ObjectiveTo evaluate the therapeutic effect of encircling constriction of superficial femoral vein in the treatment of primary deep venous insuficiency(PDVI).MethodsFrom Jan.2004 to Jun.2011,187 patients( 196 lower extremities)with primary deep venous insufficiency were treated with encircling constriction of venous wall at the first pair of superficial femoral venous valve pulse superficial varicose stripping.Results The 183 limbs in 176 patients were followed-up from 7 months to 8 years,with a mean period for 63.5 months.Ninety-four point one percent of the patients were followed up (176/187).Clinical symptomatic improvement achieved in 87.4％ ( 160/183 ) of the lower extremities.There was 2.2％ ( 4/183 ) of recurrence of the varicose vein,9.3％ ( 17/183 ) of light edema,8％ ( 2/25 ) of recurrence of ulcer.ConclusionEncircling constriction of superficial femoral vein is an effective method in the treatment of primary deep venous valve insufficiency.

OBJECTIVE:To study the mechanism by which L-arginine regulates hypoxic pulmonary vascular structural remodeling.METHODS:Eighteen Wistar rats were randomly divided into control group,hypoxic group and hypoxic+L-arginine group.Pulmonary artery pressure was measured with right cardiac catheterization.Micro-structure and ultra-structure of pulmonary tissue were observed and collagen I expression was evaluated with immunohistochemistry.RESULTS:Mean pulmonary artery pressure(mPAP) was(2.7?0.3)kPa in hypoxic rats and(2.1?0.1)kPa in control rats(P

OBJECTIVE To study the distribution and drug resistance of nosocomial infection(NI) pathogens.METHODS The NI pathogens collected between Jan 2002 and Dec 2008 were completely surveyed and analyzed.RESULTS Totally,9518 samples were cultured to find NI pathogens,in which 6703 NI pathogens were isolated.In the pathogens,G-pathogens occupied 59.5%,G+ cocci 25.0%,and fungi 15.5%.The rate of ESBLs in E.coli was reached to 47.8%,and that in K.pneumoniae was 29.4%;The first two predominant G+ pathogens were Staphylococcus aureus(11.7%) and Enterococcus(5.7%).The rate of MRSA in S.aureus was 78.2%,and that of VRE in Enterococcus was 2.3%,The pathogens of fungus were mainly Candida albicans(10.2%).CONCLUSIONS The G-NI pathogens are markedly increased year by year and become the first important instead of G+ cocci,meanwhile the multiple drug resistance and ESBLs pathogens are also markedly increased.

OBJECTIVE To explore the incidence rate,pathogen distribution and characteristics of drug resistance of ventilator-associated pneumonia(VAP) patients due to acute lung injury and acute respiratory distress syndrome(ALI/ARDS) after severe injury,and analyze impact factors on VAP.METHODS All 183 cases with ALI/ARDS after severe injury from Jan 2004 to Mar 2008,were admiitted and given mechanic ventilation over 48 hours in our ICU and EICU.RESULTS VAP was found in 98 cases,accounted for 53.56%.Among them,42 were early-onset VAP and the other 56 were late-onset VAP.Altogether 276 pathogens were isolated,and most of them were Pseudomonas aeruginosa,Staphylococci aureus,Klebsiella pneumoniae,Acinetobacter baumannii and Escherichia coli.In 41 cases only one pathogen was isolated,the other 57 cases were with two or above pathogens.The revealed important risk factors were coma,prolonged mechanical ventilation,tracheotomy,antiacid treatment,use of antimicrobial agents and low albumin.CONCLUSIONS The incidence rate of VAP due to ALI/ARDS is high,and most of the isolated pathogens are drug resistant.Mixed infections are found commonly in these cases.

