1.Data curation and its application in special libraries
Chinese Journal of Medical Library and Information Science 2014;(9):41-44
After the concept of data curation and its application in foreign countries were described , the key points of data curation for data service in special libraries and related problems were analyzed according to the overall needs and changes of users in special libraries.
2.Implementation of information pushing function in mobile library using Drupal+PhoneGap
Ye SU ; Wen HUANG ; Xin SONG ; Juntao MA
Chinese Journal of Medical Library and Information Science 2014;(5):76-80
Drupal, a powerful content management system and content management framework, can provide a visiting interface for the mobile terminal equipments , especially the interface for the mobile APP program .How to imple-ment the information pushing function in mobile library using Drupal+PhoneGap was described by constructing the APP program model for information pushing and browsing in mobile library as an example.
3.Analysis of differentially expressed genes in placental tissues of early-onset severe preeclampsia patients
Yingna SONG ; Jianqiu YANG ; Juntao LIU ; Saijiong HUANG
Chinese Journal of Obstetrics and Gynecology 2014;(7):501-505
Objective To explore the differentially expressed genes (DEG) involved in the pathogenesis of preeclampsia(PE). Methods The gene expression profiles of placental tissues from 7 severe PE patients and 7 preterm controls from June to December 2012 were assessed using microarray. Gene ontology(GO)enrichment analysis and pathway analysis were performed to explore the genes and pathways involved in the pathogenesis of PE. Four DEG involved in these biological processes were further verified by quantitative real-time PCR. Results A total of 308 transcripts were significantly differentially expressed. Of these DEG,81 genes(LEPTIN,PAPPA2,CRH,PLIN2,INHA,BCL6,FLT1,CCR7,etc)were up-regulated,and 227 genes(CXCL12,CXCL9,etc)were down-regulated. GO enrichment analysis indicated that the top 3 GO molecular functions were immune response(GO: 0006955,17 DEG),positive regulation of apoptosis(GO: 0043065,11 DEG)and inflammatory response(GO: 0006954,11 DEG). Pathway analysis showed that the top 3 pathways were cell adhesion molecules(11 DEG),cytokine-cytokine receptor interaction(11 DEG),chemokine signaling pathway(8 DEG). Many genes(LEP,FLT1,TFRC,SH3PXD2A, CYP11A1,SEPP1,and so on)involved in oxidative stress were found to be significantly changed. Of these genes,LEP were significantly up-regulated with a fold change of 61.5. The fold changes of FLT1, SH3PXD2A,SEPP1,CYP11A1,TFRC were 8.6,2.2,-2.0,2.7 and-2.8. Four DEG involved in oxidative stress were further verified by quantitative real-time PCR. Conclusions A DEG signature was identified in severe preeclampsia placentas compared with normal controls. The DEG mainly involved in the molecular mechanisms of immune response,oxidative stress and inflammatory response,and were closely associated with the pathogenesis of PE.
4.Resonance Characteristics of Pre-and Post -UPPP Operation in Patients with OSAHS
Jie OUYANG ; Yongwang HUANG ; Chao LI ; Dehui FU ; Juntao NIU
Journal of Audiology and Speech Pathology 2013;(6):582-584
Objective To study the influence of UPPP on resonance characteristics of four resonance cavity in patients with OSAHS .Methods Using multi-channel voice analysis system to test the cavity resonance character-istics and energy distribution of 36 OSAHS patients (including pre - and post -operative) and 36 normal males when they speak /a:/.The frequency spectrum was 4 000Hz(FR1 ,FR2 ,FR3 ,FR4 ) .Results FR2 energy values of the head cavity and mouth cavity of OSAHS patients heighten significantly after UPPP (P<0 .05);FR1 energy val-ues of head ,mouth and thoracic cavity were higher than that of in normal males'after UPPP(P<0 .05) .FR2 ,FR3 , FR4 energy values of head cavity ,FR2 ,FR3 energy values of mouth cavity ,FR2 energy values of thoracic cavity were lower than those of in normal males'after UPPP(P<0 .05) .Conclusion UPPP surgery removes the obstruction of the upper airway of OSAHS patients and changes the morphology of the pharynx ,thas changes the resonance charac-teristics of the head cavity and oral .
5.Application of CDP technology in protecting data in libraries
Xin SONG ; Wen HUANG ; Juntao MA ; Ye SU
Chinese Journal of Medical Library and Information Science 2014;(8):76-80
After the meaning, features and application models of CDP technology were described, its application in protecting data in libraries was studied with Medical Library of Chinese PLA as an example, showing that CDP technology can effectively protect the data, improve their safety, and insure the stable operation of professional sys-tems in Medical Library of Chinese PLA.
