1.Gut barrier dysfunction in severe acute pancreatitis
Parenteral & Enteral Nutrition 2004;0(06):-
In recent years,some investigations show that gut barrier dysfunction induced by severe acute pancreatitis was an important factor to determine the prognosis. Consequently, pathogenesis, monitoring standard was and treament of pancreatitis associated gut barrier dysfunction are becoming hot spots.
2.Laparoscopy in treatment of renal cysts
Hong-Yi DING ; Kai-Hen LI ; Zheng-Kai WU ;
Chinese Journal of Primary Medicine and Pharmacy 2006;0(09):-
Objective To evaluate the effect of laparoscopy in treatment of renal cysts.Methods Twenty- eight and thirty-five patients with renal cysts were performed with transperituneal and retroperitonel laparoscopy,re- spectively.Results A total of 62 patients were treated successfully,the average operation time was 60 minutes,no complications presented,and there was no recurrence in follow-up.Conclusion Laparoseopy survey had the advan- tages of less trauma and fewer complications and rapid recovery in treatment of renal cysts,which was suggested for clinical applications.
3.Characteristics of radionucilde bone imaging in patients of lung cancer with bone metastases
Zhengqiang DING ; Kai YIN ; Jiang ZHANG
Chinese Journal of Postgraduates of Medicine 2010;33(28):12-14
Objective To explore radionuclide bone imaging characteristics of lung cancer patients and evaluate the clinical significance of bone imaging in the diagnosis of lung cancer patients with bone metastases.Methods One hundred and seventy-seven patients with diagnosed lung cancer were examined by 99mTc -MDP bone imaging,and the symptoms,sites,quantity and pathological types of bone metastases were reviewed and analyzed.Results Total bone metastases ratio of lung cancer was 45.8%(81/177),and 85.2 % (69/81) patients had multiple bone metastases.There was a statistical significance of bone metastases in adenocarcinoma patients (69.0%,40/58),compared with patients of other types of lung cancer[squamous cell cancer (41.3%,19/46),small cell cancer ( 32.5%,13/40),undifferentiated carcinoma ( 27.3%,9/33)](P<0.05).Bone metastases happened in 526 places: thoracic bones 212 places (40.3%),vertebras 168 places (31.9%),pelvic bones 73 places (13.9%),extremities 62 places (11.8%),and skull 11 places (2.1%).Conclusions Multiple bone metastases is more frequent in lung cancer patients.The most frequent metastatic sites are thoracic bones and vertebras.Bone metastases of adenocarcinoma is more easily than other types of lung cancer.All the patients with lung cancer should perform radionuclide bone scan,which is significant for staging,selecting therapy methods and the evaluating prognosis of the disease.
4.Laparoscopic Subtotal Cholecystectomy:Report of 168 Cases
Wu JI ; Lingtang LI ; Kai DING
Chinese Journal of Minimally Invasive Surgery 2001;0(04):-
Objective To investigate the feasibility and technique of laparoscopic subtotal cholecystectomy(LSC).Methods Totally 168 patients were converted to LSC because of failure in laparoscopic cholecystectomy(LC).During the LSC,the Calot's triangle was separated and then the Hartmann's pouch was incised to decreased the intracystic pressure for the removal of the stones.Results Among the cases,5 patients were converted to open surgery for subtotal resection of the gallbladder.LSC was completed after clipping the cystic duct and artery in 122 patients;in the other 41 cases,the gallbladder was cut at the Hartmann's pouch to clip the bile duct and artery or suture the neck of the gallbladder,and then LSC was performed.The median operation time was(65.5?15.2)min,and the intraoperative blood loss was(71.5?15.5)ml.The time to resume the diet was(20.4?6.3)h postoperation.After the operation,7 patients developed local complications(4.2%),and the mean postoperative hospital stay was(4.2?2.6)d.Of the patients,105 were followed up for(25.5?6.5)months,during this period,5 patients had dyspepsia,3 had right shoulder pain,and 9 had right hypochondrium pain.Conclusions LSC is feasible for patients with complicated cholecystitis.It is important to control the perioperative hemorrhage and bile leakage.
5.Observation on therapeutic effect of electroacupuncture plus acupoint-injection for nerve root sciatica
Kai LI ; Xinyin XU ; Deguang DING
Journal of Acupuncture and Tuina Science 2015;(1):32-35
Objective:To observe the clinical effects of electroacupuncture (EA) plus acuoint-injection for nerve root sciatica.
