There is strong evidence that paranoia can be an existing trait in the general population as a continuous dimension ranging from minimal levels to paranoid personality traits, and that at its maximum expression could take the form of disabling psychotic disorders such as delusional disorder or schizophrenia however, and according to Caviedes, GEC and Yonfá, EDA. Here are studies in which the existence of comorbidity between paranoid, borderline, antisocial and histrionic personality and problematic alcohol consumption is mentioned which in psychopathological terminology is called dual pathology (comorbidity of mental disorder and toxic consumption).

A case of sexual assault and murder of a minor perpetrated by a subject who kept the body hidden for more than a year in his own home is illustrated, with waste of all kinds and configuring a pathological personality profile of Syndrome of Diogenes.

One of the illegal-criminological phenomena that have had the greatest impact on society is the perpetration of sexual abuse and/or assault in the ecclesiastical sphere. The media and public’s knowledge of this type of criminal act causes an important social repercussion of collective repulsion Tiffon, et al. In sexual terms and within the clerical and religious sphere, the priest does not repress or is prohibited from his sexuality; rather, he sublimates it by understanding that he must have sufficient capacity and self-control to sacrifice his sexuality to channel it to a higher good. In fact, there are very sexually promiscuous people who are unbalanced and celibate people who are balanced Echeburúa

BACKGROUND: Sclerostin inhibits osteoblast functions, differentiations, and survival rates. As an endogenous inhibitor of the Wnt/beta-catenin pathway, the sclerostin should be related to decreased bone masses, although several studies indicate opposite results. In addition, it may be related to insulin resistances and carbohydrate metabolisms, a relation shared with other markers of bone metabolisms, such as osteocalcin. Hepatitis C virus (HCV) infected patients may present osteoporosis, and frequently show liver steatosis, which is a consequence of insulin resistance. The behaviour of sclerostin in these patients is yet unknown. The aim of this work is to analyse the relationships between serum sclerostin and osteocalcin levels and bone mineral density (BMD), liver functions, the intensity of liver steatosis and biochemical markers of bone homeostasis and insulin resistance in HCV-infected patients. METHODS: Forty HCV patients with 20 years of age and gender-matching controls were included in this study and underwent bone densitometry. Serum sclerostin, osteocalcin, collagen telopeptide, adiponectin, leptin, insulin, resistin, tumor necrosis factor (TNF)-alpha, and interleukin (IL)-6 were determined. Liver fat was histomorphometrically assessed. RESULTS: Sclerostin levels were slightly higher in patients than in controls, and were directly related to BMD at different parts of the skeleton, also to the serum telopeptide, and to the liver steatosis and TNF-alpha. On the contrary, osteocalcin showed a significant direct relationship with serum adiponectin, and an inverse one with IL-6. CONCLUSIONS: Serum sclerostin levels were within the normal range in HCV patients, and correlated directly with BMD and serum telopeptide. In addition, the relationships of sclerostin and osteocalcin with variables associated with insulin resistance suggested the role of bones for intermediary metabolisms.
Adiponectin ; Biomarkers ; Bone Density ; Collagen ; Densitometry ; Fatty Liver ; Hepacivirus* ; Hepatitis C* ; Hepatitis* ; Homeostasis ; Humans ; Insulin ; Insulin Resistance ; Interleukin-6 ; Interleukins ; Leptin ; Liver ; Osteoblasts ; Osteocalcin ; Osteoporosis ; Reference Values ; Resistin ; Skeleton ; Survival Rate ; Tumor Necrosis Factor-alpha