No abstract available.
Arthritis, Juvenile* ; Rheumatoid Factor*

Recently, gout prevalence is increasing, but in Vietnam the knowledge of gout is not enough. Objectives: (1) Describe clinical X-ray manifestations of bone and joint damage related to chronic gout. (2) Identify suggestive factors to make diagnosis of bone and joint damage related to chronic gout. Methods: The cross-study included 54 patients with chronic gout presented in the Rheumatology Department of Bach Mai Hospital from March-2003 to June-2004. All of them were diagnosed gout according to the criteria of Bennett and Wood-1968 and had tophi nodules. Results: The common findings are polyarthritis (79.6%), lower limbs are involved more common than upper limbs (75-80% of patients had ankle, knee, first metatarsophalangeal joint arthritis) and symmetric arthritis (60% to 70%). All patients had a history of acute gout. 80% of patients had chronic gout presented in X-ray images, including joint space narrowing, erosion, new bone formation at the edge of a gradually expanding tophus. Important factors can be considered of chronic gout were male, middle age, symmetric arthritis of lower limbs, tophi nodules. Conclusions: Suggestive factors and X-ray of bone and join contribute to earlier diagnosis of bone and joint damage in chronic gout.
Gout ; Arthritis ; Juvenile Rheumatoid ; Bone and Bones

No abstract available.
Arthritis, Juvenile Rheumatoid ; Herpesvirus 4, Human

Arthritis, Juvenile/complications* ; Humans ; Rheumatoid Nodule

Juvenile idiopathic arthritis (JIA) is a chronic inflammation of joints in pediatric patients. Assessment of JIA disease activity is very difficult, because children cannot definitely describe their pain by themselves due to development of cognitive function during the pediatric period. Assessment of JIA disease activity is useful for quantitative measurement of patient status, monitoring therapeutic response, and disease course over time. This article reviewed objective assessment tool for JIA disease activity and described differences in assessment between adult rheumatoid arthritis and JIA.
Adult ; Arthritis, Juvenile* ; Arthritis, Rheumatoid ; Child ; Humans ; Inflammation ; Joints

Juvenile rheumatoid arthritis (JRA) is basically the same disease as rheumatoid arhritis in the adult. However juvenile rheumatoid arthritis has many features that differ from rheumatoid arthritis in the adult, and since the onset of the disease occurs before the age of puberty, variable alterations in growth may occur. In this study, fifty cases of juvenile rheumatoid arthritis treated at Severance Hospital from January 1970 to December 1977 were analysed clinically and the following results were obtained. 1. By classification, the polyarticular type (46%) was most frequent, followed by the pauciarticular type (34%) and systemic type (20%) in order. 2. The most frequent joint affected was the knee (82%) followed by the ankle (60%), hand (22%), wrist (20%), etc. 3. The extra-articular manifestations on admission were high fever (40%), rash (16%), carditis (14%), lymphadenopathy (14%), etc. 4. Laboratory findings on admission showed increased ESR (88%), positive rheumatoid factor (15.5%), positive ANA (16.6%), etc. 5. Clinical symptoms were managed medically and surgically with aspirin, salicylates and steroids, physical therapy, and synovectomy.
Adolescent ; Arthritis, Juvenile Rheumatoid/classification ; Arthritis, Juvenile Rheumatoid/epidemiology* ; Child ; Child, Preschool ; Female ; Follow-Up Studies ; Human ; Korea ; Male

Secondary amyloidosis is one of the most serious complications in chronic inflammatory diseases such as rheumatoid arthritis. The extracellular deposit of aggregates of amyloid leads to target organ dysfunction. The mainstay treatment of secondary amyloidosis is the control of underlying disease activity. Many reports have reported that TNF-alpha inhibitors improve clinical outcomes. Here, we encountered a 34-year-old patient with juvenile rheumatoid arthritis who developed secondary amyloidosis despite treatment with TNF-alpha inhibitors. We present this case and include a review of the literature.
Adult ; Amyloid ; Amyloidosis ; Arthritis, Juvenile Rheumatoid ; Arthritis, Rheumatoid ; Humans ; Tumor Necrosis Factor-alpha

Multiple sclerosis (MS) is an immune-mediated, inflammatory demyelinating disease of the central nervous system. The coexistence of multiple sclerosis and rheumatoid arthritis is very rare. This rare association is interesting due to the overlapping pathophysiological similarities of T-cells and tumor necrosis factor-alpha (TNF-alpha) in both diseases. We report a case of a Korean 10 year old girl with multiple sclerosis, who after 3 years developed a clinical and serological manifestation of juvenile rheumatoid arthritis.
Arthritis, Juvenile Rheumatoid ; Arthritis, Rheumatoid ; Central Nervous System ; Demyelinating Diseases ; Humans ; Multiple Sclerosis ; Sclerosis ; T-Lymphocytes ; Tumor Necrosis Factor-alpha

Pachydermodactyly is a form of digital dermal fibromatosis of unknown etiology, characterized by asymptomatic soft tissue swelling on the lateral aspects of the proximal interphalangeal joints of the hands. It usually affects young men and often associated with repetitive mechanical trauma. As a rule, it is a benign condition and a specific therapy or extensive investigation is not necessary in most cases. However, pachydermodactyly is not well recognized by physician. So it can be confused with other rheumatic conditions, such as rheumatoid arthritis or juvenile idiopathic arthritis. A prompt diagnosis is crucial for preventing inappropriate or possible toxic treatment. We describe a case of pachydermodactyly in a 20-year-old military man, who had painless swellings of the hand joints.
Arthritis, Juvenile ; Arthritis, Rheumatoid ; Diagnosis ; Fibroma ; Hand ; Hand Joints ; Humans ; Joints ; Male ; Military Personnel ; Young Adult

Chronic arthritis, the most common chronic rheumatic disease of childhood, is one of the most frequent chronic illness of children and an important cause of short and long term disability. It is not a single disease, but a group of related, genetically heterogeneous, phenotypically diverse immunoinflammatory disorders that affect the joints and other structures, possibly activated by contact with external antigens. Since its introduction in 1994, the term Juvenile Idiopathic Arthritis (JIA) has largely supplanted the terms Juvenile Chronic Arthritis and Juvenile Rheumatoid Arthritis. However, it is necessary to understand the older classifications in order to interpret the literature on the subject. Each subtype of JIA is to provide a general introduction.
Arthritis ; Arthritis, Juvenile Rheumatoid ; Child ; Chronic Disease ; Humans ; Joints ; Rheumatic Diseases