Objective To evaluate endoscopy for the diagnosis of primary gastrointestinal mucosaassociated lymphoid tissue lymphoma (MALT lymphoma) and diffuse large B-cell lymphoma (DLBCL).Methods The clinical pathology,hematological/biochemical studies,and endoscopic data of 98 primary gastrointestinal MALT lymphoma and DLBCL patients from Aug 2010 to May 2017 were analyzed retrospectively.Results 17 patients had higher than normal LDH blood level (＞270 U/L).47 patients were Helicobacter pylori (Hp) positive;Gastrointestinal endoscopic study,including endoscopic mucosal resection (EMR)/endoscopic submucosal dissection (ESD) and endoscopic ultrasonography established diagnosis of MALT lymphoma and DLBCL in 96 out of 98 cases (98％).The endoscopic manifestations of MALT lymphoma and DLBCL were ulcerative,uplift,diffuse and infiltrative,and erosive,with ulcerative type as the dominant one.The follow-up examination showed that the survival ratio (88％) of MALT patients was higher than that of DLBCL(68％),and more patients with lower Ann Arbor stage survived (92％) than those with higher Ann Arbor stage (64％).Conclusion Endoscopic biopsy together with endoscopic ultrasonography makes definite diagnosis of MALT and DLBCL.

Objective:To explore the influence of laparoscopic radical gastrectomy on patients′immune functions, coagulation functions and prognoses.Methods:Fifty-eight patients with gastric cancer who underwent laparoscopic radical gastrectomy (laparoscopic group) and 40 patients with gastric cancer who underwent traditional open surgery (traditional group) in Henan People′s Hospital from May 2016 to May 2018 were selected as the subjects. The immune function and coagulation function were compared between the two groups before and after operation. The prognoses of patients underwent laparoscopic radical gastrectomy and the influencing factors were analyzed.Results:Three days after operation, the CD4 + level and CD4 + /CD8 + ratio in laparoscopic group were (29.78±3.58)% and (1.01±0.18), higher than (27.23±3.47)% and (0.93±0.14) in control group ( P<0.05). Three days after operation, the activated partial thromboplastin time (APTT) in laparoscopic group was (26.55±2.56) seconds, shorter than (27.86±2.73) seconds in traditional group, while the levels of fibrinogen (FIB) and D-dimer were (4.24±0.84) g/L and (377.91±47.19) μg/L, higher than (3.88±0.75) g/L and (330.28±45.11) μg/L in traditional group ( P<0.05). The 5-year survival rate was 77.5% in traditional group and 72.4% in laparoscopic group, without significant difference ( P>0.05). Multivariate analysis showed that lymph node metastasis was the independent risk factor for prognosis of laparoscopic radical gastrectomy ( P<0.05). Conclusions:Laparoscopic radical gastrectomy can effectively reduce postoperative immunosuppression, but affect postoperative coagulation function. Lymph node metastasis is closely related to the prognosis of patient with gastric cancer. The patient′s condition should be comprehensively evaluated before and after operation to determine whether the laparoscopic operation is suitable, for reducing postoperative complications and improving the prognosis.

Objective:To explore the influence of laparoscopic radical gastrectomy on patients′immune functions, coagulation functions and prognoses.Methods:Fifty-eight patients with gastric cancer who underwent laparoscopic radical gastrectomy (laparoscopic group) and 40 patients with gastric cancer who underwent traditional open surgery (traditional group) in Henan People′s Hospital from May 2016 to May 2018 were selected as the subjects. The immune function and coagulation function were compared between the two groups before and after operation. The prognoses of patients underwent laparoscopic radical gastrectomy and the influencing factors were analyzed.Results:Three days after operation, the CD4 + level and CD4 + /CD8 + ratio in laparoscopic group were (29.78±3.58)% and (1.01±0.18), higher than (27.23±3.47)% and (0.93±0.14) in control group ( P<0.05). Three days after operation, the activated partial thromboplastin time (APTT) in laparoscopic group was (26.55±2.56) seconds, shorter than (27.86±2.73) seconds in traditional group, while the levels of fibrinogen (FIB) and D-dimer were (4.24±0.84) g/L and (377.91±47.19) μg/L, higher than (3.88±0.75) g/L and (330.28±45.11) μg/L in traditional group ( P<0.05). The 5-year survival rate was 77.5% in traditional group and 72.4% in laparoscopic group, without significant difference ( P>0.05). Multivariate analysis showed that lymph node metastasis was the independent risk factor for prognosis of laparoscopic radical gastrectomy ( P<0.05). Conclusions:Laparoscopic radical gastrectomy can effectively reduce postoperative immunosuppression, but affect postoperative coagulation function. Lymph node metastasis is closely related to the prognosis of patient with gastric cancer. The patient′s condition should be comprehensively evaluated before and after operation to determine whether the laparoscopic operation is suitable, for reducing postoperative complications and improving the prognosis.

