Objective To analyze psychological changes of patients underwent the hematopoietic stem cell collection and explore the importance of health education in order to support the proceeding of collection smoothly.Methods A total of 50 patients underwent the hematopoietic stem cell collection were divided into two groups:study group(n = 25)and control group(n =25).The control group performed the pure pharmacotherapy while the study group performed health education based on the pharmacotherapy.Results Indicators including the coping style of discomfort symptoms and the knowledge of health education in the study group were better than that in the control group.Conclusions Psychological status of patients plays an important role during collecting proceeding of hematopoietic stem cell.The health education may raise patient' s related knowledge,thus assisting the successful collection.

This paper described the results of the optimal method for preparation and extraction of lectin from Phaeoporus obliquus(Pers ex Fr).(J.Schroet).We determined the optimal buffer solution using the ag-glutination test with 2% hare blood cells.The optimal extraction process included the following parameters that were conformed by optimization analysis: material-water ratio,extraction time,concentration of sodium chloride and the pH value.The results are that the agglutination indexes of POL using TBS and PBS extrac-tion buffer were 64 and 16,respectively.The optimal extraction process is that,the material-water ratio was 1:50,the extraction time was 20 h,while the concentration of sodium chloride was 0 mol/L and pH was 8.0.The agglutinability of POL was 256 examined by this method.The optimized extraction process is stable and practicable,which may supply some basis for the application of the lectin from Phaeoporus obliquus in immunoregulation.

Objective To explore the impact of psychological intervention on the mental state of related donors for allogeneic hematopoietic stem-cell transplantation(HSCT). Methods 64 donors for HSCT were randomly divided into intervention and control groups (32 cases for each group). Routine preoperative health education was given to the donors in the control group and psychological intervention was adopted in the intervention group on the basis of routine health education. Zung self-rating depression scale (SDS) and self-rating anxiety scale (SAS)were used to mark the scores of the mental state of donors in both groups and heart rate, blood pressure of the donors were recorded and analyzed before and after intervention. Results Compared with those before intervention, there were no statistically significant differences in blood pressure and heart rate of the donors in the intervention group (P ＞ 0. 05); the differences were statistically significant in the comparison of blood pressure and heart rate of the donors between the two groups (P ＜ 0. 05). The scores of depression and anxiety decreased compared with those before intervention in the intervention group (P ＜ 0. 05), and the differences in the comparison of the scores were statistically significant between the two groups (P ＜ 0. 05). Conclusions Psychological intervention is the key to reduce anxiety and depression and stabilize blood pressure and heart rate of the related donors for allogeneic hematopoietic stem-cell transplantation.

OBJECTIVETo investigate the effect of compound Danshen Dripping Pill (CDDP) on peripheral arterial intima-media thickness (IMT) in patients newly diagnosed as type 2 diabetes mellitus.

METHODSOne hundred and eight patients were equally randomized into 3 groups, in addition to the basic hypoglycemic, hypotensive and lipid-regulation treatment, they were administered orally with aspirin (0.1 g, once daily), vitamin E (0.1 g, twice daily) and CDDP (10 pills, thrice daily) for 18 months, respectively. The conventional cardiovascular risk factors, such as hyperglycemia, lipids profile, and homeostasis model assessment of insulin resistance (HOMA-IR) as well as ultrasound measurement of peripheral arterial IMT before and after treatment were compared.

RESULTSIn the group treated with CDDP after treatment, the levels of HbA1c, serum total cholesterol and low density lipoprotein cholesterol (LDL-C) were significantly lower (all P<0.01), HOMA-IR was higher than those in the other two groups; while IMTs of carotid, iliac and femoral arteries were insignificantly different among them (P>0.05); however, the increment of carotid IMT in the CDDP treated group was less than that in the aspirin treated group (P<0.05), and that of femoral IMT was less than both the aspirin and vitamin E treated groups (P<0.05).

CONCLUSIONFor the patients with newly diagnosed type 2 diabetes, additional administration of CDDP to the conventional treatment could exert beneficial effects on blood glucose controling, and lipid profile improvement and delay of arterial intima-media proliferation.

Adult ; Aged ; Aspirin ; therapeutic use ; Blood Glucose ; analysis ; Carotid Intima-Media Thickness ; Cholesterol ; blood ; Diabetes Mellitus, Type 2 ; drug therapy ; pathology ; Diabetic Angiopathies ; prevention & control ; Drugs, Chinese Herbal ; therapeutic use ; Female ; Humans ; Insulin Resistance ; Male ; Middle Aged ; Phenanthrolines ; therapeutic use ; Phytotherapy ; Salvia miltiorrhiza ; chemistry ; Vitamin E ; therapeutic use

