1.Effect of early active nursing on muscle strength in patients after major operation in intensive care unit
Chinese Journal of Practical Nursing 2015;(31):2373-2375
Objective To analyze the influence of early active nursing on muscle strength in patients after major operation in intensive care unit(ICU). Methods Of 96 ICU patients after major operation were enrolled in the study, 49 patients were assigned to routine ICU nursing (control group, excluding 1 case), and 47 patients were assigned to early active nursing (intervention group, excluding 2 cases) by random number table method. The health condition, muscle strength between 2 groups were compared. Results Acute and chronic physiology score after intervention was (10.62 ±2.04) points in intervention group, and (12.54±2.28) points in control group, and there was significant difference, t=4.269 5, P<0.01. The score of muscle strength was (56.93±4.32) points in intervention group, and (49.42±5.48) points in control group, and there was significant difference, t=7.307 1, P<0.01. The incidence of ICU-acquired muscle weakness in intervention group (6.67%, 3/45) was significantly lower than that of control group (43.75%,21/48), χ2=16.681 5, P<0.01. Conclusions Early active nursing is of great importance to improve muscle strength and decrease the incidence of ICU-acquired muscle weakness.
2.Study on Quality Criteria for Fufangzhixueling Granules
China Pharmacy 2001;0(08):-
OBJECTIVE:To establish the quality criteria for Fufangzhixueling granules.METHODS:TLC was employed to identify Radix Astragali,Rhizoma cimicifuae and Radix Paeoniae Alba,while the content of AstragalosideⅣin Fufangzhix-ueling granules was deteminde by HPLC.RESULTS:TLC findings of Radix Astragali,Rhizoma cimicifuae and Radix Paeoniae Alba showed the spots of same colors as those developed in the corresponding places of control medical materials.The sample size of AstragalosideⅣshowed a good linear relationship within the range of1.551?g~9.306?g(r=0.9996)with the average recovery of97.98%(RSD=1.77%).CONCLUSION:The method is simple,accurate,stable,reliable and with good repro-ducibility,which can be used for the quality control of Fufangzhixueling granules.
3.Qualitative Identification of Composition in Rongshuanwan by TLC
China Pharmacy 2001;0(10):-
OBJECTIVE:To improve the quality standard of rongshuanwan.METHODS:Danshen root,flos,angelica,Chuanxiong in rongshuanwan were respectively identified qualitatively by TLC.RESULTS:The chromatographic spots of samples showed the same colors with those of control agents.The color spectrum was clear without interference of impurity nearby.CONCLUSION:The established method has high specificity and can better control the quality of this drug.
4.Common breakdowns of medical devices and their maintenance
China Medical Equipment 2009;(8):52-53
With the rapid development in science and technology,more and more advanced medical devices have been used in clinical practice.Consequently,the maintenance and management of the devices has become a task of modern hospitals.In this paper,the author discusses some issues for their maintenance and management.
5.Early tracheal intubation endotracheal suctioning line of dealing with the effect of meconium aspiration observation
Chinese Journal of Postgraduates of Medicine 2009;32(z2):54-55
Objective To investigate the early endotracheal intubation line to attract the effect of meconium aspiration. Methods April 2005 to April 2007 the relevant cases (A group) and April 2007 to April 2009 the related cases ( B group) were compared. Results B group and A group efficacy was superior (P < 0.05). Conclusion Early tracheal intubation attract ideal effect of meconium aspiration, it is worth promoting.
6.Effect of Spleen Aminopeptide Oral Lyophilized Powder on urinary RBP and CRP in children with mycoplasma pneumoniae infection and asthma
Chinese Journal of Biochemical Pharmaceutics 2015;(8):167-169
Objective To investigate effect of Splenic Aminopeptide Oral Lyophilized Powder on urinary retinol-binding protein and CRP in children of mycoplasma pneumonia infection with asthma .Methods 60 cases were randomly divided into 2 groups, 30 cases of control group were given conventional anti-inflammatory treatment, azithromycin.30 patients of Experimental group were treated with Spleen Aminopeptide Oral Lyophilized Powder treatment, two groups were treated for 7 days.30 cases of healthy children were selected, given no any treatment.After treatment, urinary retinol binding protein, blood urea nitrogen, creatinine, cough, wheezing symptom recovery, C-reactive protein, blood and other changes were compared between two groups.ResuIts Two groups of children with urinary retinol binding protein, urea nitrogen, creatinine levels were improved in different degrees, and in experimental group, urinary retinol binding protein, urea nitrogen and creatinine decreased significantly compared with control group (P<0.05).Two groups of children with asthma and wheeze improved in different degrees, and cough wheeze, cough and wheeze recovery time of experimental group had more improvement than those of control group ( P<0.05 ) .Two group of C reactive protein and white blood cell level both improved in different degrees, and the experimental group of C reactive protein and white blood cell levels were significantly lower than those of control group (P<0.05).ConcIusion Spleen Aminopeptide Oral Lyophilized Powder can significantly improve the infection status of children with mycoplasma pneumonia, and relieve cough and wheeze symptoms, lower urinary retinol binding protein and C reactive protein level, improve kidney function damage induced by hypoxia.
