Objective To observe the clinical efficacy of JIN'sthree needle acupuncture plus modern nerve facilitation technique in treating infantile cerebral palsy.Method Fifty-two patients were randomized into a treatment group of 26 cases and a control group of 26 cases. The treatment group was intervened by JIN'sthree-needle acupuncture plus modern nerve facilitation technique, while the control group was by bionic electrical stimulation. After 2 treatment courses, the treatment group and control group were compared with each other by the Gross Motor Function Measure (GMFM), time taken for 10 m walk, Berg Balance Scale (BBS), modified Barthel Index (MBI) and therapeutic efficacy.Result After the treatment, the GMFM, time taken for 10 m walk, BBS, and MBI scores were significantly improved in the two groups (P<0.05). There were significant differences in comparing the GMFM, time for 10 m walk, BBS, and MBI scores between the two groups (P<0.05). The total effective rates were respectively 92.3% and 76.9%in the treatment group and control group, and the difference was statistically significant (P<0.05).Conclusion JIN's three-needle acupuncture plus modern nerve facilitation technique can significantly boost the efficacy in treating cerebral palsy.

With the rapid development in science and technology,more and more advanced medical devices have been used in clinical practice.Consequently,the maintenance and management of the devices has become a task of modern hospitals.In this paper,the author discusses some issues for their maintenance and management.

Objective To investigate the current situation of healthcare-associated infection (HAI)management in basic level private medical institutions.Methods 118 basic level private medical institutions in a district of Chengdu were investigated through visiting and questionnaire.Results Of 118 medical institutions,only 2 had HAI manage-ment personnel,4 had HAI management system.22.03% had hand washing facilities in therapeutic rooms and con-sulting rooms,37.29% of institutions stored aseptic items in accordance with the requirements,55.93% of institu-tions disposed medical waste at disposal center;99.15% handled reusable items by users.Conclusion HAI manage-ment status is worried,health administrative department should strengthen support and supervision,especially in-tensified the supervision of private dental clinics.

Objective To explore the effect of flow yoga on balance ability and fear of falling of community patients with stroke.Methods Divided 92 community patients with stroke into the intervention group (46 cases) and the control group (46 cases) randomly,routine community nursing cares were used in the control group,while the flow yoga were used in the intervention group in addition.The berg balance scale,single direct question of fear of falling and modified falls efficacy scale were used to evaluate balance ability and fear of falling after the intervention between the two groups.Results The patients' balance ability was (48.28±10.64) in the intervention group,which was significant higher than that of in the control group (32.04±11.42),t=6.316,P＜0.05.The fall efficacy in the intervention group was (132.03±27.38),which was significant higher than that of in the control group (108.74±25.68),t=8.256,P＜0.05.The rate of fear falling in the intervention group was 26.09％(12/46),which was significant lower than that of in the control group (32.16T％,15/46),x2=6.545,P＜0.05.Conclusion Flow yoga can improve stroke patients' balance ability and reduce fear of falling.

Objective To explore the influence of follow-up by telephone on adherence and quality of life for breast cancer patients with hormonal therapy.Methods Totally 78 breast cancer patients with hormonal therapy were divided into the intervention group (40 cases) and the control group (38 cases).The control group were carried on routine guidance treatment and enjoined regular subsequent visit.The patients in intervention group were carried on the above-mentioned treatment and also receive regular follow-up by telephone.Through the follow-up by telephone we provided guidance for present and will present problems.Adherence for breast cancer patients with hormonal therapy and cancer rehabilitation evaluation system-short form(CARES-SF) were used to investigate the patients' adherence and quality of life six month after the intervention.Then we compared the adherence and quality of life before,six month of the intervention.The changes of adherence and quality of life scores were analyzed by repeated-measure ANOVA.Results The score of quality of life in the intervention group after 6 month of intervention was (25.43 ± 6.04),while in the control group was (40.61 ± 7.73),the difference was significant between the two groups,P＜0.05.The score of medication adherence in the intervention group after 6 month of intervention was (8.57 ± 6.20),while in the control group was (14.12 ± 6.63),the difference was significant between the two groups,P＜0.05.Conclusion Follow-up by telephone can improve adherence and quality of life for breast cancer patients with hormonal therapy.

Hypertension is a leading cause of mortality and morbidity around the world and,prevalence of hypertension is increasing with aging.Hypertension in the elderly is associated with increased occurrence rates of sodium sensitivity,isolated systolic hypertension,and 'white coat effect'.Arterial stiffness and endothelial dysfunction also increase with age.These factors should be considered in selecting antihypertensive therapy.The prime objective of this therapy is to prevent stroke.The fmdings of controlled trials show that there should be no cut-off age for treatment.A holistic program for controlling cardiovascular risks should be fully discussed with the patient,including evaluation to exclude underlying causes of secondary hypertension,and implementation of lifestyle measures.The choice of antihypertensive drug therapy is influenced by concomitant disease and previous medication history,but will typically include a thiazide diuretic as the first-line agent;to this will be added an angiotensin inhibitor and/or a calcium channel blocker.Beta blockers are not generally recommended,in part because they do not combat the effects of increased arterial stiffness.The hypertension-hypoten-sion syndrome requires case-specific management.Drug-resistant hypertension is important to differentiate from faulty compliance with medication.Patients resistant to the third-line drug therapy may benefit from treatment with extended-release isosorbide mononitrate.A trial of spironolactone may also be worthwhile.

