1.RELATIONSHIP BETWEEN HEART RATE VARIABILITY DURING EXERCISE AND VENTILATORY THRESHOLD
MITSURU TABUSADANI ; YUKIKO HAYASHI ; KIYOKAZU SEKIKAWA ; KOUTARO KAWAGUCHI ; KIYOSHI ONARI ; KAZUNORI KOBAYASHI
Japanese Journal of Physical Fitness and Sports Medicine 2001;50(2):185-192
The aim of this study was to investigate the relationship between heart rate variability (HRV) during exercise and ventilatory threshold (VT), using the MemCalc system which is superior in spectral analysis. Nine healthy male subjects with no cardiopulmonary disease performed an exercise test to exhaustion to determine VT on a bicycle ergometer. Low frequency (LF : 0.04-0.15 Hz), high frequency (HF : 0.15-0.40Hz) and LF/HF ratio power spectra were calculated by maximum entropy method (MEM) spectral analysis, using the MemCalc system. In each case, when the subject started exercise, the HF component declined rapidly during the first 30 seconds ; and compared to the resting value, it declined to approximately 5 % at VT. The possibility of using this phenomenon as a criterion for setting intensity of exercise is tinder consideration. The LF/HF ratio showed different patterns of variation among the subjects. A significant linear relationship was seen between the declining rate of the HF component and VT (r=0.93, p<0.001), suggesting a corres pondence between the heart's capability of adjusting to maintained exercise and high endurance capacity.
2."Mini-Flow-Through" Deep Inferior Epigastric Perforator Flap for Breast Reconstruction with Preservation of Both Internal Mammary and Deep Inferior Epigastric Vessels.
Toshihiko SATAKE ; Jun SUGAWARA ; Kazunori YASUMURA ; Taro MIKAMI ; Shinji KOBAYASHI ; Jiro MAEGAWA
Archives of Plastic Surgery 2015;42(6):783-787
This procedure was developed for preservation of the rectus muscle components and deep inferior epigastric vessel after deep inferior epigastric perforator (DIEP) flap harvesting. A 53-year-old woman with granuloma caused by silicone injection underwent bilateral nipple-sparing mastectomies and immediate reconstruction with "mini-flow-through" DIEP flaps. The flaps were dissected based on the single largest perforator with a short segment of the lateral branch of the deep inferior epigastric vessel that was transected as a free flap for breast reconstruction. The short segments of the donor deep inferior epigastric vessel branch are primarily end-to-end anastomosed to each other. A short T-shaped pedicle mini-flow-through DIEP flap is interposed in the incised recipient's internal mammary vessels with two arterial and four concomitant venous anastomoses. Although it requires multiple vascular anastomoses and a short pedicle for the flap setting, the mini-flow-through DIEP flap provides a large pedicle caliber, enabling safer microsurgical anastomosis and well-vascularized tissue for creating a natural breast without consuming time or compromising the rectus muscle components and vascular flow of both the deep inferior epigastric and internal mammary vessels.
Breast*
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Female
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Free Tissue Flaps
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Granuloma
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Humans
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Mammaplasty*
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Mastectomy
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Mastectomy, Subcutaneous
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Microsurgery
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Middle Aged
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Perforator Flap*
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Silicon
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Silicones
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Tissue Donors
3.Epidemiology of vaccine-preventable diseases in Japan: considerations for pre-travel advice for the 2019 Rugby World Cup and 2020 Summer Olympic and Paralympic Games
Matthew M Griffith ; Munehisa Fukusumi ; Yusuke Kobayashi ; Yusuke Matsui ; Shingo Nishiki ; Reiko Shimbashi ; Saeko Morino ; Tomimasa Sunagawa ; Keiko Tanaka-Taya ; Tamano Matsui ; Kazunori Oishi
Western Pacific Surveillance and Response 2018;9(2):26-33
Introduction:
In 2019 and 2020, Japan will host two international sporting events estimated to draw a combined 22 million visitors. Mass gatherings like these ones increase the risk of spread of infectious disease outbreaks and international transmission. Pre-travel advice reduces that risk.
Methods:
To assist ministries of health and related organizations in developing pre-travel advice, we summarized national surveillance data in Japan (2000–2016, to the extent available) for rubella, invasive pneumococcal disease, measles, non-A and non-E viral hepatitis, hepatitis A, invasive Haemophilus influenzae disease, tetanus, typhoid fever, invasive meningococcal disease, Japanese encephalitis, influenza, varicella, mumps and pertussis by calculating descriptive statistics of reported cases and reviewing trends. (See Annex A for details of reviewed diseases.)