6.MOOC and its application in medical library
Yejia WANG ; Qiusheng DONG ; Wen HUANG ; Juntao MA ; Xin SONG
Chinese Journal of Medical Library and Information Science 2014;(12):21-24
After the definition and emergence of MOOC and its development at home and abroad were described, the position of library under MOOC environment was discussed with stress laid on how to deepen the service in medical library by making use of MOOC and the challenges medical library is faced.
7.Short segment fixation in combination of pedicle screw in injured vertebrae for thoracolumbar fractures
Zhengpin CAO ; Juntao HUANG ; Shikui SU ; Bin LI
Journal of Regional Anatomy and Operative Surgery 2015;(2):143-145
Objective To assess the clinical outcome of short segment fixation in combination of pedicle screw in injured vertebrae for thoracolumbar fractures. Methods Twenty-one cases of thoracolumbar fractures received short segment fixation combined with pedicle screw in injured vertebrae surgery. The protruding after angle correction and vertebral body height recovery situation were measured by X-ray film before and after surgery. Results All the patients were followed up for 6~20 months,achieved good reduction effect. The imaging measure-ment results found that before the operation Cobb’s angle was (26. 4 ± 7. 3),fracture fanterior flange height was (56. 1 ± 12. 5)%. Com-pared with after the operation and the end of follow-up of Cobb’ s and fracture fanterior flange height,the difference had statistical significance (P<0. 05). But between after the operation and the end of the follow-up of Cobb’s and fracture fanterior flange height,the difference had no statistical significance (P>0. 05). Conclusion Short segment fixation in combination of pedicle screw in injured vertebrae can restore the height of vetebra,rectify protrusion deformity,which is an effective method for thoracolumbar fracture.
8.Review of key technologies used in mobile reading service of library
Juntao MA ; Wen HUANG ; Xin SONG ; Ye SU
Chinese Journal of Medical Library and Information Science 2014;(3):34-38
After the key technologies used in mobile reading service of library were compared , the authors pointed out that copyright and privacy protection were the major issues challenging the mobile reading service of library.Its development was prospected .
9.Retrospective analysis of external quality control of blood cotting from 2009 to 2013
Yanping ZHANG ; Juntao HE ; Shan WANG ; Xian ZHANG ; Lei ZHANG ; Jinhua WANG ; Lun HUANG
International Journal of Laboratory Medicine 2015;(4):492-493
Objective To know about recent experience of the quality control of blood clotting,to analyze the reasons for its out-of-control,and then to explore the influencing factors of coagulation tests.Methods According to the testing standards of coagula-tion quality control products of Clinical Laboratory Center,Ministry of Health,each batch of products were taken standardized tests.The external quality control results of blood clotting from 2009 to 2013 were analyzed and counted up combined with the in-ternal quality control and daily work performance.Results The overall performance of external quality control was good (from 2009 to 2013).The total scores in 2009 were 90%,95%,were 100% and 100% in 2010,were 95% and 95% in 2011,were 100%and 85% in 2012,and were 100% and 100% in 2013.Conclusion Laboratory internal quality control should be guaranteed.The quality control of pre-analysis,post and analysis and analysis-in-course can improve clinical coagulation testing quality.
10.Clinical Trial on the Role of Tuina in Rehabilitation Therapy Following Total Hip Replacement
Li GONG ; Juntao YAN ; Zhenan ZHU ; Yuanzhi FAN ; Yin SUN ; Yunhu XI ; Rude HUANG ; Chouping HAN
Journal of Acupuncture and Tuina Science 2010;08(6):384-389
Objective: To observe the clinical effect of tuina in rehabilitation following total hip replacement. Methods: 60 cases were randomly allocated into a treatment group and control group, 30 cases in each group. Cases in the treatment were treated with combined mina and rehabilitation, while cases in the control group were treated with rehabilitation alone. All treatment retained for two weeks. The results were observed 7 d, 2 weeks and 6 weeks following the total hip replacement using Harris scale and Hamilton Anxiety Rating Scale (HAMA).Results: For Harris scale, there were significant intra-group differences in different time frames (P<0.05); there were no statistical differences between the two groups 1 d, 7 d and 6 weeks following the total hip replacement (P>0.05); and there were statistical differences between the two groups 2 weeks following the total hip replacement. For HAMA scale, there were significant intra-group differences in different time frames (P<0.05); there were no significant differences between the two groups 1 d following the total hip replacement; and there were substantial differences between the two groups 7 d, 2 weeks and 6 weeks following the total hip replacement. Conclusion: In a given unit time, combined mina and rehabilitation is superior to rehabilitation alone in improving the patients' post-operative pain, articular range of motion and anxiety.