Humans ; Multiple Myeloma ; complications ; Neuritis ; etiology ; prevention & control ; therapy ; Renal Insufficiency ; etiology ; prevention & control ; therapy

Necrotizing enterocolitis is an acute gastrointestinal disease in infants.Recent studies have reported that approximately 25％ to 35％ infants receiving packed red blood cell transfusions develop transfusionrelated necrotizing enterocolitis.The pathogenesis of transfusion-related necrotizing enterocolitis is not clear.This article reviews previous researches and current theoretical perspectives of transfusion-related necrotizing enterocolitts.

The B-D test is one of the important parameters for examining sterilizing effect of the pulsation vacuum pressure sterilizer,which has to be performed before application to sterilization.So before high pressure antisepsis,we must carry on the B-D test of the pulsation vacuum pressure steam sterilizer.With the causes analyzed,some solutions are put forward to enhance the reliability of B-D test failure.

Objective To analyze the risk factors of coronary heart disease(CHD) by health examination in Huizhou.Methods A total of 85 patients withCHD,were chosen from 970 health check-up subjects as research cases.The roles of 6 risk factors of CHD were analyzed.Results 970 examination,amomg the CHD group were 85 cases(8.8% ),non-CHD group( control group)338 cases(34.8% ),normal healthy individuals 547 cases(56.4% ) respectively;The age of 60-year-old,70-year-old were significantly higher than 50 years in CHD(X2=6.78,X2=7.02,P＜0.01 );The prevalence of obesity 、smoking、over-drinking 、hypertension and dyslipidemia in CHD group were higher than that in control group( t = 2.71,t = 2.803,t = 2.875,t = 2.841,t = 2.901,all P ＜ 0.01 );The index of crowding index ≥ 1 for 92.8%,≥ 3% for 41.2% in 85 cases with CHD;Analysis showed that coronary heart disease andTG ( r = 0.28,P ＜ 0.001 ),TC ( r = 0.23,P ＜ 0.001 ),SBP( r= 0.14,P = 0.011 ) were significantly positively correlated.Conclusions Dyslipidemia、hypertension、obesity 、smoking、over-drinking are the remarkable risk factors of CHD in Hui Zhou.

The survival of extremely low birth weight infants has increased significantly due to improvement in both scientific knowledge and technology.Lung protective ventilatory strategies have been used for these infants in attempts to decrease lung injury severity and the incidence of bronchopulmonary dysplasia.The modalities of respiratory support will depend on the status of birth.It is important to apply these techniques correctly to achieve adequate gas exchange and avoid ventilatory injury.Non-invasive ventilatory support shows valuable as an initial intervention after birth and is an effective alternative to endotracheal intubation or mechanical ventilatory treatment.

Chromosome abnormality has recently been recognized as an important cause of congenital heart diseases(CHD).The tiny fragment deformity of the chromosome may lead to many abnormal genes expression.Recent studies have disclosed that CHD is a part of syndrome attributed to chromosome abnormality.This article reviews chromosome abnormality caused by trisomy chromosome,chromosome deletions,Tuner syndrome and Kleinfelte's syndrome as well as incidence,type,mechanism and prognosis of its complicated CHD.

Despite survival of extremely preterm infants has increased over recent years,bronchopul-monary dysplasia( BPD) remains both a major cause of mortality and one of the most common complications with implications into adulthood on respiratory and neurologic health. Steroids have a clear beneficial effect on BPD,but there is much debate surrounding the use of corticosteroids on the prevention and treatment of BPD. Careful consideration of the available data along with the clinical characteristics of the individual infant is required before being introduced into therapy.

Objective To study the IE and pp67 mRNA expressions in infants infected human cytomegalovirus (HCMV) after ganciclovir treatment. Methods The values of total bilirubin (TBIL), direct bilirubin (DBIL), alanine amino-transferase (ALT) and alkaline phosphatase (ALP) were detected in patients with HCMV before treatment, 2 weeks and 4 weeks after treatment. The HCMV-DNA was detected by quantitative PCR. The expression levels of IE mRNA and pp 67 mRNA were detected by real-time fluorescent quantitative PCR. Results HCMV DNA stopped copying and the infected in-fants were cured following the traditional criterion, however, RNA expression was still tested in part of these infants. Conclusion It should be identified for mRNA expression when HCMV-DNA copies were hardly identified in these infants to prevent from relapse.

As most of medical school has been incorporating with comprehensive university,it is of great importance for university leaders and managers to make out how to take full advantage of the opportunity for incorporating with university and make full use of medical education resource to improve the benefit of capital operation.

Objective To analyze the pattern of antibiotic resistance in 1 073 strains of Pseudomonas aeruginosa in People's Hospital of Xinjiang Autonomous Region during 2003-2007. Methods Automated microbe analyzer (VITEK32) was used to analyze antibiotic susceptibility by means of GNS drug sensitivity card and Kirty-Bauer method. Results In recent five years, 1 073 strains of P. aeruginosa were isolated from respiratory specimens, most of which were from ICU, respiratory ICU and surgery ICU (57.8%). Among the 16 antibiotics tested, these strains showed the lowest resistance (17.0%) to cefoperazone-sulbactam, followed by meropenem (18.5%), amikacin (19.6%), imipenem (24.2%), cefepime (25.7%), piperacillin-tazobactam (35.7%) and ceftazidime (36.7%). Although the resistance to cefoperazone-sulbactam and ceftazidime was relatively lower, the prevalence of intermediate strains was relatively higher, 15.2% and 12.5% respectively. Conclusions The antibiotic resistance surveillance Results of five consecutive years indicate that P. aeruginosa was one of the most common pathogens in this hospital associated with serious issue of antibiotic resistance.