Objective? To explore the level of psychological torsion and anticipatory sorrow in patients with chronic gastroparesis and to analyze the relationship between the two. Methods? Totally 121 patients with chronic gastroparesis admitted in Xinxiang Central Hospital from April 2014 to April 2016 were selected using convenient sampling. The patients' general information was collected. The Psychological Strain Scale and the Anticipatory Sorrow Scale were used to evaluate the psychological torsion and anticipatory sorrow levels in these patients. Pearson correlation analysis and multivariate regression analysis were used to analyze the relationship between psychological torsion and anticipatory sorrow. Results? The patients' psychological torsion scored (268.94±46.14), in which the dimension of anticipatory torsion scored the highest, which was (4.61±0.44). Their anticipatory sorrow scored (35.50±5.75), in which the dimension of physical symptom scored the highest, which was (2.46±0.35). The Pearson correlation analysis showed that the total score and scores of various dimensions of psychological torsion were positively correlatively with the total score and scores of the dimensions of self-consciousness, sorrow and physical symptom of anticipatory sorrow (P＜ 0.05). According to the multivariate linear regression analysis, all the four dimensions of psychological torsion were the influencing factors to anticipatory sorrow. Conclusions? The psychological torsion and anticipatory sorrow stand at a high level in patients with chronic gastroparesis, and the two are positively correlated with each other. Psychological torsion may be used to predict anticipatory sorrow. Nurses should take active interventions to reduce the patients' psychological torsion, thereby improving their ability of mediating anticipatory sorrow.

Objective:To explore the effect of remote gastrointestinal symptom cluster monitoring in home nutrition management of gastric cancer patients.Methods:From January to December 2021, convenience sampling was used to select 139 patients with gastric cancer undergoing adjuvant chemotherapy in the Department of Oncology Surgery and Department of Gastroenterology of Xinxiang Central Hospital as the research subject. According to the random number table method, patients were divided into a control group (69 cases) and an observation group (70 cases) . During the chemotherapy period, the control group received routine nursing, while the observation group implemented remote gastrointestinal symptom cluster monitoring for home nutrition management on the basis of the control group. The nutritional indicators, severity and distress of gastrointestinal symptom clusters, and unplanned hospitalization rates between the two groups were compared.Results:After intervention, the hemoglobin, lymphocyte count, albumin, and prealbumin in the control group were lower than those before intervention, and the Patient-Generated Subjective Global Assessment (PG-SGA) score, severity and distress scores of gastrointestinal symptom clusters were higher than those before intervention, with statistically significant differences ( P<0.05) . After intervention, the hemoglobin, lymphocyte count, albumin, and prealbumin in the observation group were higher than those in the control group, and the PG-SGA score, severity and distress of gastrointestinal symptom clusters were lower than those in the control group, with statistically significant differences ( P<0.05) . The unplanned hospitalization rates of the control group and the observation group during chemotherapy were 23.19% (16/69) and 10.00% (7/70) , respectively, with a statistically significant difference ( P<0.05) . Conclusions:Compared with routine nursing, remote gastrointestinal symptom cluster monitoring for home nutrition management can effectively stabilize the nutritional levels of gastric cancer patients during chemotherapy, alleviate gastrointestinal symptom cluster distress, and reduce unplanned hospitalization rates.