2.Advancement of operations for rectal cancer.
Chinese Journal of Surgery 2010;48(21):1610-1612
3.Pathogenesis of giant cell arteritis.
Zhen-ying GUO ; Jun-zhu XU ; Zhen-jie LIU
Chinese Journal of Pathology 2012;41(9):641-644
Animals
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Aortitis
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pathology
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Biopsy
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Dendritic Cells
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pathology
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Diagnosis, Differential
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Giant Cell Arteritis
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drug therapy
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etiology
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metabolism
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pathology
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Glucocorticoids
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therapeutic use
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Humans
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Interleukin-12
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metabolism
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Oxidative Stress
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Polymyalgia Rheumatica
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pathology
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Temporal Arteries
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pathology
4.Echocardiographic and Electrocardiographic Analysis of Coronary Artery Lesions in Kawasaki Disease
jian-jun, ZHANG ; ai-zhen, ZHANG ; xiu-zhen, HAN
Journal of Applied Clinical Pediatrics 1993;0(03):-
Objective To investigate the diagnostic value of combination of echocardiography with electrocardiography for coronary artery lesions(CAL) in Kawasaki disease(KD).Methods Seventy eight children with KD received echocardiographic and electrocardiographic examination.Seventy eight cases were divided into 3 groups according to the results of echocardiogram.Results CAL was discovered in 45 cases and 32 cases with coronary artery dilation,the other 13 cases with coronary artery aneurysm among them.Abnormal electrocardiogram was found in 16 cases.ratio of abnormal electrocardiogram was higher in CAL group than that in normal coronary artery group(P
5.Expression of factors related to peritoneal metastasis of gastric cancer and its relationship to prognosis
Jun ZHEN ; Xu CHEN ; Zhaoyang HAN
Chinese Journal of General Surgery 2001;0(10):-
Objective To study molecular biology and clinicopathologic characters of peritoneal metastasis of advanced gastric cancer and their relationship to prognosis. Methods Based on the molecular biology and the clinicopathologic characters and prognosis single-factor analysis of relevant factors and risk assessment was made in 193 cases of gastric cancer.Results The younger the patient was with the earlier the time of occurrence of peritoneal metastasis of gastric cancer. There was a high expression of ICAM-1 and MMP-2,but low expression of TIMP-1 and p53 in gastric cancer patients with peritoneal metastasis.Conclusions ICAM-1,MMP-2,TIMP-1 and p53 can well predict the occurrence of metastasis and the prognosis of patients with gastric cancer,and these factors can be used for preoperative assessment of the development of metastasis of gastric cancer.
6.Survey on the prevalence of common chronic diseases in the elderly in rural and urban areas of Shanghai
Maosheng HUANG ; Zhen HONG ; Jun ZENG
Chinese Journal of Geriatrics 2000;0(04):-
Objective To study the prevalence and the distribution of several chronic diseases which affect the life quality and the health of the Shanghai elderly people. Methods Stratified cluster sampling method was used in the survey of the prevalence rate of several common chronic diseases (self reported) in 12 590 residents ≥60 years of age in 22 urban and 14 rural communities in Shanghai. Results The total prevalence rate of several chronic diseases in the elderly is 60 3%, with male being 59 4% and female being 61 9%. The total prevalence rate in the urban elderly was 66 5%, significantly higher than that of the rural elderly(53 9%). In urban areas, female's prevalence was higher than the males. While in rural area no difference between male and female was observed. In urban areas, the prevalence from high to low stood hypertension(33 6%), cataract(18 3%), chronic obstructive pulmonary disease (COPD)(11 9%), coronary heart disease(9 1%), other heart diseases(7 9%), diabetes mellitus(5 9%). In rural areas, the prevalence from high to low stood hypertension (20 9%), COPD(15 2%), cataract(7 0%), deafness(5 7%), other heart diseases(4 3%), osteoideformed or osteoporosis(4 2%). Conclusions The distribution and the status of the chronic diseases in rural areas are significantly different from that of urban areas. We should carry out different strategies according to different conditions for enhancing the health and life quality of the elderly.
7.Evaluation of early composite treatment for cervical spinal cord injury caused by diving injury
Wanxin ZHEN ; Jun SHEN ; Guoyong GAO
Orthopedic Journal of China 2006;0(12):-
[Objective] To evaluate the therapeutic effect of early composite treatment in patients with cervical spinal cord injury(SCI) caused by diving injury.[Method]27 patients of SCI caused by diving injury,including complete SCI in 15 patients and incomplete SCI in 12 patients,were analyzed.Early composite treatment scheme were as follows:(1) systemic treatment: respiratory support and effective circulation volume for maintenance of systolic pressure more than 90mmHg and oxygen saturation more than 90%.(2) Early pharmacological treatment such as methylprednisolone and dexamethasone.(3) Immobilization and reduction of the injured cervical spine by skull traction.(4) Early cervical decompression,reduction,graft and internal fixation.(5) Early hyperbaric oxygen therapy after operation.The stability and fusion of the injured segments and the complications of the hardware were observed on the X-ray film postoperatively.The spinal cord function was evaluated with ASIA grades and sensorymotor scores.[Result]All 27 patients were followed up for 12 to 36 months,with an average of 28 months.No intra-operative and post-operative complications,the incision healed well.The injured segments were stable and all bone grafts acquired fusion in 3 months,no plates or screws broken or loosen.The neurological recovery were detected in 13 patients.The neurological recovery rate was 20% in complete SCI,83.3% in incomplete SCI,48.1% in the total.The ASIA grades of the sensory and motor scores could hardly be improved postoperatively in complete spinal cord injury while in incomplete spinal cord injury the ASIA grades and sensorymotor scores increased significantly.[Conclusion]Early composite treatment of cervical spinal cord injury caused by diving injury can significantly improve neurological function of the cervical spinalcord injury patients.
8.Expression of survivin gene in hematological tumour cell strains
Jun XUE ; Maofang LIN ; Zhen CAI
Chinese Journal of Pathophysiology 1986;0(02):-
Dami) existed. The transcriptional levels of survivin gene in K562/ADR cell strain was 1.6-fold higher than that in K562 cell strain,but wasn't detected in peripheral blood mononuclear cells(PBMNCs).All-trans retinoic acid significantly decreased survivin mRNA expression levels. CONCLUSION: These data suggest that the survivin gene might be a potential therapeutics target due to the role in anti-apoptosis and drug resistance.
9.Serum levels and clinical significance of IL in patients with delayed encephalopathy after acute carbon monoxide poisoning.
Long ZHEN ; Ren-jun GU ; Ping ZHANG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2008;26(9):561-562
Adult
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Aged
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Aged, 80 and over
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Carbon Monoxide Poisoning
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complications
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Female
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Humans
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Interleukins
;
blood
;
Male
;
Middle Aged
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Neurotoxicity Syndromes
;
blood
;
etiology