Objective To evaluate the influence of tirofiban to percutaneous coronary intervention.Methods 66 elderly patients with coronary artery disease were treated,they were divided into the study group of 33 cases and the control group of 33 cases.The control group was treated with simple percutaneous coronary intervention treatment, the study group was treated with percutaneous coronary intervention combined with tirofiban.The changes of LVEF, cTnT,and TIMI,symptoms in the treatmeat and the symptoms after 2 years were observed and compared.Results After treatment,the patients'platelet count was to the basic line,the difference was not statistically significant(t =0.353 3,P >0.05).The cTnT,LVEF levels of the study group were significantly better than the control group,the differences were statistically significant(t =5.138 1,8.658 1,all P <0.05).After treatment,the incidence rate of TIM in both two groups were improved compared with before treatment.After treatment,the incidence rate of TIMI 3 of the study group(93.9%) was significantly higher than the control group(69.7%),the difference was statistically significant(χ2 =6.518 5,P <0.05).After treatment,the remission rate of angina of the study group(87.9%) was significantly higher than the control group(60.6%),the difference was statistically significant (χ2 =6.417 8,P <0.05).After 2 years of follow -up , the remission rate of angina and recurrent angina in the study group were significantly better than the control group,the differences were statistically significant (χ2 =5.076 9,3.995 2,all P <0.05).Conclusion The efficacy of percutaneous coronary intervention combined with tirofiban is significant,the prognosis is good,has higher remission,it is suitable for long -term clinical application.

Objective To analyse effects of high dietary fiber intervention on gestational diabetes mellitus(GDM ) .Methods 148 GDM hospitalized patients were selected as the research objects and they were divided into two groups randomly .72 patients in the control group controlled their diets by themselves ,while the 76 patients in the treatment group accepted the high dietary fiber inter-vention from the nutritionists based on their different conditions .The fasting plasma glucose(FPG) ,2-hour postprandial blood glu-cose(2hPG) ,hemoglobin A1c(HbA1c) ,triglyceride(TG)and total cholesterol(TC)were recorded in dietary therapy and the out-comes of pregnancy were followed up .Results Under diet control for 12 weeks ,The levels of FPG ,2hPG ,HbA1c ,TG and TC of twe groups reduced obviously(P<0 .05) .The effects of the treatment group was better than the control group(P<0 .05) .The av-erage weight of the patients′infants in the control group was(3 .82 ± 0 .72)kg ,while that in the treatment group was(3 .22 ± 0 .63) kg ,and the difference had statistical significance(P<0 .01) .Also ,the probability of the infant and mom complications in treatment group was obviously lower than that in the control group(P<0 .01) .Conclusion High dietary fiber intervention has great curative effects on patients with GDM ,and the reasonable dietary therapy can reduce the probability of complications .

Objective To explore the correlation between the joint detection of cholinesterase(CHE),alpha-L-fucosidase(AFU) and alpha-fetoprotein(AFP)and primary hepatic cancer(PHC).Methods 56 cases of patients with PHC(PHC group),52 cases of patients with liver cirrhosis(LC group)and 60 cases of healthy individuals(control group)were enrolled in this study,and serum levels of CHE,AFU and AFP were detected and statistically analysed.Results Serum levels of CHE in patients with PHC were negatively correlated with levels of AFU and AFP(correlation coefficient was -0.889 and -0.797 respectively,P <0.05),the ser-um levels of CHE in patients with LC were also negatively correlated with levels of AFU and AFP (correlation coefficient was-0.598 and -0.653 respectively,P <0.05).The positive rates of joint detection of CHE,AFU and AFP in PHC group and LC group were higher than that in the control group,had statistically significant differences(P <0.05 ).Conclusion CHE,AFU and AFP are sensitive indicators of liver lesions,and the joint detection could provide reference value for diagnosis and monitoring pro-gression of PHC.