1.CT Features of Invasive Hydatidiform Mole
Hongwei WANG ; Changwei DING ; Junhao YANG
Journal of Practical Radiology 2000;0(12):-
Objective To study the CT features of invasive hydatidiform mole and CT value in clinical application. Methods Thirteen cases of invasive hydatidiform mole proved by clinic and pathology were examined with conventional CT and contrast CT, then the CT features were analysed . Results CT findings of invasive hydatidiform mole included : enlargement of uterus, multiple hypodense cysts of different sizes and isodense soft tissue inside uterus, hypodense cysts inside the myometrium thicken irregularly,the cyst wall and isodense soft tissue enhanced markedly and up to 30~50 HU.Conclusion The CT features of invasive hydatidiform mole are specific and CT is of important value in clinical application.
2.Interleukin-10 promoter single nucleotide polymorphism and acute rejection in renal transplantation: a donor-recipient paired study
Junhao LIANG ; Jiping YANG ; Ju QI
Academic Journal of Second Military Medical University 1985;0(06):-
Objective:To study the influence of 3 single nucleotide polymorphisms (SNP) of IL-10 promoter (-1 082, -819 and -594) on acute rejection after renal transplantation in a donor-recipient paired mode. Methods: Three IL-10 promoter SNPs of 52 donor-recipient pairs were genotyped and phenotyped by PCR using sequence-specific primers (SSP). Recipients were followed up for 1 year after transplantation, and acute rejection episodes were observed. Incidences of rejection were compared against pair patterns and differences were analyzed using Fisher's exact test. Results: No genotype of high producer was found in any donor and recipient in this study. Forty-nine recipients were followed up for over 12 months. Of them, 18 recipients (36.7%) had acute rejection and 7 recipients (14.3%) had multiple rejection(MR). The relationship between donors with intermediate producer and acute rejection and MR tended to be statistically significant (P=0.076, P=0.051).The MR rate increased significantly in the pair of donor intermediate producer/recipient low producer (P=0.036). Conclusion: It is preferable to take donor’s IL-10 SNP into consideration in study of IL-10 SNP and renal transplantation. Donor intermediate producer can increase the risk of acute rejection. The combination of donor intermediate/recipient low producer can increase the risk of MR.
3.A clinical study on relationship between the dysfunctions of the first molars and the temporomandibular disorders
Junhao JIANG ; Ya YANG ; Rui SHU ; Jina LIAN ; Weixi WANG
Chinese Journal of Primary Medicine and Pharmacy 2012;19(7):961-963
ObjectiveTo observe the pathogenic relationship and the mechanisms between the first molars and the temporomandibular disorders(TMD) by getting epidemiology data.MethodsThe oral examinational people during 2007 to 2011 as investigating objects were selected and epidemiological study was carried out with standard clinical diagnostic criteria for dental caries TMD.ResultsThe people with dysfunctional first molars showed that TMD positive rate was 51.48%,and normal molars was 23.47%.The results had significant difference( x2 =54.34,P < 0.01 ).ConclusionThe people with dvsfunction of first molars mav be liable to TMD.
4.Study and practice of clinical pharmacy teaching quality monitoring system
Maosheng YANG ; Xiaofeng LIU ; Junhao JIANG ; Yan LIU ; Qingeng LI
Chinese Journal of Medical Education Research 2011;10(5):529-531
Recently, Clinical pharmacy becomes a new specialty of higher education in China. Therefore, building clinical pharmacy teaching quality monitoring system (CPTQMS) is very important not only for improving the teaching quality but also for training inter-disciplinary talents. We try to discuss the connotation and practice of CPTQMS from the objectives, measures and information system. We hope our work can present valuable suggestions for the construction and improvement of CPTQMS in Chinese higher education.
5.Study on Relationship between Red Blood Cell Distribution Width Changes and Prognosis of Acute ;Myocardial Infarction
Yan LIANG ; Junhao YIN ; Jun GUO ; Yang LI
The Journal of Practical Medicine 2016;32(12):1972-1975
Objective To explore the value of? red blood cell distribution width (RDW) changes in acute myocardial infarction (AMI) prognosis by analysing relationship between red blood cell distribution width, cardiac troponin I (cTnI) and high-sensitivity C-reactive protein. Methods 140 hospitalized patients with AMI were selected from May 2014 to October 2014 and devided into 2 groups. 70 patients without heart failure were AMI1 group and the other 70 patients with heart failure were AMI2 group. 70 cases of healthy persons were selected as control group. RDW was compared between three groups and the relationship between the level of RDW, cTnI and hs-CRP was analyzed. Evaluating value of RDW in predicting heart failure in AMI patients by using univariate logistic regression analysis and ROC curve analysis. Results In the comparison of AMI1 group, AMI2 group and control group, either of RDW, cTnI and hs-CRP showed a trend of increasing (P < 0.01). In the AMI patients , RDW level and cTnI level were positive correlation , and there was no linear correlation between RDW level and hs-CRP level. RDW≥14.55% was the independent risk factors in predicting heart failure in patients with AMI. Conclusion RDW≥14.55% can be an available independent predictor of the prognosis of AMI.
