of primary and semi-finished products of traditional Chinese medicine to ASEAN. The results indicate that, China GDP, the ratio of ASEAN to China GDP per capita, average export price, the ratio of state-owned assets to total assets, have a significant positive influence on the export volumes of primary products of Chinese medicine. At the same time, RMB appreciation, the ratio of three kinds of foreign-invested assets to total assets, China-ASEAN Early Harvest Program, ASEAN-China Free Trade Area have a significant negative influence. In respect of the export volumes of semi-finished products of Chinese medicine, the significant influential factors are ASEAN GDP and the ratio of ASEAN to China GDP per capita. The former is positive and the latter is negative. In order to optimize the commodity composition of experts, it is needed to increase export volumes of both primary and semi-finished products of Chinese medicine. According to the analysis above, some proposals are put forward, such as, improving the performance of foreign capital, playing an exemplary and leading role in technological innovation by state-owned enterprises, taking advantage of bargaining power of suppliers, increasing outward foreign direct investment.
China
;
Commerce
;
Drugs, Chinese Herbal
;
chemistry
;
economics
;
Europe, Eastern
;
Medicine, Chinese Traditional
;
economics
;
standards
;
Quality Control
10.Effect of Sarcandra Glabra on the expression of TGF-β1/Smads in miniature pig of radiation-induced lung injury
Kai HU ; Haiying YUE ; Wenqi LIU ; Feifei LIANG ; Rensheng WANG
Chinese Journal of Radiological Medicine and Protection 2016;36(3):178-185
Objective To study the effect of Sarcandra Glabra on the expression of signal transduction molecules of TGF-β1/Smads signaling pathway in miniature pig of radiation-induced lung injury.Methods 75 miniature pigs were divided into control group,radiation group and radiation plus medication group randomly.At 1 week before exposure of right lung with 15 Gy γ-rays,the miniature pigs in radiation plus medication group were given Sarcandra glabra,while those in the other groups received an equal amount of saline.Right lung were taken at weeks 2,4,8,12 and 24 after irradiation,the pathological changes in the lung tissue were observed by HE staining,and the expression of mRNA and protein of TGF-β1,Smad2,Smad3,and Smad7 were detected by real-time PCR and western blotting,respectively.Results Sarcandra glabra reduced the inflammation and fibrosis of the lung tissue in miniature pig after irradiation.Compared with control group,the expressions of TGF-β1 and Smad3 were significantly increased at 2 weeks after irradiation(P < 0.05),Smad2 and Smad7 were increased at 8 and 12 weeks after irradiation(P < 0.05),respectively,in the radiation group.Compared with the radiation group,the expressions of TGF-β1 and Smad2 were significantly decreased(P < 0.05) from the fourth and eighth week,respectively,Smad3 had no obvious change while Smad7 was significantly increased from the second week in the radiation plus medication group (P < 0.05).Conclusions Sarcandra Glabra plays protective effect on radiation-induced lung injury in miniature pig by regulating TGF-β1,Smad2 and Smad7 expressions in the TGF-β1/Smads signaling pathway.