Methods:A total of 114 cases were randomly divided into an observation group and a control group, 57 cases in each group. The observation group was given EA plus acupoint-injection therapy with Cobamamide. The control group was given oral administration of Diclofenac Sodium Sustained-release Tablets plus muscular injection of Cobamamide. After one-course treatment, the clinical effects were compared between the two groups.
Results:The total effective rate was 96.5%in the observation group and 91.2%in the control group, without a statistical significance in the difference between the two groups (P>0.05). The curative rate was 57.9%in the observation group and 21.1% in the control group, with a statistical significance in the difference between the two groups (P<0.05). In the follow-up on the fourth day after the treatment, the recurrence rate was 23.1%in the observation group and 47.9%in the control group, with statistical difference between the two groups (P<0.05).
Conclusion: EA plus acupoint-injection therapy for sciatica of nerve roots is remarkable in the clinical effect and needs promotion in clinic.
6.The use of enteral nutritional support in treating superior mesenteric artery syndrome
Kai DING ; Zhiming WANG ; Zhiwei JIANG
Parenteral & Enteral Nutrition 1997;0(02):-
Objective:To observe the role of enteral nutritional support in treating superior mesenteric artery syndrome. Methods: Enteral nutritional support was used in two patients with superior mesenteric syndrome after percutanous endoscopic jejunostomy.Enteral nutrition was used for 69 days and 180 days.The symptoms were observed.Body weight and index of nutrition were measured.Results: After enteral nutritional support,symptoms of two patients disappeared.Body weight and fibronectin and prealnumin increased.Conclution: Enteral nutritional support is one of effective methods of treating superior mesenteric artery syndrome.
7.Clinical study of percutaneous endoscopic gastrostomy for long-term enteral nutrition in patients with cancers of head and neck
Zhiwei JIANG ; Zhiming WANG ; Kai DING
Medical Journal of Chinese People's Liberation Army 1982;0(01):-
Objective To evaluate percutaneous endoscopic gastrostomy (PEG) for long-term enteral nutrition in patients with cancers of head and neck. Methods PEGs were performed for 12 patients with head and neck cancers, the indication for which included serious buccal mucositis, difficulty in swallowing, anorexia, and obstruction of the digestive tract. Before PEG and 8 weeks after PEG, serum concentrations of total protein and albumin of the patients were measured, body composition including body weight, free fat mass, and fat mass were measured by bioelectric impedance analysis (BIA), and Karnofsky performance score ( KPS) was evaluated. Results After enteral nutrition for 8 weeks through PEG, the serum concentrations of total protein and albumin of the patients increased significantly (63.8?0.3g/L vs 57.4?0.2g/L, P
8.Neuroprotective Mechanism of Neuroglobin
Kai-Dong LIU ; Ding-Biao ZHOU ; Ai-Jia SHANG ;
International Journal of Cerebrovascular Diseases 2006;0(10):-
Neuroglobin is a newly discovered member of globulin family.It has neuronprotec- tive effect under the hypoxic and ischemic conditions.In order to make the acting mechanism of globulin clear,many theories have been raised,and corresponding experiments have been done. This article reviews the latest advances systematically in this field,and puts forward possible research directions in the future.
9.Isolation of a new isoflavone from soybean germ
Deping XU ; Kai XIAO ; Wenying GU ; Xiaolin DING ;
Chinese Traditional and Herbal Drugs 1994;0(12):-
Object To separate and characterize the chemical constituents of soybean germ Methods Column chromatogram, MS spectroscopy, and nuclear magnetic resonance spectroscopy were employed Results Two new isoflavones were isolated from soybean germ They were isomer and relative molecular weight was 564 Compound Ⅰ was 6″ ? D arabinose genistin, compound Ⅱ was 6″ ? D xylose genistin Conclusion The two new isoflavones are first discovered in soybean
10.Tumor-associated macrophages in immune microenvironment of lung cancer
Yihui DING ; Kai ZHANG ; Yue HU ; Li LIU
Journal of International Oncology 2014;41(11):830-833
With the research on tumor immunity and tumor immunosuppression development,immunotherapies for lung cancer has become a research hotspot.Tumor immune microenvironment plays an important role in tumor genesis,development and metastasis of lung cancer.Tumor-associated macrophages (TAMs) are the dominant leukocyte population found in immune microenvironment of lung cancer.The relationship between TAMs and lung cancer becomes clear with further research.TAMs may become the new target of lung cancer immunotherapy.