The role of nuclear factor kappaB in intestine injury induced by hepatic ischemia reperfusion was investigated. Eighteen male Wistar rats were divided into 3 groups randomly: sham operation group (group A), hepatic ischemia reperfusion group (group B) and hepatic ischemia reperfusion plus pyrrolidine dithiocarbamate (PDTC) group (group C). The rats in group A were only subjected to laparotomy, those in group B underwent partial hepatic ischemia reperfusion (ischemia for 1 h and reperfusion for 2 h) and those in group C underwent the same procedure as that of group B but received PDTC 200 mg/kg i.v. before and after ischemia. After reperfusion, tissues of jejunum and venous blood were obtained for measurement of TNF-alpha, MDA and MPO. The levels of TNF-alpha in jejunum and venous blood, the levels of MPO in jejunum in group B were significantly higher than those in group A and group C (P<0.05). There was no significant different in the levels of MDA between group B and group C. The severity of histological intestinal injury in group B and group C was similar. Hepatic ischemia reperfusion caused intestine injury, NF-kappaB may play an important role in this course and the targeting of upstream components of the inflammatory response, such as NF-kappaB, may have important therapeutic applications.
Intestines/*pathology ; Liver/*blood supply ; Liver/metabolism ; NF-kappa B/*biosynthesis ; Random Allocation ; Rats, Wistar ; Reperfusion Injury/*metabolism

Objective Several previous studies have shown androgens deficiency in men with CHF, and 2 studies on the prognostic significance of serum levels of androgens in CHF patients have yielded conflicting results. The aim of this study was to examine the relationship between serum concentration of testosterone and mortality in men with systolic CHF. Methods A total of 175 elderly (age≥60 years) men with CHF were recruited. Total testosterone (TT) and sex hormone binding globulin (SHBG) were measured, and free serum testosterone (eFT) was calculated. The median follow-up time was 1262 days. Results During follow-up 54 (30.9%) patients died. TT and eFT deficiency was found in 21.7% (38/175) and 27.4% (48/175) patients, respectively. Both TT and eFT were inversely associated with LVEF and NT-proBNP (all P<0.01). Kaplan-Meier curves for patients in low, medium and high tertiles according to TT and eFT level showed significantly different cumulative survival rate (both P<0.01 by log-rank test). However, after adjustment for clinical variables, there were no significant associations between either TT or eFT levels or survival time (OR=0.97, 95% CI, 0.84-1.12, P=0.28; and OR=0.92, 95% CI, 0.82-1.06, P=0.14, respectively). Conclusion Our study showed that although levels of TT and eFT are commonly decreased in elderly patients with systolic CHF and related to disease severity, they are not independent predictors for mortality.

ObjectiveTo evaluate the clinical efficacy,untoward reaction of bruceolic oil emulsion combined GP program in treatment of advanced non-small-cell lung cancer(NSCLC).MethodsOne hundred and thirty-six patients with NSCLC were divided into observation group and control group with 68 cases each by random digits table,the two groups were received GP program,the observation group added bruceolic oil emulsion( 1 time a day).The effective rate and untoward reaction between two groups were compared.ResultsThe objective effective rates of observation group and control group were 32.4％(22/68)and 17.6％( 12/68 ),the subjective effective rates of observation group and control group were 52.9％(36/68 )and 32.4％ (22/68),there were significant differences between two groups(P ＜0.05).There was no significant difference in CD3+,CD4+,CD8+,CD56+ between two groups before treatment (P＞ 0.05 ).CD3+,CD4+,CD8+,CD56+ in observation group were better than those in control group after treatment(0.552 ± 0.072 vs.0.468 ± 0.080,0.368 ± 0.062 vs.0.288 ± 0.061,0.268 ± 0.052 vs.0.212 ± 0.044,0.226 ± 0.044 vs.0.168 ±0.042),there were significant differences between two groups (P ＜ 0.05).There was no statistical difference in Ⅲ+ Ⅳ degree untoward reaction between two groups(P ＞ 0.05).ConclusionBetter therapeutic efficacy and less untoward reaction are expected by combined bruceolic oil emulsion with GP program in treatment of advanced NSCLC.

Objective It is to study the influence of atorvatatin on serum C-reactive protein(CRP)level in acute cer- ebral infarction patients and to analyze its clinical significance.Methods 62 patients with acute cerebral infarction di- agnosed by CT or MRI were chosen and divided into two groups randomly.Both the groups were treated with normal method and the treatment group was given atorvastatin 20mg per day.Serum CRP levels in the two groups were measured by immunnturbidimetry within24h after final diagnosis and at two weeks the level decreased obviously in treatment.Re- slllts Serum CRP levels all increased in the patients.After treatment for two weeks the level decreased obviously in treatment group.The difference was significant compared with control group.Conclusion Atorvastatin can markedly reduce the serum CRP level in acute cerebral infarction patients and has important significance for the pathogenetic condi- tion change and prognosis of cerebral infarction.