2.Inappropriate secretion of thyroid stimulating hormone in a Filipino patient with a pituitary macroadenoma.
Bunoy Lermah S ; Co Juan Maria Ibarra O
Journal of the ASEAN Federation of Endocrine Societies 2012;27(1):114-118
Pituitary tumors producing thyrotropin are very rare. We report a case of a 38-year-old, male admitted for seizure, preceded by 1 week history of generalized weakness, fatigue, anorexia, nausea and vomiting, with a 5 year history of recurrent headache followed by blurring of vision, who was found to have persistently elevated serum free thyroid hormones and non-suppressed thyroid stimulating hormone (TSH) levels, with tumor residual after craniotomy with excision of the pituitary macroadenoma. To our knowledge, this is the first reported case of TSH-producing adenoma in the Philippines.
Male ; Adenoma ; Anorexia ; Craniotomy ; Headache ; Nausea ; Philippines ; Pituitary Neoplasms ; Seizures ; Thyroid Hormones ; Thyrotropin ; Vomiting
3.Pattern of weight loss after successful enucleation of an insulin-producing pancreatic neuroendocrine tumor
Mark Anthony Santiago Sandoval ; Tom Edward Ngo Lo ; A&rsquo ; Ericson Berberabe ; Mark Anthony De Lusong ; Juan Maria Ibarra Co
Journal of the ASEAN Federation of Endocrine Societies 2015;30(2):160-163
We report the case of a patient with hypoglycemic symptoms and weight gain. Biochemical investigations revealed endogenous hyperinsulinemic hypoglycemia. A CT scan and MRI of the abdomen were initially not successful in localizing a pancreatic mass. However, an endoscopic ultrasound was able to demonstrate a pancreatic head mass. Enucleation of the mass resulted in clinical and biochemical improvement. This report also demonstrates the pattern of weight loss after surgery, showing an initial phase of gradual weight loss followed by a rapid loss of weight. This pattern of weight loss after successful removal of an insulin-producing pancreatic neuroendocrine tumor is a novel addition to the existing knowledge we have about this condition.
Hypoglycemia
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Insulinoma
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Weight Loss