1.Clinical practice guidelines on leptospirosis in children 2019
Maria Anna P. Bañ ; ez, M.D ; Melba V. Marasigan, M.D. ; Ma. Liza Antoinette M. Gonzales, M.D., MSc ; Grace Devota G. Go, M.D. ; Fatima I. Gimenez, M.D. ; Mary Antonette C. Madrid, M.D. ; John Andrew T. Camposano, M.D. ; Jennifer M. Nailes, M.D., MSPH ; Ma. Lucila M. Perez, M.D., MSc
Pediatric Infectious Disease Society of the Philippines Journal 2023;24(1):5-69
Executive Summary
Leptospirosis is a disease prevalent mostly in tropical and subtropical countries. Its potential to be a concerning
problem emerges with the onset of the rainy season, as flooding and heavy rainfall facilitate disease epidemics. Among
those at risk of contracting the disease are field workers, veterinarians, sewer workers, military personnel and those
who swim or wade in contaminated waters.
In the absence of an existing evidence-based guideline for the pediatric age group, this first edition hopes to
standardize approach to diagnosis, antibiotic management, and prevention of leptospirosis. The intended users are
primary care physicians, family medicine physicians, pediatricians, and other healthcare workers involved in the
management of leptospirosis in children.
Ten priority questions were identified by a group of experts composed of an oversight committee, a guideline
writing panel, and a technical review committee. The GRADE methodology was used to determine the quality of
evidence of each recommendation. The draft recommendations (summarized below) were finalized after these were
presented to and voted on by a panel of stakeholders.