1.Hot topics in the perioperative nutritional support therapy in abdominal surgery
Chinese Journal of Digestive Surgery 2015;14(5):361-364
Malnutrition is common in the abdominal surgery and affects the recovery of patients.Reasonable nutritional support therapy can improve the prognosis of patients.The nutritional risk screening should be apphed to patients within 24 hours of admission.Patients with the nutritional risk and malnutrition should receive the nutritional support by selecting a good timing and way based on the nutritional support planning.Preoperative fasting all night for the majority of patients is not necessary,patients should be allowed to intake low-concentration liquid diet at hour 2 before anesthesia.Patients with preoperative severe malnutrition should be given 7-10 days of nutritional support therapy.The enteral nutritional therapy was preferred to patients needing postoperative nutritional support therapy,while parenteral nutrition therapy should be supplied to patients with infeasible enteral nutrition or expected target of 60% for enteral nutrition.Individual nutritional support therapy is not necessary for patients without severe concomitant disease.Pharmacological nutrients such as ω-3 polyunsaturated fatty acids and glutamine are beneficial for abdominal surgery and critical patients,which should be used reasonably.
2.Therapeutic Observation of Scraping Therapy plus Yi Yi Ren (Semen Coicis) Congee for Functional Dyspepsia Due to ;Dampness-heat Blocking the Stomach
Shanghai Journal of Acupuncture and Moxibustion 2016;35(10):1203-1205
Objective To observe the clinical efficacy of scraping therapy plus Yi Yi Ren (Semen Coicis) congee in treating functional dyspepsia due to dampness-heat blocking the stomach. Method Sixty-four patients were divided into an observation group and a control group by using the random number table, 32 cases in each group. The observation group was intervened by scraping therapy plus Yi Yi Ren (Semen Coicis) congee, while the control group was by Mosapride citrate dispersible tablets. The two groups were both treated for 4 weeks. The traditional Chinese medicine (TCM) symptom score, Nepean Dyspepsia Symptom Index (NDSI), and Nepean Dyspepsia Life Quality Index (NDLQI) were observed before and after the intervention and the clinical efficacy was evaluated, for comparison and analysis. Result The total effective rate was respectively 93.8%in the observation group and 78.1%in the control group, and the observation group was superior to the control group (P<0.05);after the intervention, the TCM symptom scores and NDSI scores dropped significantly in the two groups (P<0.05,P<0.01), and the NDLQI scores increased significantly in the two groups (P<0.05), and the improvements in the observation group were more significant (P<0.05). Conclusion Scraping therapy plus Yi Yi Ren (Semen Coicis) congee and Mosapride citrate dispersible tablets are both effective in treating functional dyspepsia due to dampness-heat blocking the stomach, while the former one can produce a more significant therapeutic efficacy and improve the symptoms and quality of life in a better way.
3.EFFECT ON THE EXPERIMENTAL RESULTS OF THE CONTENT OF COMPOSITIONS IN RAPD EXPERIMENT OF SOIL CULTURED BACTERIA
Microbiology 1992;0(05):-
The total soil cultured bacterial DNA was extracted by improved CTAB -lysosome-protease K method and was analyzed by random amplified polymorphic D NA markers. The effect of concentration of Mg 2+ , dNTP, DNA templates, pri mers, DNA polymorase and bovine serum albumin on experimental results were teste d and the optimal reaction system of RAPD for soil cultured bacteria was determi ned.
5.Role of Pulmonary Alveolar Macrophage in Lung Injury after Burn—Blast Combined Injury
Chinese Journal of Trauma 1990;0(04):-
In order to clarify the relationship between PAMs and post—trauma lung injury, the H_2O_2 produced by PAMs and catalase activity of bronchoalveolar lavage fluid (BALF) and lung homogenate were measured at hours 6、12、24、48 and 72 after burn、blast injury and burn—blast combined injury in 128 rats, respectively. After trauma, H_2O_2 produced by PAMs was increased compared with PAMs from control lungs, especially in the combined injury groups. The catalase activity of BALF and lung homogenate decreased. The catalase activity in combined injured lungs was the lowest. The results indicated 1. the activation of PAMs might play a role in post—trauma lung injury: 2. the damage of pulmonary antioxidant system after trauma may enhanced the lung injury; 3. the state of PAMs activation and the damage of pulmonary antioxidant system were related to the severity of trauma.
6.Current research of Zevalin and Bexxar in the field of radioimmunotherapy
Fudan University Journal of Medical Sciences 2009;36(6):786-788
Radioimmunotherapy using monoclonal antibodies incorporated with radionuclide has been showed to be an effective agent for refractory non-Hodgkin's lymphoma (NHL). Many anti-CD20 antibodies labeled with radionuclide, such as 90Y-ibritumomab tiuxetan (Zevalin) and 131I-tositumomab tiuxetan (Bexxar), have been reported to be effective for the treatment of patients with relapsed or refractory low-grade, follicular, or transformed NHL. This review summarizes the current advance in clinical trials and studies of Zevalin and Bexxar for the treatment of NHL patients.