Results:
Our findings showed notable incidences of rubella (1.78 per 100 000 person-years), influenza (243.5 cases per sentinel site), and mumps (40.1 per sentinel site); seasonal increases for influenza (November–May) and Japanese encephalitis (August–November); and a geographical concentration of Japanese encephalitis in western Japan. Measles cases decreased from 11 013 in 2008 to 35 in 2015, but outbreaks (n = 165 cases) associated with importation occurred in 2016. Though invasive meningococcal disease incidence was only 0.03 per 100 000, international transmission occurred at a mass gathering in Japan in 2015.
Discussion
Ministries of health and related organizations should use these findings to develop targeted pre-travel advice for travellers to the 2019 Rugby World Cup and the 2020 Summer Olympic and Paralympic Games, especially for mumps, measles, rubella, influenza, and meningitis. Travellers with increased exposure risk should also be advised about hepatitis A and Japanese encephalitis.
4.Evaluation of the results of oral food challenges conducted in specialized and general hospitals
Kazunori SAKAI ; Kemal SASAKI ; Tomoko FURUTA ; Shiro SUGIURA ; Yukari WATANABE ; Takae KOBAYASHI ; Takashi KAWABE ; Masashi MORISHITA ; Kumiko NAKANISHI ; Komei ITO
Asia Pacific Allergy 2017;7(4):234-242
BACKGROUND: Oral food challenge (OFC) tests are conducted in both specialized institutions and general hospitals. We aimed to compare the severity of the conditions of the patients between these 2 types of institutions in order to consider the role of such institutions in society. OBJECTIVE: We evaluated the results of OFC tests for hen's egg, cow's milk, and wheat that were conducted in a specialized institution (Aichi Children's Health and Medical Center [ACHMC], n = 835) and in 4 general hospitals (n = 327) in Aichi prefecture, Japan. METHODS: The symptoms provoked were scored using the total score (TS) of the Anaphylaxis Scoring Aichi scoring system in combination with the total ingested protein dose (Pro) before the appearance of allergic symptoms. RESULTS: The total ingested dose of the challenge-positive patients in ACHMC was significantly less than that in the general hospitals (p < 0.01). The median TS of the provoked symptoms in ACHMC and the general hospitals did not differ to a statistically significant extent in the hen's egg or cow's milk challenges; however, the median TS in ACHMC was significantly lower than that in the general hospitals for the wheat challenge (p = 0.02). The median TS/Pro values in ACHMC were almost identical to the upper 25% of the TS/Pro values in the general hospitals, suggesting that the specialized institution usually managed more severe patients. CONCLUSION: The specialized institution performed OFC tests at a lower threshold dose, but provoked similar TSs to the general hospitals. This evaluation may help in optimizing the distribution of patients to general hospitals and specialized institutions.
Anaphylaxis
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Child Health
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Hospitals, General
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Hospitals, Special
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Humans
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Japan
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Milk
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Ovum
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Severity of Illness Index
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Triticum
5.Exposure to H1 genotype measles virus at an international airport in Japan on 31 July 2016 results in a measles outbreak
Aika Watanabe ; Yusuke Kobayashi ; Tomoe Shimada ; Yuichiro Yahata ; Ayako Kobayashi ; Mizue Kanai ; Yushi Hachisu ; Munehisa Fukusumi ; Hajime Kamiya ; Takuri Takahashi ; Yuzo Arima ; Hitomi Kinoshita ; Kazuhiko Kanou ; Takehito Saitoh ; Satoru Arai ; Hiroshi Satoh ; Hideo Okuno ; Saeko Morino ; Tamano Matsui ; Tomimasa Sunagawa ; Keiko Tanaka-Taya ; Makoto Takeda ; Katsuhiro Komase ; Kazunori Oishi
Western Pacific Surveillance and Response 2017;8(1):37-39
6.Preparation for mass gathering events from the perspective of a non-host country: the experience of Japan during the 2018 PyeongChang Olympics and Paralympic Winter Games
Kazuaki Jindai ; Takuya Yamagishi ; Munehisa Fukusumi ; Shingo Nishiki ; Yusuke Kobayashi ; Yusuke Matsui ; Tamano Matsui ; Kazunori Oishi
Western Pacific Surveillance and Response 2019;10(1):39-42
The World Health Organization recommends that countries or organizations that host mass gatherings plan ahead and prepare for possible public health events to ensure a safe environment for local residents, participants and travellers.1 Public health events during mass gatherings can also affect non-host countries. There are numerous reports of the spread of infectious diseases by travellers returning from mass gatherings,2 which can potentially pose the risk of an outbreak of new infectious diseases to travellers’ home countries. With more frequent travel across borders, it is prudent that non-host countries prepare for mass gathering events.