6.Factor analysis of quality guidelines for medical treatment
Junhao GUO ; Caixia YANG ; Wanming FU ; Yuxiu LIU ; Hui CAI
Journal of Medical Postgraduates 2003;0(06):-
Objective: To explore the potential influencing factors of the quality guidelines for medical treatment by factor analysis.Method: We analyzed with the SPSS package 9 quality guidelines for medical treatment in the department of integrated TCM and Western medicine of a hospital,including the out-patient person-time,the number of discharges,the average days of hospitalization,the rate of bed utilization,the frequency of bed rotation,the rate of cure and improvement,the case fatality rate,the coincidence rate of diagnoses at admission and discharge,and the success rate of emergency treatment.Results: Four common factors were extracted,namely,the quantifiable factor,determined by the out-patient person-time,the number of discharges,the average days of hospitalization and the frequency of bed rotation;the treatment factor,determined by the cure and improvement rate and case fatality rate;the diagnostic factor,determined mainly by the rate of bed utilization and the coincidence rate of diagnoses at admission and discharge;and the emergency treatment factor,determined by the success rate of emergency treatment.The cumulative contribution rate of the 4 factors was 85.1%.Conclusion: The amount of medical work,the techniques of treatment,the ability of diagnosis and the efficiency of emergency rescue are the main influencing factors of quality guidelines for medical treatment.
7.Study on clinical internship for clinical pharmacy bachelor bridged to clinical pharmacist training
Wengao JIANG ; Zhu YANG ; Yu YU ; Chunjing ZHAO ; Junhao JIANG ; Yan LIU
Chinese Journal of Medical Education Research 2016;15(5):513-516
Clinical internship is for bachelor students to learn how to integrate theories in textbooks with clinical practice.Clinical pharmacist training is for pharmacists to obtain and enforce the capability of rational use of drugs.These two are at the different stages of clinical pharmacist cultivation mode.They are different in teaching nature,goal and students' background.The necessity of clinical internship bridged to clinical pharmacist training is discussed in this paper and after the convergence,the teaching design of chnical internship program bridged to the training is characterized by basic education which focuses on basic theories,knowledge and skills of clinical medicine and clinical pharmacy relevant to a certain common disease.The optimized internship program will work as a good foundation for students to face the challenges of clinical pharmacist training after graduation from school.
8.A massive transfusion protocol for the abdominal surgical patients with traumatic shock
Junhao LAI ; Chong ZHANG ; Bin HU ; Jun YAN ; Xiaowei FAN ; Liuqing YANG ; Jinhui ZHANG
Chinese Journal of General Surgery 2014;29(9):715-718
Objective To investigate the clinical value of the massive transfusion protocols (MTP) in abdominal surgical patients with traumatic shock.Methods An analysis was made on the clinical data of patients before and after the use of MTP,including the general condition,amount of blood transfusion,transfusion components and ratio,blood and coagulation function test,and blood transfusion related complications and mortality.Results Before implement of MTP,the average RBC transfusion in the first 24 hours was 19.5U,FFBwas 12.6U,and the ratio ofRBC ∶ FFB was 1.55 ∶ 1.After implement of MTP,the average RBC transfusion in the first 24 hours was 17.3 U,and the ratio of RBC:FFB was 1 ∶ 1.There were no significant statistical differences between the two groups about PT,APTT,Hb and PLT on admission.After 24 hours of admission,there was no significant difference in Hb between the two groups,there were significant differences of PT,APTT and PLT.Blood transfusion related complications were 11 (14.9%) in control group and 7 (11.9%) in MTP,group,and the mortality was 9.46% and 6.78% respectively.Conclusions MTP improves blood coagulation function,reduces blood transfusion and enhances survival rate of abdominal surgical patients with traumatic shock.
9.A comparative study on transilluminated powered mini-phlebectomy (TriVexTM) and pointed phlebectomy for the treatment of varicosis of the great saphenous vein of the lower limbs
Xin XU ; Weiguo FU ; Yuqi WANG ; Jue YANG ; Zhenyu SHI ; Bin CHEN ; Junhao JIANG ; Longhua FAN
Chinese Journal of General Surgery 2001;0(09):-
ObjectiveTo compare the therapeutic effects of a new surgical endoscopic technique, the transilluminated powered phlebectomy (TriVex System, Smith+Nephew) and pointed phlebectomy in the treatment of varicosis of the great saphenous vein of the lower limbs. Methods Thirty-nine patients (46 limbs) received TriVex operations under spinal, or epidural anesthesia. The powered vein resector and an irrigated illuminator device-a minimally invasive system was used for varicose vein surgery. During the same period, 41 patients (46 limbs) underwent pointed phlebectomy. Results The average postoperative hospital stay was 4.6 days in patients receiving TriVex, and 8.1 days for pointed phlebectomy. Compared with the pointed phlebectomy, the incision of TriVex procedure was shorter and the number less. Conclusion This new surgical device is easy to operate, minimally invasive, efficacious and time saving with satisfactory results.
10.Comparison of operative risks in the infrarenal aortic artery reconstruction between abdominal aortic aneurysm and aortoiliac occlusive disease
Bin CHEN ; Yuqi WANG ; Weiguo FU ; Xin XU ; Daqiao GUO ; Junhao JIANG ; Jue YANG
Chinese Journal of General Surgery 2000;0(11):-
Objective To compare operative risks of the infrarenal aortic artery reconstruction between abdominal aortic aneurysm (AAA) and aortoiliac occlusive disease (AIOD), and to analyze the causes of the difference. Method Clinical data of 340 cases undergoing aortic artery reconstructions including 222 AAA cases and 118 AIOD cases , were analyzed retrospectively. Results The perioperative mortality was 7.6% and the mortality in AAA group (5.4%) was lower than that in AIOD group (11.9%)(P