7.Nonlinear inverse modeling of sensor based on back-propagation fuzzy logical system
Journal of Pharmaceutical Analysis 2007;19(1):14-17
Objective To correct the nonlinear error of sensor output, a new approach to sensor inverse modeling based on Back-Propagation Fuzzy Logical System (BP FS) is presented. Methods The BP FS is a computationally efficient nonlinear universal approximator, which is capable of implementing complex nonlinear mapping from its input pattern space to the output with fast convergence speed. Results The neuro-fuzzy hybrid system, i.e. BP FS, is then applied to construct nonlinear inverse model of pressure sensor. The experimental results show that the proposed inverse modeling method automatically compensates the associated nonlinear error in pressure estimation, and thus the performance of pressure sensor is significantly improved. Conclusion The proposed method can be widely used in nonlinearity correction of various kinds of sensors to compensate the effects of nonlinearity and temperature on sensor output.
8.Study on Poliomyelitis Eradication Strategy of in Hunan Province
Shumin LI ; Junhua LI ; Duanwen HUANG
Journal of Chinese Physician 2000;0(12):-
Objective Through oral vaccination activity on polio,the epidemiological and virological surveillance of acute flaccid paralysis (AFP) case finds its way to develop, so that the realization of eradication on polio may be verified.Method Various kinds of immunization activities such as regular basic immunization, booster vaccination, intensified vaccination and mopping-up operation were adopted among children of the right age in the whole province. Zero case report and active surveillance on AFP were carried out to those population under 15 who had had consultation in medical unit above county level. Each reported case or found case was treated by individual case investigation, follow-up study and sample collection. All the samples were virus-isolated ad identified by RD, Hep-2 and L20B cells. Result Since 1991, an AFP case surveillance system has been built up. Up to the end of 2000, a total of 1,749 AFP cases had been reported in hunan province, from which 1,404 cases samples were collected, and another 218 cases samples of contacts were also collected. A sum of 7 polio wild virus strains was examined out. Since July 1993, no wild strain has been found (isolated). Conclusion Hunan Province has successfully intervened in the circus (spread) of polio wild virus, and hence realized the goal of polio eradication.
9.Mechanism of Ulinastat’s enhancement for antibiotics' curative effects in sepsis children caused by bacteria
Simin ZHANG ; Jun XU ; Junhua LI
Chinese Journal of Biochemical Pharmaceutics 2014;(2):125-127
Objective To study the mechanism of Ulinastat’s enhancement for antibiotics’curative effects in sepsis Children caused by bacteria. Methods Children with sepsis caused by bacteria were treated with Ulinastat combined with antibiotics (UTI group) and antibiotics only (CON group), The curative effects, GSC scores and APACHEⅡscores in two groups were observed and compared, pre-and post-therapy serum procalcitonin and inlfammatory factors were detected and compared. Results The efifciency rate and GSC score in UTI group were signiifcantly higher than in CON group (P<0.05), but lower in mortality and APACHEⅡscore (P<0.05). hs-CRP, TNF-α, IL-6 and IL-8 of UTI group in one week, two weeks and three weeks post-therapy were signiifcantly lower than in CON group (P<0.05), while IL-10 was higher(P<0.05). Conclusion The Ulinastat can signiifcantly increases antibiotics’curative effects for sepsis Children caused by bacteria though lowering down serum PCT, hs-CRP, TNF-α, IL-6 and IL-8 and increasing IL-10.
10.Clinical investigation of the efficacy and safety of continuous intravenous Diltiazem for patients with refractory angina pectoris
Jianping LI ; Wenhui DING ; Junhua ZHANG
Chinese Journal of Interventional Cardiology 2001;9(1):31-33
Objective To investigate the efficacy of infusion Diltiazem for patients with refractory angina pectoris. Methods 10 patients with refractory angina pectoris received continuous intravenous Diltiazem 40~150 μg/min (2.4~9 mg/h) for 48 hours after cessation of intravenous nitroglycerin and oral β-blokers. Results With the single therapy of Diltiazem, 7 patients (70%) got satisfied results: 5 were free from and 2 were relieved of symptom; With the combination therapy of Diltiazem and intravenous nitroglycerin 60~120 μg/min after failed with Diltiazem alone, 3 (30%) patietns got satisfied results: 1 was free from and 2 were relieved of symptom. There is no severe side effects, including hypotension, bradycardia, cardiac function deterioration. Acute myocardial infarction, death and emergency interventional therapy did not occurred in all the 10 patients during the therapy period. Coronary angiography were performed in 8 patients within 1 week after the patients were stabled, 5 patients received PTCA and stent implantation and 3 patients received CABG. Conclusions Continuous intravenous Diltiazem 40~150 μg/min (2.4~9 mg/h) or combination with intravenous nitroglycerin 60~120 μg/min is an efficient and safe therapy for patients with refractory angina pectoris.