7.Recent advances in diagnosis and treatment of autoimmune pancreatitis
Chinese Journal of Hepatobiliary Surgery 2011;17(8):690-694
Autoimmune pancreatitis (AIP), which is always associated with autoimmune manifestations, was introduced in 1995 and has been recognized as a type of chronic pancreatitis. Despite numerous studies in Japan, Europe and the United States in recent years, no consensus has been reached about the diagnostic criteria for AIP that may be difficult to distinguish from pancreatic cancer(PC). Nevertheless, the results find it dramatically responds to steroid therapy.
8.Biological and biomechanical properties of reconstructing anterior cruciate ligament of knee joint
Chinese Journal of Tissue Engineering Research 2005;9(26):265-267
OBJECTIVE: To probe into the function of early exercises on healing of grafts after anterior cruciate ligament (ACL) reconstruction and on motor function recovery of knee joint by summarizing biology and biomechanical properties of ACL reconstruction.DATA SOURCES: The relevant literatures on ACL reconstruction of knee joint and its biomechanical properties were looked up in period of MEDLINE1970-01/2004-01 on computer. Retrieval words: "anterior cruciate ligament, knee joint, biomechanics" only in English.STUDY SELECTION: In initial examination, the complete contents of literatures on ACL reconstruction of knee joint and its biomechanical properties were selected. The controlled papers were randomized, for those written by the same writer, the papers with the most cases were included.Comprehensive and Mete analyzed papers were excluded. Quality evaluation was mainly based on the reality of observed data and rigor of investigation and application.DATA EXTRACTION: Fourty-six papers on ACL reconstruction of knee joint and its biomechanical properties were looked up totally, of which, 29papers were tallied with inclusive criteria, 17 papers were excluded, 9 papers were the analysis on small samples and 8 papers referred to comprehensive and Meta analysis.DATA SYNTHESIS: By understanding biomechanical properties of normal ACL it is to implement reconstruction measures and plan for rehabilitation. Animal experiment after ACL reconstruction suggests that the motor function recovery of knee joint is not satisfactory, but the results of human experiment are superior to animal one. It is indicated in randomized control experiment that immediate weightbearing right after ACL reconstruction will not aggravate knee joint laxity; on the contrary, it is advantageous to alleviate patellar pain.CONCLUSION: Reconstruction of injured ACL fixes knee joints, limits peripheral muscle contraction and results in limited motor function of ligaments, joints and peripheral muscles. Early rehabilitation exercises may alleviate pain, improve articular cartilage metabolism, prevent capsule contracture and benefit recovery of motor function after ACL reconstruction of knee joint.In randomized comparisons of Bear[27], Fischer[28] and Beynnon[29],there is no difference between rehabilitation at home and in hospital after ACL reconstruction with bone-patellar-bone graft.
9.Prognostic significance of the marrow blast decline index in AML (not APL) at the first inductive treatment for 7-10 days
Journal of Leukemia & Lymphoma 2009;18(12):742-743
Objective To investigate relationship of the marrow blast decline index(MBDI)in AML (not APL)at the first inductive treatment for 7-10 days and the prognosis.Methods 109 cases of AML were retrospectively analyzed(not APL),to compare theⅡmarrow blast decline index in AML(not APL)at the first inductive treatment for 7-10 days in the continue relieve group,the relapse group and the non-remission group,analyzed the correlation of the MBDI and continue relapse rate,the MBDI and relapse rate.Results The MBDI mean value is 0.8856 in continue relieve group.significantly higher than that of the relapse group (mean=0.4445)and the non-remission group(mean=0.3903)(P<0.0001).The MBDl positively correlated with continue relapse rate(P<0.01);negatively correlated with relapse rate(P<0.01).Conclusion The marrow blast decline index in AML(not APL) at the first inductive treatment for 7-10 days was significant for early assesment ofthe prognosis.
10.DISTRIBUTION AND QUANTITATIVE STUDY OF CON A RECEPTOR ON THE SURFACE OF HUMAN PERIPHERAL BLOOD LEUCOCYTES
Acta Anatomica Sinica 1957;0(04):-
lymphocyte,and especially the small lymphocytes were moreheavily labeled than the larger ones,and the Con A receptor of NK cell exhibitedpolarization along the cell surface.These results suggest that:1.the extent of ConA receptors was related to the functional activities of the ceils,the more active thecell is,the more the Con A receptors will be;2.the receptors of Con A wereprobably related to the cell recognition,for instance,on the NK cell Con A rece-ptors showed polar distribution;3.the number of receptors of Con A was dependenton the cell differentiation,the more mature the cell is,the more the Con Areceptors are.