Humans ; Multiple Myeloma ; complications ; Neuritis ; etiology ; prevention & control ; therapy ; Renal Insufficiency ; etiology ; prevention & control ; therapy

Chromosome abnormality has recently been recognized as an important cause of congenital heart diseases(CHD).The tiny fragment deformity of the chromosome may lead to many abnormal genes expression.Recent studies have disclosed that CHD is a part of syndrome attributed to chromosome abnormality.This article reviews chromosome abnormality caused by trisomy chromosome,chromosome deletions,Tuner syndrome and Kleinfelte's syndrome as well as incidence,type,mechanism and prognosis of its complicated CHD.

Necrotizing enterocolitis is an acute gastrointestinal disease in infants.Recent studies have reported that approximately 25％ to 35％ infants receiving packed red blood cell transfusions develop transfusionrelated necrotizing enterocolitis.The pathogenesis of transfusion-related necrotizing enterocolitis is not clear.This article reviews previous researches and current theoretical perspectives of transfusion-related necrotizing enterocolitts.

The B-D test is one of the important parameters for examining sterilizing effect of the pulsation vacuum pressure sterilizer,which has to be performed before application to sterilization.So before high pressure antisepsis,we must carry on the B-D test of the pulsation vacuum pressure steam sterilizer.With the causes analyzed,some solutions are put forward to enhance the reliability of B-D test failure.

Objective To study the IE and pp67 mRNA expressions in infants infected human cytomegalovirus (HCMV) after ganciclovir treatment. Methods The values of total bilirubin (TBIL), direct bilirubin (DBIL), alanine amino-transferase (ALT) and alkaline phosphatase (ALP) were detected in patients with HCMV before treatment, 2 weeks and 4 weeks after treatment. The HCMV-DNA was detected by quantitative PCR. The expression levels of IE mRNA and pp 67 mRNA were detected by real-time fluorescent quantitative PCR. Results HCMV DNA stopped copying and the infected in-fants were cured following the traditional criterion, however, RNA expression was still tested in part of these infants. Conclusion It should be identified for mRNA expression when HCMV-DNA copies were hardly identified in these infants to prevent from relapse.

Objective To analyze the risk factors of coronary heart disease(CHD) by health examination in Huizhou.Methods A total of 85 patients withCHD,were chosen from 970 health check-up subjects as research cases.The roles of 6 risk factors of CHD were analyzed.Results 970 examination,amomg the CHD group were 85 cases(8.8% ),non-CHD group( control group)338 cases(34.8% ),normal healthy individuals 547 cases(56.4% ) respectively;The age of 60-year-old,70-year-old were significantly higher than 50 years in CHD(X2=6.78,X2=7.02,P＜0.01 );The prevalence of obesity 、smoking、over-drinking 、hypertension and dyslipidemia in CHD group were higher than that in control group( t = 2.71,t = 2.803,t = 2.875,t = 2.841,t = 2.901,all P ＜ 0.01 );The index of crowding index ≥ 1 for 92.8%,≥ 3% for 41.2% in 85 cases with CHD;Analysis showed that coronary heart disease andTG ( r = 0.28,P ＜ 0.001 ),TC ( r = 0.23,P ＜ 0.001 ),SBP( r= 0.14,P = 0.011 ) were significantly positively correlated.Conclusions Dyslipidemia、hypertension、obesity 、smoking、over-drinking are the remarkable risk factors of CHD in Hui Zhou.

The survival of extremely low birth weight infants has increased significantly due to improvement in both scientific knowledge and technology.Lung protective ventilatory strategies have been used for these infants in attempts to decrease lung injury severity and the incidence of bronchopulmonary dysplasia.The modalities of respiratory support will depend on the status of birth.It is important to apply these techniques correctly to achieve adequate gas exchange and avoid ventilatory injury.Non-invasive ventilatory support shows valuable as an initial intervention after birth and is an effective alternative to endotracheal intubation or mechanical ventilatory treatment.

As most of medical school has been incorporating with comprehensive university,it is of great importance for university leaders and managers to make out how to take full advantage of the opportunity for incorporating with university and make full use of medical education resource to improve the benefit of capital operation.

Despite survival of extremely preterm infants has increased over recent years,bronchopul-monary dysplasia( BPD) remains both a major cause of mortality and one of the most common complications with implications into adulthood on respiratory and neurologic health. Steroids have a clear beneficial effect on BPD,but there is much debate surrounding the use of corticosteroids on the prevention and treatment of BPD. Careful consideration of the available data along with the clinical characteristics of the individual infant is required before being introduced into therapy.

Marine organism is important source of antineoplastic active substance,sponge is the secondly larger amount of organism source besides coral in the ocean. In recent decade, several high antineoplastic active substances with novel structure are abstracted and identified from different kinds of sponges. These discovers reveal bright prospect of research and development. This article summarized antineoplastic active sponge abstracts and their synthesis derivative which still in the clinical trials,their origins and the research development of their chemical composition and pharmacological action.