7.Serial Changes in Score on the Japanese Version of the Trail Making Test (TMT-J) After Minor Ischemic Stroke
Miho YOSHIOKA ; Zen KOBAYASHI ; Kaori KATO ; Keisuke INOUE ; Masaki HAKOMORI ; Kazunori TOYODA ; Yoshiyuki NUMASAWA ; Toshiya MATSUDA ; Yuki KATAYAMA ; Shoichiro ISHIHARA ; Hiroyuki TOMIMITSU ; Shuzo SHINTANI
Journal of the Japanese Association of Rural Medicine 2020;69(4):351-
The Trail Making Test (TMT) is a widely used measure of attention impairment. The time needed to complete the TMT (TMT score) is longer with greater impairment of attention in patients with brain diseases. TMT score becomes large in a proportion of patients with minor ischemic stroke. The Japanese version of the TMT- (TMT-J) was published in 2019. The purpose of this study was to clarify serial changes in TMT-J scores in patients with minor ischemic stroke. We retrospectively reviewed the TMT-J scores in those patients who completed the test both 8-14 days and 29-35 days after stroke onset. On initial evaluation, 1 of 21 patients could not complete TMT-J Part A. TMT-J Part A scores had a mean of 67 s and were abnormally large in 45% of the 20 patients who completed this part. Two of these 20 patients could not complete TMT-J Part B. TMT-J Part B scores had a mean of 135 s and were abnormally large in 61% of the 18 patients who completed this part. On second evaluation, scores on Part A and Part B improved in 76% and 73% of patients, respectively. This study demonstrated that abnormal TMT-J scores 8-14 days after onset of minor ischemic stroke improved over time in most patients.
8.Asian Society of Gynecologic Oncology International Workshop 2018
Tae Wook KONG ; Hee Sug RYU ; Seung Cheol KIM ; Takayuki ENOMOTO ; Jin LI ; Kenneth H KIM ; Seung Hyuk SHIM ; Peng Hui WANG ; Suwanit THERASAKVICHYA ; Yusuke KOBAYASHI ; Maria LEE ; Tingyan SHI ; Shin Wha LEE ; Mikio MIKAMI ; Satoru NAGASE ; Myong Cheol LIM ; Jianliu WANG ; Sarikapan WILAILAK ; Sang Wun KIM ; Sook Hee HONG ; David SP TAN ; Masaki MANDAI ; Suk Joon CHANG ; Ruby Yun Ju HUANG ; Kimio USHIJIMA ; Jung Yun LEE ; Xiaojun CHEN ; Kazunori OCHIAI ; Taek Sang LEE ; Bingyi YANG ; Farhana KALAM ; Qiaoying LV ; Mohd Faizal AHMAD ; Muhammad Rizki YAZNIL ; Kanika Batra MODI ; Manatsawee MANOPUNYA ; Dae Hoon JEONG ; Arb aroon LERTKHACHONSUK ; Hyun Hoon CHUNG ; Hidemichi WATARI ; Seob JEON
Journal of Gynecologic Oncology 2019;30(2):e39-
The Asian Society of Gynecologic Oncology International Workshop 2018 on gynecologic oncology was held in the Ajou University Hospital, Suwon, Korea on the 24th to 25th August 2018. The workshop was an opportunity for Asian doctors to discuss the latest findings of gynecologic cancer, including cervical, ovarian, and endometrial cancers, as well as the future of fertility-sparing treatments, minimally invasive/radical/debulking surgery, radiotherapy, chemotherapy, targeted therapy, and immunotherapy. Clinical guidelines and position statement of Asian countries were presented by experts. Asian clinical trials for gynecologic cancers were reviewed and experts emphasized the point that original Asian study is beneficial for Asian patients. In Junior session, young gynecologic oncologists presented their latest research on gynecologic cancers.
Antineoplastic Agents
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Asian Continental Ancestry Group
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Drug Therapy
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Education
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Endometrial Neoplasms
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Female
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Gyeonggi-do
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Humans
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Immunotherapy
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Korea
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Ovarian Neoplasms
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Radiotherapy
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Uterine Cervical Neoplasms