"Tinglizi", the ripe seed of Descurainia sophia and Lepidium apetalum, is a member of Brassicaceae (Cruciferae). Traditionally, the former is called "Nantinglizi" (Descurainiae Semen) while the latter is called "Beitinglizi" (Lepidii Semen). In the theory of traditional Chinese medicine, it has the power to purge lung-fire, relieve dyspnea, promote diuresis and reduce edema, and it is mainly indicated in a case with phlegm-fluid accumulation, cough with excessive sputum, dyspnea with being unable to lie, and general swelling. In view of its wide-spread application in clinic, a comprehensive review of Lepidii Semen and Descurainiae Semen was conducted from the following aspects: herbalogical study, variety identification, historical evolution of processing, chemical constituents, pharmacological effects, quantitative determination and toxicity which could provide reference for further research and development of "Tinglizi".
Brassicaceae ; chemistry ; Diuresis ; drug effects ; Drugs, Chinese Herbal ; adverse effects ; chemistry ; isolation & purification ; pharmacology ; Dyspnea ; drug therapy ; Edema ; drug therapy ; Humans ; Lepidium ; chemistry ; Lung ; drug effects ; Medicine, Chinese Traditional ; Molecular Structure ; Plant Components, Aerial ; chemistry ; Plants, Medicinal ; Seeds ; chemistry

OBJECTIVETo discriminate Descurainiae Semen and Pantagirus Semen.

METHODA high-performance liquid chromatographic method was developed to establish the fingerprint of Descurainiae Semen, and hierarchical cluster analysis (HCA) and partial least squares discriminant analysis (PLS-DA) were applied to study HPLC fingerprinting and chemical recognition.

RESULTThere exists large difference of chromatographic peaks and its relative peak area of HPLC fingerprints between Descurainiae Semen and Pantagirus Semen, and after conducting statistical analysis, the result demonstrated that all samples were classified into three categories: Descurainiae Semen, Pantagirus Semen and their mixtures.

CONCLUSIONThe developed HPLC fingerprint combined with chemometrics can be utilized to discriminate between Descurainiae Semen and Pantagirus Semen, which was quick, simple, accurate and reliable an can provide the basis for the characterization and quality assess of Descurainiae Semen and Pantagirus Semen.

Brassicaceae ; chemistry ; Chromatography, High Pressure Liquid ; methods ; Cluster Analysis ; Least-Squares Analysis ; Plants, Medicinal ; chemistry

Objective To investigate untreated leukemia patients' compliance with chemotherapy and analyze the related factors , in order to take effective intervention measures to improve the patients' Chemotherapy compliance, as well as provide high quality services information to clinical nurses. Methods 100 eases of untreated leukemia patients were randomly divided into intervention group and control group, 50 cases were included in each group. In the intervention group, patients received individual nursing intervention, the nurses in this group harbered good communication skills, more comprehensive knowledge, and were all senior members, while those in the control group received routine care. Results The patients' chemotherapy compliance in intervention group was higher than that in control group, and the difference between the two groups was significant (P < 0.01). Conclusions Implementing the comprehensive and effective individualized interventions to untreated leukemia patients and their families can improve their compliance with chemotherapy, thus ensuring the effective medical care.

This study was aimed to investigate the clinic significance of helicobacter pylori (HP) in children with idiopathic thrombocytopenic purpura (ITP). The infection of HP in 92 ITP children was determined by (13) C-Urea Breath Test, the same test was also performed on 66 healthy children. The 68 children infected with HP were randomly divided into 2 groups: single drug group treated only with corticosteroid and; combined drug group treated with corticosteroid and anti-helicobacter pylori treatment. The results showed that 68 patients infected with HP were found in 92 ITP children (74.7%), 26 patients infected with HP were observed in 66 healthy children (39.4%), which was lower than that in ITP children (74.7%, P < 0.05). After anti-helicobacter pylori therapy, the total effective rate and cure rate of ITP patients increased respectively from 73.5% to 94.1%, and the total recurrence rate (17.0%) was much lower than single drug group (47.1%, P < 0.05). Otherwise, after therapy the platelet count in both two groups increased continuously, and at the same time point, the platelet count in anti-helicobacter pylori group was higher than that in the single drug group (P < 0.05). It is concluded that the ITP children have a higher infection rate of HP, which may be involved in the pathogenesis of ITP. Anti-helicobacter pylori therapy would help to improve the therapeutic efficacy and reduce the recurrence of ITP children.
Adrenal Cortex Hormones ; therapeutic use ; Breath Tests ; Case-Control Studies ; Child ; Female ; Helicobacter Infections ; complications ; drug therapy ; Helicobacter pylori ; Humans ; Male ; Platelet Count ; Purpura, Thrombocytopenic, Idiopathic ; complications ; microbiology ; Treatment Outcome

Objective To investigate the condition of social support of leukemia patients, discuss the influence of social support on their life quality, and provide reference point for nursing of leukemia patients. Methods Perform SSRS questionnaire and WHO QoL-BREF on 50 leukemia patients during symptomatic relief period, another 50 healthy cases were as control group. The results were analyzed with mathematical statistics test. Results The relation between social support and life quality of leukemia patients is positive. Conclusions The integrated clinical, Familial and social support system is very important for improving the life quality of leukemia patients. Clinical workers, Family members and the whole society should be encouraged to provide more care to leukemia patients, and to improve both of their psychological and physiological health condition.

undergo the peripheral blood stem cell collection have anxiety of different degrees. The effective nursing intervention measures can obviously improve the patients' anxiety state.